NAMPT
Nicotinamide Phosphoribosyltransferase (NAMPT) is an enzyme involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+), a critical coenzyme in cellular metabolism and energy production. NAMPT inhibitors are of interest in cancer research due to their ability to disrupt NAD+ metabolism and induce cell death in cancer cells. These inhibitors are also explored in the context of metabolic disorders and aging. At CymitQuimica, we offer NAMPT inhibitors to support your research in cancer biology, metabolism, and aging.
Found 39 products for "NAMPT".
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SBI-797812
CAS:SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).Formula:C19H22N4O4SPurity:99.31%Color and Shape:SolidMolecular weight:402.47Nampt-IN-5
CAS:Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .Formula:C25H25N5O2Purity:99.30%Color and Shape:SolidMolecular weight:427.5Ref: TM-T12171
1mg77.00€5mg147.00€1mL*10mM (DMSO)161.00€10mg250.00€25mg398.00€50mg532.00€100mg735.00€200mg973.00€Nampt activator-1
CAS:NAMPT Activator-1, EC50: 3.3-3.7 µM, specific niacinamide phosphotransferase stimulant, shields cells, potential neuroprotectant.Formula:C16H17N3O3Purity:99.84% - 99.98%Color and Shape:SoildMolecular weight:299.32ALT-100 (Human IgG1)
ALT-100 (Human IgG1) is a neutralizing mAb targeting eNAMPT used to study the treatment mechanisms of myocardial fibrosis and inflammatory diseases by blocking DAMP signaling.Color and Shape:Odour LiquidNampt-IN-10 trihydrochloride
Nampt-IN-10 trihydrochloride, a NAMPT inhibitor, is effective on A2780 & CORL23 cells (IC50: 5/19 nM); potential ADC payload.Formula:C27H31Cl3FN5O2Color and Shape:SolidMolecular weight:582.92Nampt degrader-2
Nampt degrader-2: a fluorescent PROTAC that degrades NAMPT at IC50 41.9 nM, reducing NAD+ and having anti-tumor effects.Formula:C59H73N9O7SColor and Shape:SolidMolecular weight:1052.33NAMPT degrader-3
NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism.Formula:C56H74N8O7SPurity:98%Color and Shape:SolidMolecular weight:1003.3PROTAC NAMPT Degrader-1
PROTACNAMPT Degrader-1 is an effective NAMPT-targeting PROTAC with a DC50 value of 217 nM. It exhibits antiproliferative activity, with an IC50 value of 0.12 μM against A2780 cells.Formula:C57H69N13O8S2Color and Shape:SolidMolecular weight:1127.48335LYP-8
LYP-8 is a potent NAMPT degrader that achieves a maximum degradation rate of 97% in NAMPT within SKOV-3 cells at a concentration of 0.5 μM. LYP-8 also demonstrates anticancer activity both in vitro and in vivo.Formula:C56H74N8O10SColor and Shape:SolidMolecular weight:1050.52486NAMPT activator-7
NAMPTactivator-7 (Compound 232) is an activator of nicotinamide phosphoribosyltransferase (NAMPT) with an EC50 of less than 0.5 μM. It effectively stimulates NAMPT in U2OS cells, demonstrating a cellular EC50 of less than 0.5 μM.Formula:C21H17ClN4O3Color and Shape:SolidMolecular weight:408.09892Nampt-IN-13 FA
Nampt-IN-13 FA is a NAMPT inhibitor (patent WO2021013693A1) suitable for synthesising antibody-drug conjugates (ADCs).Formula:C25H32N6O4Purity:99.06% - 99.30%Color and Shape:Yellow SolidMolecular weight:480.56CB 300919
CAS:CB 300919, a quinazoline antitumor, inhibits CH1 ovarian tumor growth (IC50: 2 nM) over 96h.Formula:C32H34ClN7O2Color and Shape:SolidMolecular weight:584.11NAMPT Protein, Human, Recombinant (His)
Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, butPurity:94% - 94%Color and Shape:Lyophilized PowderMolecular weight:55 KDa (reducing condition)Ref: TM-TMPJ-00968
5µg74.00€10µg108.00€20µg164.00€50µg279.00€100µg479.00€200µg827.00€500µg1,710.00€1mg2,457.00€NAT
CAS:NAT is a nicotinamide phosphoribosyltransferase (NAMPT) activator that increases intracellular NAD levels.Formula:C18H21NO3Purity:99.65%Color and Shape:White SolidMolecular weight:299.36Ref: TM-T60667
1mg38.00€5mg74.00€10mg92.00€1mL*10mM (DMSO)93.00€25mg157.00€50mg222.00€100mg329.00€200mg487.00€(E)-Daporinad
CAS:(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT） .Cost-effective and quality-assured.Formula:C24H29N3O2Purity:98.44% - >99.99%Color and Shape:SolidMolecular weight:391.51Ref: TM-T2644
2mg40.00€5mg62.00€1mL*10mM (DMSO)66.00€10mg90.00€25mg178.00€50mg349.00€100mg528.00€500mg1,108.00€Nampt-IN-1
CAS:Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.Formula:C20H25N3O5SPurity:99.28% - 99.4%Color and Shape:SolidMolecular weight:419.49Ref: TM-T4376
1mg37.00€2mg49.00€5mg79.00€1mL*10mM (DMSO)87.00€10mg130.00€25mg245.00€50mg409.00€100mg605.00€KPT9274
CAS:KPT9274 (PAK4-IN-1) is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.Formula:C35H29F3N4O3Purity:99.75% - 99.93%Color and Shape:SolidMolecular weight:610.62LB-60-OF61 hydrochloride
CAS:LB-60-OF61 hydrochloride is a potent NAMPT enzyme inhibitor with cytotoxic effects, targeting MYC-overexpressing cell lines.Formula:C29H31ClN6O2Color and Shape:SolidMolecular weight:531.06CHS-828
CAS:CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Formula:C19H22ClN5OPurity:98% - 99.9%Color and Shape:SolidMolecular weight:371.86STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Formula:C25H23N3O4SPurity:99.96%Color and Shape:SolidMolecular weight:461.53
