PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
Found 169 products of "PDE"
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Deltasonamide 2 (TFA)
CAS:Deltasonamide 2 TFA is competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.Formula:C32H40ClF3N6O6S2Purity:98%Color and Shape:SolidMolecular weight:761.28(R)-DNMDP
CAS:(R)-DNMDP is a potent and selective cancer cytotoxic agent that directly binds PDE3A and has an EC50 500-fold lower than that of (S)-DNMDP against HeLa.Formula:C15H20N4O3Color and Shape:SolidMolecular weight:304.34Trequinsin hydrochloride
CAS:Azetirelin (YM 14673) is a new thyrotropin-releasing hormone (TRH) analog.Formula:C24H28ClN3O3Purity:99.95%Color and Shape:SolidMolecular weight:441.95Dovramilast
CAS:Dovramilast (CC-11050) is a PDE4 inhibitor that reduces the production of pro-inflammatory mediators in lupus erythematosus.Formula:C24H28N2O6SPurity:98.75% - 99.62%Color and Shape:SolidMolecular weight:472.55Nanterinone
CAS:Nanterinone: oral phosphodiesterase inhibitor, improves acute heart failure hemodynamics.Formula:C15H15N3OPurity:99.96%Color and Shape:SolidMolecular weight:253.3PF-04447943
CAS:PF-04447943, a selective PDE9A inhibitor (IC50=12nM), may aid sickle cell anemia research with its anti-inflammatory properties.Formula:C20H25N7O2Purity:97.01% - 99.36%Color and Shape:SolidMolecular weight:395.46Isomazole
CAS:Isomazole is a novel orally available phosphodiesterase (PDE) inhibitor with calcium-sensitizing properties that inhibits PDE3 and PDE4.
Formula:C14H13N3O2SPurity:98.66%Color and Shape:SolidMolecular weight:287.34MK-0873
CAS:MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor.Formula:C25H18N4O3Purity:99.14%Color and Shape:SolidMolecular weight:422.44Dasantafil
CAS:Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.Formula:C22H28BrN5O5Purity:99.4% - 99.50%Color and Shape:SolidMolecular weight:522.39PDE IV-IN-1
CAS:PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary diseaseFormula:C20H23ClN4O2Purity:99.79%Color and Shape:SolidMolecular weight:386.88Ref: TM-T10201
1mg225.00€5mg480.00€10mg642.00€25mg964.00€50mg1,288.00€100mg1,738.00€200mg2,332.00€1mL*10mM (DMSO)540.00€Carbazeran
CAS:Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases.Formula:C18H24N4O4Purity:99.3%Color and Shape:SolidMolecular weight:360.41Ref: TM-T21457
2mg42.00€5mg62.00€10mg96.00€25mg170.00€50mg256.00€100mg385.00€1mL*10mM (DMSO)To inquireAutotaxin-IN-3
CAS:Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.Formula:C22H21N9O2Purity:99.54% - 99.79%Color and Shape:SolidMolecular weight:443.46Ref: TM-T10415
2mg43.00€5mg66.00€10mg96.00€25mg173.00€50mg269.00€100mg432.00€200mg592.00€1mL*10mM (DMSO)73.00€Filaminast
CAS:Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.Formula:C15H20N2O4Purity:98.93% - 99.99%Color and Shape:SolidMolecular weight:292.33Ref: TM-T31792
1mg156.00€5mg366.00€10mg487.00€25mg737.00€50mg982.00€100mg1,324.00€200mg1,791.00€1mL*10mM (DMSO)333.00€uk-50001
CAS:UK-50001 is a PDE4 inhibitor for treating inflammation, allergies, respiratory issues, and wounds.Formula:C26H24F3N3O4Purity:99.90%Color and Shape:SolidMolecular weight:499.48Ref: TM-T67815
1mg150.00€5mg360.00€10mg540.00€25mg863.00€50mg1,153.00€100mg1,575.00€500mg3,142.00€1mL*10mM (DMSO)445.00€Mopidamol
CAS:Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimentalFormula:C19H31N7O4Purity:99.31% - 99.78%Color and Shape:SolidMolecular weight:421.49PDE4B-IN-2
CAS:PDE4B-IN-2 (A 33), an oral PDE4B inhibitor, IC50: 15 nM; less potent on PDE4D (IC50: 1.7 µM), has anti-inflammatory properties.Formula:C19H18ClN3O2SPurity:99.32%Color and Shape:SolidMolecular weight:387.88Ref: TM-T36832
1mg37.00€5mg79.00€10mg111.00€25mg216.00€50mg354.00€100mg567.00€500mg1,198.00€1mL*10mM (DMSO)87.00€AWD 12-281
CAS:AWD 12-281 is a PDE4 inhibitor with anti-inflammatory activity and bronchodilator activity for the study of chronic obstructive pulmonary disease (COPD).Formula:C22H14Cl2FN3O3Purity:99.25% - 99.85%Color and Shape:SolidMolecular weight:458.27Tofimilast
CAS:Tofimilast (CP-325366), a PDE4 inhibitor, is used potentially for the treatment of asthma and chronic obstructive pulmonary disease.Formula:C18H21N5SPurity:99.55%Color and Shape:SolidMolecular weight:339.46Verofylline
CAS:Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for theFormula:C12H18N4O2Purity:98.4% - 99.8%Color and Shape:SolidMolecular weight:250.3Gisadenafil besylate
CAS:Gisadenafil besylate (UK 369003-26) is a potent and orally active PDE5 inhibitor, for lower urinary tract symptoms associated with benign prostatic hyperplasia.Formula:C29H39N7O8S2Color and Shape:SolidMolecular weight:677.79
