PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Found 164 products of "PPAR"
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T0070907
CAS:<p>T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.</p>Formula:C12H8ClN3O3Purity:98.25% - 99.98%Color and Shape:SolidMolecular weight:277.66Angeloylgomisin H
CAS:<p>Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.</p>Formula:C28H36O8Purity:99.84% - 99.95%Color and Shape:SolidMolecular weight:500.58Oleuropein
CAS:<p>Oleuropein is an antioxidant polyphenol isolated from olive leaf.</p>Formula:C25H32O13Purity:98% - 99.95%Color and Shape:Brown PowderMolecular weight:540.51GSK0660
CAS:<p>GSK0660 is an antagonist and inverse agonist of PPARβ/δ.</p>Formula:C19H18N2O5S2Purity:99.26% - ≥95%Color and Shape:SolidMolecular weight:418.49Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89EPI-001
CAS:<p>EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.</p>Formula:C21H27ClO5Purity:99% - 99.67%Color and Shape:SolidMolecular weight:394.89Clofibrate
CAS:<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Formula:C12H15ClO3Purity:98.77%Color and Shape:Oil LiquidMolecular weight:242.70DG172 dihydrochloride
CAS:<p>DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).</p>Formula:C20H22BrCl2N3Purity:99.87%Color and Shape:SolidMolecular weight:455.2L-165041
CAS:<p>L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)</p>Formula:C22H26O7Purity:97.97%Color and Shape:SolidMolecular weight:402.44GSK3787
CAS:<p>GSK3787 is a specific and irreversible PPARδ inhibitor（pIC50= 6.6）.</p>Formula:C15H12ClF3N2O3SPurity:98% - 99.56%Color and Shape:SolidMolecular weight:392.78Oroxin A
CAS:<p>Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.</p>Formula:C21H20O10Purity:98.05% - 99.74%Color and Shape:SolidMolecular weight:432.38AMG131
CAS:<p>AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for</p>Formula:C21H12Cl4N2O3SPurity:99.37%Color and Shape:SolidMolecular weight:514.21Gypenoside XLIX
CAS:<p>Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry condition</p>Formula:C52H86O21Purity:97.05% - 99.78%Color and Shape:SolidMolecular weight:1047.23Elafibranor
CAS:<p>Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with</p>Formula:C22H24O4SPurity:98.42% - 98.78%Color and Shape:SolidMolecular weight:384.49Cinnamyl alcohol
CAS:<p>Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.</p>Formula:C9H10OPurity:99.00%Color and Shape:Colourless LiquidMolecular weight:134.18Tesaglitazar
CAS:<p>Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα</p>Formula:C20H24O7SPurity:99.95%Color and Shape:SolidMolecular weight:408.47Pparδ agonist 2
CAS:<p>Pparδ agonist 2 is an agonist of PPARδ.</p>Formula:C20H18F3N3O3SPurity:98%Color and Shape:SolidMolecular weight:437.44FTX-6746
CAS:<p>FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.</p>Formula:C16H7ClF2N2OPurity:98.68%Color and Shape:SolidMolecular weight:316.6913-Oxo-9E,11E-octadecadienoic acid
CAS:<p>13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.</p>Formula:C18H30O3Purity:98%Color and Shape:SolidMolecular weight:294.43Peliglitazar racemate
CAS:<p>Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesity</p>Formula:C30H30N2O7Purity:97.75%Color and Shape:SolidMolecular weight:530.57Daltroban
CAS:<p>Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.</p>Formula:C16H16ClNO4SPurity:99.74%Color and Shape:SolidMolecular weight:353.82GW 9578
CAS:<p>GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.</p>Formula:C26H34F2N2O3SPurity:98%Color and Shape:SolidMolecular weight:492.62ARH-049020
CAS:<p>ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.</p>Formula:C24H31NO6Purity:97.19% - 99.82%Color and Shape:SolidMolecular weight:429.51Reglitazar
CAS:<p>Reglitazar, a dual PPARα/γ agonist, enhances insulin signaling, reduces insulin resistance, and lowers hypertriglyceridemia in obese rats.</p>Formula:C22H20N2O5Purity:97.07% - 98.72%Color and Shape:SolidMolecular weight:392.4THR-0921
CAS:<p>THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.</p>Formula:C28H25NO7SPurity:100% - 99.83%Color and Shape:SolidMolecular weight:519.57AVE-8134
CAS:<p>AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.</p>Formula:C22H23NO5Purity:98%Color and Shape:SolidMolecular weight:381.42PPARα-MO-1
CAS:<p>PPARα-MO-1 is a potent modulator of PPARα.</p>Formula:C27H37NO5Purity:98%Color and Shape:SolidMolecular weight:455.59LG100754
CAS:<p>LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.</p>Formula:C26H36O3Color and Shape:SolidMolecular weight:396.56Chiglitazar
CAS:<p>Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.</p>Formula:C36H29FN2O4Color and Shape:SolidMolecular weight:572.63Inolitazone dihydrochloride
CAS:<p>Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.</p>Formula:C27H28Cl2N4O4SColor and Shape:SolidMolecular weight:575.51Saroglitazar
CAS:<p>Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.</p>Formula:C25H29NO4SPurity:98.51%Color and Shape:SolidMolecular weight:439.57GSK376501A
CAS:<p>GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.</p>Formula:C32H37NO6Purity:>99.99%Color and Shape:SolidMolecular weight:531.64Indeglitazar
CAS:<p>Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).</p>Formula:C19H19NO6SPurity:99.45%Color and Shape:SolidMolecular weight:389.42K-111
CAS:<p>K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.</p>Formula:C18H25Cl3O2Purity:99.64% - 99.88%Color and Shape:SolidMolecular weight:379.75Farglitazar
CAS:<p>Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.</p>Formula:C34H30N2O5Purity:99.4% - 99.52%Color and Shape:SolidMolecular weight:546.61Cevoglitazar
CAS:<p>Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.</p>Formula:C27H21F3N2O6SPurity:98.75%Color and Shape:SolidMolecular weight:558.53Dazmegrel
CAS:<p>Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.</p>Formula:C16H17N3O2Purity:98.81%Color and Shape:SolidMolecular weight:283.33BAY-0069
CAS:<p>BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be</p>Formula:C22H16BrN3O4Purity:99.41%Color and Shape:SoildMolecular weight:466.28Linotroban
CAS:<p>Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.</p>Formula:C14H15NO5S2Purity:97.95% - >99.99%Color and Shape:SolidMolecular weight:341.4BAY-4931
CAS:<p>BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.</p>Formula:C22H16ClN3O4Purity:99.47%Color and Shape:SoildMolecular weight:421.83Edaglitazone
CAS:<p>Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.</p>Formula:C24H20N2O4S2Purity:98%Color and Shape:SolidMolecular weight:464.56LCB-2853
CAS:<p>LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.</p>Formula:C21H24ClNO4SPurity:97.15%Color and Shape:SolidMolecular weight:421.94Imiglitazar
CAS:<p>Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.</p>Formula:C28H26N2O5Purity:97.33%Color and Shape:SolidMolecular weight:470.52PPAR agonist 1
CAS:<p>PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.</p>Formula:C20H25NO6SPurity:98%Color and Shape:SolidMolecular weight:407.48U-46619
CAS:<p>U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (</p>Formula:C21H34O4Purity:98%Color and Shape:SolidMolecular weight:350.49KD-3010
CAS:<p>KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.</p>Formula:C30H33F3N2O8S2Purity:99.61%Color and Shape:SolidMolecular weight:670.72CRX000227
CAS:<p>CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].</p>Formula:C25H24N4O2SPurity:98%Color and Shape:SolidMolecular weight:444.55PPARγ agonist 8
CAS:<p>PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferator</p>Formula:C19H12F4O2SPurity:98%Color and Shape:SolidMolecular weight:380.36Darglitazone
CAS:<p>Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.</p>Formula:C23H20N2O4SPurity:99.76%Color and Shape:SolidMolecular weight:420.48PPARδ agonist 9
CAS:<p>PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atherosclerotic</p>Formula:C26H28ClF3N4O3SPurity:98%Color and Shape:SolidMolecular weight:569.04
