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Glucokinase

Glucokinase

Glucokinase (GK) is an enzyme that catalyzes the phosphorylation of glucose to glucose-6-phosphate, a critical step in glycolysis. GK is predominantly expressed in the liver and pancreas, where it plays a key role in regulating blood glucose levels. Inhibitors of GK are of interest in the study of metabolic disorders such as diabetes, as they can modulate glucose metabolism and insulin secretion. At CymitQuimica, we provide glucokinase inhibitors to support your research in diabetes, metabolism, and therapeutic development.

Found 55 products for "Glucokinase".

products per page.
  • WAY-640509

    CAS:
    WAY-640509 is a glucocerebrosidase inhibitor.
    Formula:C25H23N5O4S
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:489.546
  • MitoPQ

    CAS:
    MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.
    Formula:C39H46I3N2P
    Purity:99.87% - 99.91%
    Color and Shape:Red Solid
    Molecular weight:954.48
  • Oxfendazole

    CAS:
    Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.
    Formula:C15H13N3O3S
    Purity:98.99% - 99.17%
    Color and Shape:Solid
    Molecular weight:315.35
  • Dorzagliatin

    CAS:
    Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
    Formula:C22H27ClN4O5
    Purity:98.67% - 99.45%
    Color and Shape:Solid
    Molecular weight:462.927
  • MK-0941 free base

    CAS:
    MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.
    Formula:C21H24N4O6S
    Purity:98.75%
    Color and Shape:Solid
    Molecular weight:460.503
  • ML251

    CAS:
    ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.
    Formula:C17H13Cl2N3O4S
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:426.274
  • ML266

    CAS:
    ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.
    Formula:C24H22BrN3O4
    Purity:99.58%
    Color and Shape:White Solid
    Molecular weight:496.353
  • PFKFB3-IN-2

    CAS:
    PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor.
    Formula:C14H11NO7S
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:337.305
  • RO-28-1675

    CAS:
    RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.
    Formula:C18H22N2O3S2
    Purity:98.13%
    Color and Shape:Solid
    Molecular weight:378.509
  • Glucokinase

    CAS:
    Glucokinase is a biochemical reagent used as a biomaterial or organic compound for research in the life sciences.
  • ADP-specific glucokinase

    CAS:
    ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.
    Color and Shape:Solid
  • AP-III-a4 hydrochloride

    CAS:
    AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.
    Formula:C31H44ClFN8O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:631.184
  • (1S,2R)-Globalagliatin

    CAS:
    (1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.
    Formula:C28H37N3O3S3
    Purity:99.05% - 99.17%
    Color and Shape:Solid
    Molecular weight:559.81
  • 5MPN

    CAS:
    5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.
    Formula:C15H19N3O4
    Purity:98.92% - 99.69%
    Color and Shape:Solid
    Molecular weight:305.3291
  • PF-04991532

    CAS:
    PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.
    Formula:C18H19F3N4O3
    Purity:99.99%
    Color and Shape:White Solid
    Molecular weight:396.3637
  • Anti-Glucokinase Antibody (3U461)


    Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.
    Color and Shape:Odour Liquid
  • Anti-Glucokinase Antibody (5Q209)


    Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.
    Color and Shape:Odour Liquid
  • Hex

    CAS:
    Hex is an enolase inhibitor and antimalarial agent with antitumor effects on intracranial tumors.
    Formula:C5H10NO5P
    Color and Shape:Brown Solid
    Molecular weight:195.11
  • Cadisegliatin

    CAS:
    Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.
    Formula:C21H33N3O4S2
    Color and Shape:Solid
    Molecular weight:455.634
  • Glucokinase Protein, Human, Recombinant


    Glucokinase belongs to the bacterial glucokinase family.
    Color and Shape:Lyophilized Powder
    Molecular weight:52.2 kDa (predicted); 52.2 kDa (reducing conditions)