Casein Kinase
Casein kinases are a family of serine/threonine protein kinases that regulate various cellular processes, including DNA repair, circadian rhythms, and signal transduction. These kinases are involved in the phosphorylation of numerous proteins and are implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. At CymitQuimica, we offer a selection of casein kinase inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 151 products for "Casein Kinase".
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Ac-ESMD-CHO
CAS:Ac-ESMD-CHO functions as an inhibitor of both caspase-3 and caspase-7, specifically obstructing the proteolytic cleavage of the caspase-3 precursor peptide (Formula:C19H30N4O10SPurity:98%Color and Shape:SolidMolecular weight:506.53Ellagic acid (hydrate)
CAS:Ellagic acid (hydrate) is a natural antioxidant and acts as a potent and ATP-competitive CK2 inhibitor (IC50:40 nM, Ki: 20 nM).Formula:C14H8O9Purity:98%Color and Shape:SolidMolecular weight:320.2079SB-405483
SB-405483 is a CRBN (Cereblon) positive modulator that facilitates the degradation of CRBN substrates, which include CK1α, Wee1, and IKZF1/3. Furthermore, SB-405483 stabilizes CRBN and reduces its own ubiquitination levels. This compound is applicable in cancer research, such as in studies on multiple myeloma and acute myeloid leukemia.MU1742
MU1742 is a probe for CK1δ and CK1ε protein kinases [1] .Formula:C22H22F2N6Color and Shape:SolidMolecular weight:408.45Casein kinase 1δ-IN-15
CAS:Casein kinase 1δ-IN-15, an inhibitor for casein kinase 1 (CK1δ), exhibits an IC50 of 0.045 μM [1].Formula:C19H17FN6OColor and Shape:SolidMolecular weight:364.38CK2-IN-14
CK2-IN-14 (Compound 10b) is an inhibitor of cyclin-dependent kinase 2α with an IC50 of 36.7 nM. It effectively hinders the growth of cancer cell lines 786-O and U937, with GI50 values of 7.3 μM and 7.5 μM, respectively.Formula:C19H20ClN5SColor and Shape:SolidMolecular weight:385.91QXG-6442
QXG-6442 is a molecular glue degrader targeting CK1α, demonstrating a degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. In the MOLM-14 cell line, QXG-6442 induces antiproliferative effects.Formula:C21H17N5O4Color and Shape:SolidMolecular weight:403.39Casein Kinase Substrates 3
CAS:Casein Kinase Substrates 3 is a substrate of casein kinase.Formula:C85H139N27O35SPurity:98%Color and Shape:SolidMolecular weight:2131.24CK1δ/CK1ε liagnd-1
CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.Formula:C21H20F2N6Color and Shape:SolidMolecular weight:394.42Casein kinase 1δ-IN-9
CAS:Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.Formula:C15H12ClN3Purity:99.93%Color and Shape:White SolidMolecular weight:269.729AH081
AH081 (Compound 38) is a CK1δ/ε PROTAC degrader and serves as the negative control for AH078. It maintains inhibitory activity against CK1δ/ε but lacks degradation activity due to the use of an inactive stereoisomer of the VHL ligand.Color and Shape:Odour SolidCSNK2-IN-2
CSNK2-IN-2 (compound 2) is an orally active inhibitor of CSNK2. It is utilized in antiviral research.Formula:C25H30FN9OColor and Shape:SolidMolecular weight:491.56CK1-IN-3
CAS:WAY-296817 inhibits CK1, potential for circadian rhythm and inflammation research.Formula:C17H16N2O3SPurity:99.18%Color and Shape:SolidMolecular weight:328.386Casein kinase 1δ-IN-14
CAS:Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.Formula:C17H11ClN4O2Purity:99.66%Color and Shape:SolidMolecular weight:338.748SGC-CK2-1
CAS:SGC-CK2-1, a CK2 inhibitor, is a inducer of insulin production and secretion in pancreatic β-cells.Formula:C20H21N7OPurity:99.41%Color and Shape:SolidMolecular weight:375.427MRT00033659
CAS:MRT00033659 inhibits CK1 (IC50=0.9 μM), CHK1 (IC50=0.23 μM), activates p53, and destabilizes E2F-1; it's a pyrazolo-pyridine.Formula:C15H14N4OColor and Shape:SolidMolecular weight:266.2979PF-5006739
CAS:PF-5006739 is a selective CK1δ/ε inhibitor for psychiatric disorder and metabolic research.Formula:C22H22FN7OPurity:99.96%Color and Shape:SolidMolecular weight:419.4548FPFT-2216
CAS:FPFT-2216 is a "molecular glue" compound with potential anti-tumor activity that degrades IKZF6, IKZF1, DE1D and can be used to study immune system diseases.Formula:C12H12N4O3SPurity:99.35% - 99.62%Color and Shape:SolidMolecular weight:292.314DMAT
CAS:DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).Formula:C9H7Br4N3Purity:99.48%Color and Shape:White SolidMolecular weight:476.79TBB
CAS:TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).Formula:C6HBr4N3Purity:98.51% - 99.51%Color and Shape:SolidMolecular weight:434.708
