AhR
The Aryl Hydrocarbon Receptor (AhR) is a ligand-activated transcription factor that plays a critical role in the regulation of biological responses to environmental contaminants, such as dioxins. AhR is also involved in the metabolism of xenobiotics and the regulation of immune responses, cell proliferation, and differentiation. Dysregulation of AhR signaling is linked to various diseases, including cancer and autoimmune disorders. At CymitQuimica, we offer a range of AhR inhibitors to support your research in toxicology, cancer biology, and immunology.
Found 41 products of "AhR"
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GNF351
CAS:<p>GNF351: Full AHR antagonist, inhibits DRE-dependent/independent activity, low toxicity, binds AHR (IC50: 62 nM).</p>Formula:C24H25N7Purity:98.43%Color and Shape:SolidMolecular weight:411.5Diosmin
CAS:<p>Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.</p>Formula:C28H32O15Purity:97.90%Color and Shape:Greyish-Yellow Or Light Yellow Hygroscopic PowderMolecular weight:608.54Mexiletine hydrochloride
CAS:<p>Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.</p>Formula:C11H18ClNOPurity:99.88%Color and Shape:White To Off-White SolidMolecular weight:215.72BAY 2416964
CAS:<p>BAY 2416964 is a small molecule inhibitor that selectively targets aromatic receptor (AhR) and is commonly used in tumor research. Cost-effective and quality-assured.</p>Formula:C18H18ClN5O3Purity:99.15% - 99.85%Color and Shape:SolidMolecular weight:387.82Leflunomide
CAS:<p>Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.</p>Formula:C12H9F3N2O2Purity:99.52% - 99.96%Color and Shape:Off White Crystalline SolidMolecular weight:270.21StemRegenin 1 Hydrochloride
CAS:<p>StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.</p>Formula:C24H24ClN5OSPurity:99.94%Color and Shape:SolidMolecular weight:466KYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Formula:C22H19FN6Purity:98.35%Color and Shape:SolidMolecular weight:386.43MeBIO
CAS:<p>MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.</p>Formula:C17H12BrN3O2Purity:99.64%Color and Shape:SolidMolecular weight:370.2WAY-605471
CAS:<p>WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.</p>Formula:C14H15NO3S2Purity:99.62%Color and Shape:SolidMolecular weight:309.4AHR Inhibitor I-103
CAS:<p>AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.</p>Formula:C21H17FN6Purity:98.70%Color and Shape:SoildMolecular weight:372.43',4'-Dimethoxyflavone
CAS:<p>3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.</p>Formula:C17H14O4Purity:98.05%Color and Shape:SolidMolecular weight:282.29L-Kynurenine
CAS:<p>L-Kynurenine ((S)-Kynurenine)) is an endogenous agonist of aryl hydrocarbon receptor (AHR) ,inhibits allogeneic T cell proliferation. High-Quality, Low-Cost!</p>Formula:C10H12N2O3Purity:98.44% - 99.91%Color and Shape:Light Yellow CrystallineMolecular weight:208.21YL-109
CAS:<p>YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.</p>Formula:C14H11NO2SPurity:99.77% - ≥95%Color and Shape:SolidMolecular weight:257.31ITE
CAS:<p>ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.</p>Formula:C14H10N2O3SPurity:97.91% - 99.14%Color and Shape:SolidMolecular weight:286.31PDM11
CAS:<p>PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)</p>Formula:C16H15ClO2Purity:99.88%Color and Shape:SolidMolecular weight:274.74Benzyl butyl phthalate
CAS:<p>Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.</p>Formula:C19H20O4Purity:99.02%Color and Shape:Colourless Liquid Oily LiquidMolecular weight:312.36Indole-3-pyruvic acid
CAS:<p>Indole-3-pyruvic acid is a precursor for the plant growth hormone indole-3-acetic acid.</p>Formula:C11H9NO3Purity:98.89% - 99.21%Color and Shape:Off White CrystalsMolecular weight:203.19Tapinarof
CAS:<p>Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.</p>Formula:C17H18O2Purity:99.64% - >99.99%Color and Shape:SolidMolecular weight:254.32PD98059
CAS:<p>PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.</p>Formula:C16H13NO3Purity:98.63% - >99.99%Color and Shape:Yellow SolidMolecular weight:267.28Carbidopa
CAS:<p>Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).</p>Formula:C10H14N2O4Purity:98.01% - ≥98%Color and Shape:SolidMolecular weight:226.23
