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PPAR

PPAR

Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.

Found 164 products of "PPAR"

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  • Daltroban
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    Daltroban

    CAS:
    <p>Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.</p>
    Formula:C16H16ClNO4S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:353.82

    Ref: TM-T15049

  • GW 9578
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    GW 9578

    CAS:
    <p>GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.</p>
    Formula:C26H34F2N2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:492.62

    Ref: TM-T27519

  • ARH-049020
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    ARH-049020

    CAS:
    <p>ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.</p>
    Formula:C24H31NO6
    Purity:97.19% - 99.82%
    Color and Shape:Solid
    Molecular weight:429.51

    Ref: TM-T26656

  • Reglitazar
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    Reglitazar

    CAS:
    <p>Reglitazar, a dual PPARα/γ agonist, enhances insulin signaling, reduces insulin resistance, and lowers hypertriglyceridemia in obese rats.</p>
    Formula:C22H20N2O5
    Purity:97.07% - 98.72%
    Color and Shape:Solid
    Molecular weight:392.4

    Ref: TM-T28511

  • THR-0921
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    THR-0921

    CAS:
    <p>THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.</p>
    Formula:C28H25NO7S
    Purity:100% - 99.83%
    Color and Shape:Solid
    Molecular weight:519.57

    Ref: TM-T69015

  • AVE-8134
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    AVE-8134

    CAS:
    <p>AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.</p>
    Formula:C22H23NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:381.42

    Ref: TM-T14356

  • PPARα-MO-1
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    PPARα-MO-1

    CAS:
    <p>PPARα-MO-1 is a potent modulator of PPARα.</p>
    Formula:C27H37NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:455.59

    Ref: TM-T10505

  • LG100754
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    LG100754

    CAS:
    <p>LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.</p>
    Formula:C26H36O3
    Color and Shape:Solid
    Molecular weight:396.56

    Ref: TM-T15748

  • Chiglitazar
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    Chiglitazar

    CAS:
    <p>Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.</p>
    Formula:C36H29FN2O4
    Color and Shape:Solid
    Molecular weight:572.63

    Ref: TM-T14948

  • Inolitazone dihydrochloride
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    Inolitazone dihydrochloride

    CAS:
    <p>Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.</p>
    Formula:C27H28Cl2N4O4S
    Color and Shape:Solid
    Molecular weight:575.51

    Ref: TM-T15580

  • Saroglitazar
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    Saroglitazar

    CAS:
    <p>Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.</p>
    Formula:C25H29NO4S
    Purity:98.51%
    Color and Shape:Solid
    Molecular weight:439.57

    Ref: TM-T12835

  • GSK376501A
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    GSK376501A

    CAS:
    <p>GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.</p>
    Formula:C32H37NO6
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:531.64

    Ref: TM-T15440

  • Indeglitazar
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    Indeglitazar

    CAS:
    <p>Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).</p>
    Formula:C19H19NO6S
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:389.42

    Ref: TM-T15575

  • K-111
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    K-111

    CAS:
    <p>K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.</p>
    Formula:C18H25Cl3O2
    Purity:99.64% - 99.88%
    Color and Shape:Solid
    Molecular weight:379.75

    Ref: TM-T27706

  • Farglitazar
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    Farglitazar

    CAS:
    <p>Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.</p>
    Formula:C34H30N2O5
    Purity:99.4% - 99.52%
    Color and Shape:Solid
    Molecular weight:546.61

    Ref: TM-T27303

  • Cevoglitazar
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    Cevoglitazar

    CAS:
    <p>Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.</p>
    Formula:C27H21F3N2O6S
    Purity:98.75%
    Color and Shape:Solid
    Molecular weight:558.53

    Ref: TM-T26986

  • Dazmegrel
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    Dazmegrel

    CAS:
    <p>Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.</p>
    Formula:C16H17N3O2
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:283.33

    Ref: TM-T31213

  • BAY-0069
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    BAY-0069

    CAS:
    <p>BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be</p>
    Formula:C22H16BrN3O4
    Purity:99.41%
    Color and Shape:Soild
    Molecular weight:466.28

    Ref: TM-T67936

  • Linotroban
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    Linotroban

    CAS:
    <p>Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.</p>
    Formula:C14H15NO5S2
    Purity:97.95% - >99.99%
    Color and Shape:Solid
    Molecular weight:341.4

    Ref: TM-T25741

  • BAY-4931
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    BAY-4931

    CAS:
    <p>BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.</p>
    Formula:C22H16ClN3O4
    Purity:99.47%
    Color and Shape:Soild
    Molecular weight:421.83

    Ref: TM-T67933