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Lipase

Lipase

Lipases are enzymes that catalyze the hydrolysis of triglycerides into free fatty acids and glycerol, playing a crucial role in lipid digestion, absorption, and metabolism. Lipase inhibitors are of interest in the treatment of obesity, pancreatitis, and lipid-related metabolic disorders. At CymitQuimica, we provide a variety of lipase inhibitors to support your research in metabolism, obesity, and gastrointestinal health.

Found 78 products for "Lipase".

products per page.
  • Hi 76-0079

    CAS:
    Hi 76-0079: HSL inhibitor, IC50=184 nM; potential for obesity and diabetes research.
    Formula:C11H13ClN2O3
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:256.69
  • JZP-430

    CAS:
    JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM).
    Formula:C16H26N4O3S
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:354.468
  • JW 642

    CAS:
    JW 642 inhibits MAGL in mouse, rat, human brains (IC50: 7.6, 14, 3.7 nM).
    Formula:C21H20F6N2O3
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:462.39
  • DDAO

    CAS:
    DDAO: NIR red fluorescent probe, λem 656 nm, excitation 600-650 nm, detects various enzymes.
    Formula:C15H11Cl2NO2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:308.159
  • LP-922056

    CAS:
    LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
    Formula:C11H9ClN2O2S2
    Purity:99.84%
    Color and Shape:White Solid
    Molecular weight:300.784
  • hPL-IN-1

    CAS:
    hPL-IN-1 is a potent reversible pancreatic lipase (PL) inhibitor (IC50=1.86 μM) that can be used to study obesity-related diseases.
    Formula:C19H11Cl2F2NO3
    Purity:98.41%
    Color and Shape:Soild
    Molecular weight:410.2
  • Lipase Substrate

    CAS:
    Lipase Substrate is a substrate of lipase to detect activity.
    Formula:C45H69NO8
    Color and Shape:Solid
    Molecular weight:752.046
  • Pancreatic lipase-IN-1


    Pancreatic lipase-IN-1 (compound 8) is an inhibitor of pancreatic lipase with a Ki value of 1.288 μM.
    Formula:C35H50O6
    Molecular weight:566.36074
  • hPL-IN-2

    CAS:
    hPL-IN-2 is a potent, reversible and non-competitive inhibitor of Pancreatic lipase (IC50: 1.63 μM) that can be used to investigate obesity-related diseases.
    Formula:C19H11Cl4NO3
    Purity:97.31%
    Color and Shape:Soild
    Molecular weight:443.11
  • 1,2-Dioleoyl-3-behenoylglycerol

    CAS:
    1,2-Dioleoyl-3-behenoylglycerol (BOO) decreases pancreatic lipase activity and hinders the accumulation of visceral fat as well as hepatic triacylglycerol (TAG) [1].
    Formula:C61H114O6
    Molecular weight:943.55
  • Lipstatin

    CAS:
    Lipstatin is a potent inhibitor of the pancreas lipase. It is reported to be useful in the treatment and/or prevention of obesity and related diseases.
    Formula:C29H49NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:491.7
  • Lalistat 2

    CAS:
    Lalistat 2: selective lysosomal acid lipase inhibitor, IC50 152 nM, no effect on pancreatic/milk lipase <10 μM.
    Formula:C13H20N4O2S
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:296.388
  • URB754

    CAS:
    "URB754 inhibits rat MAGL with an IC50 of 200 nM, possibly due to impurity. Weak FAAH and CB1 binding, no COX inhibition. Potential pain management target."
    Formula:C16H14N2O2
    Color and Shape:Solid
    Molecular weight:266.2946
  • Pancreatic lipase-IN-2


    Pancreatic lipase-IN-2 (compound 7r) is a potent inhibitor of pancreatic lipase (PL), with an IC50 value of 2.67 μM, and exhibits anti-obesity effects.
    Formula:C32H33N3O2S
    Color and Shape:Solid
    Molecular weight:523.22935
  • Lipase, triacylglycerol

    CAS:
    Lipase, triacylglycerol (Alkaline lipase) is a specific enzyme catabolism of triacylglycerol to glycerol and fatty acids,transfer to various tissues.
    Formula:C11H9N3NaO2
    Color and Shape:Solid
    Molecular weight:238.201
  • MEDI-5884

    CAS:
    MEDI-5884 is a humanized IgG4Pκ neutralizing monoclonal antibody that targets endothelial lipase (EL). By inhibiting EL, MEDI-5884 leads to an increase in high-density lipoprotein (HDL) levels, particularly phosphatidylinositol and cholesterol ester, thereby enhancing its functionality. This compound is applicable in research related to cardiovascular diseases, such as coronary artery disease (CAD).
  • Cetilistat

    CAS:
    Cetilistat (ATL-962) is a drug for obesity and type 2 diabetes, blocking pancreatic lipase. Developed by Alizyme.
    Formula:C25H39NO3
    Purity:97.12% - 97.47%
    Color and Shape:White Solid
    Molecular weight:401.58
  • Ibrolipim

    CAS:
    Ibrolipim (NO-1886) attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.
    Formula:C19H20BrN2O4P
    Purity:98.04%
    Color and Shape:Solid
    Molecular weight:451.251
  • MAGL-IN-4

    CAS:
    MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
    Formula:C18H21ClN2O4
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:364.823
  • RHC 80267

    CAS:
    RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)
    Formula:C20H34N4O4
    Purity:99.54%
    Color and Shape:White Solid
    Molecular weight:394.51