AhR
The Aryl Hydrocarbon Receptor (AhR) is a ligand-activated transcription factor that plays a critical role in the regulation of biological responses to environmental contaminants, such as dioxins. AhR is also involved in the metabolism of xenobiotics and the regulation of immune responses, cell proliferation, and differentiation. Dysregulation of AhR signaling is linked to various diseases, including cancer and autoimmune disorders. At CymitQuimica, we offer a range of AhR inhibitors to support your research in toxicology, cancer biology, and immunology.
Found 42 products of "AhR"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Leflunomide
CAS:Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.Formula:C12H9F3N2O2Purity:99.52% - 99.96%Color and Shape:Off White Crystalline SolidMolecular weight:270.21Mexiletine hydrochloride
CAS:Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Formula:C11H18ClNOPurity:99.88%Color and Shape:White To Off-White SolidMolecular weight:215.72BAY 2416964
CAS:BAY 2416964 is a small molecule inhibitor that selectively targets aromatic receptor (AhR) and is commonly used in tumor research. Cost-effective and quality-assured.Formula:C18H18ClN5O3Purity:99.15% - 99.85%Color and Shape:SolidMolecular weight:387.82Ref: TM-T10270
1mg48.00€5mg85.00€1mL*10mM (DMSO)87.00€10mg120.00€25mg235.00€50mg354.00€100mg567.00€200mg793.00€Nimodipine
CAS:Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.Formula:C21H26N2O7Purity:99.64% - 99.79%Color and Shape:SolidMolecular weight:418.44GNF351
CAS:GNF351: Full AHR antagonist, inhibits DRE-dependent/independent activity, low toxicity, binds AHR (IC50: 62 nM).Formula:C24H25N7Purity:98.43%Color and Shape:SolidMolecular weight:411.5Ref: TM-T15410
1mg42.00€5mg89.00€1mL*10mM (DMSO)100.00€10mg137.00€25mg268.00€50mg492.00€100mg662.00€200mg895.00€Diosmin
CAS:Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.Formula:C28H32O15Purity:97.90%Color and Shape:Greyish-Yellow Or Light Yellow Hygroscopic PowderMolecular weight:608.54WAY-605471
CAS:WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Formula:C14H15NO3S2Purity:99.62%Color and Shape:SolidMolecular weight:309.4KYN-101
CAS:KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.
Formula:C22H19FN6Purity:98.35%Color and Shape:SolidMolecular weight:386.43AHR Inhibitor I-103
CAS:AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.Formula:C21H17FN6Purity:98.70%Color and Shape:SoildMolecular weight:372.43',4'-Dimethoxyflavone
CAS:3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.Formula:C17H14O4Purity:98.05%Color and Shape:SolidMolecular weight:282.29StemRegenin 1 Hydrochloride
CAS:StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.Formula:C24H24ClN5OSPurity:99.94%Color and Shape:SolidMolecular weight:466MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Formula:C17H12BrN3O2Purity:99.64%Color and Shape:SolidMolecular weight:370.2Ref: TM-T21966
1mg39.00€5mg74.00€1mL*10mM (DMSO)86.00€10mg117.00€25mg220.00€50mg354.00€100mg520.00€500mg1,130.00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purity:98.63% - >99.99%Color and Shape:Yellow SolidMolecular weight:267.28Ref: TM-T2623
5mg38.00€10mg50.00€1mL*10mM (DMSO)55.00€25mg78.00€50mg101.00€100mg168.00€200mg250.00€500mg421.00€Indole-3-pyruvic acid
CAS:Indole-3-pyruvic acid is a precursor for the plant growth hormone indole-3-acetic acid.Formula:C11H9NO3Purity:98.89% - 99.21%Color and Shape:Off White CrystalsMolecular weight:203.19VAF347
CAS:VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.Formula:C17H11ClF3N3Purity:98.75% - 99.55%Color and Shape:SolidMolecular weight:349.74Ref: TM-T13276
1mg38.00€2mg49.00€5mg80.00€1mL*10mM (DMSO)107.00€10mg113.00€25mg200.00€50mg334.00€100mg500.00€500mg1,099.00€5-fluoro 203
CAS:5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts.Formula:C14H11FN2SPurity:97.61%Color and Shape:SolidMolecular weight:258.31Ref: TM-T21704
1mL*10mM (DMSO)43.00€5mg44.00€10mg64.00€25mg116.00€50mg172.00€100mg249.00€200mg354.00€Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFormula:C9H9NOPurity:98.59% - >99.99%Color and Shape:SolidMolecular weight:147.17Benzyl butyl phthalate
CAS:Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.Formula:C19H20O4Purity:99.02%Color and Shape:Colourless Liquid Oily LiquidMolecular weight:312.36FICZ
CAS:FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).Formula:C19H12N2OPurity:98.97%Color and Shape:SolidMolecular weight:284.31Ref: TM-TQ0257
1mg50.00€5mg96.00€10mg131.00€1mL*10mM (DMSO)133.00€25mg248.00€50mg419.00€100mg592.00€200mg845.00€CH-223191
CAS:CH-223191, a specific aryl hydrocarbon receptor (AhR) antagonist, inhibited TCDD-induced luciferase activity with an IC50 of 0.03 μM. High-Quality, Low-Cost!Formula:C19H19N5OPurity:99.01% - 99.71%Color and Shape:SolidMolecular weight:333.39L-Kynurenine
CAS:L-Kynurenine ((S)-Kynurenine)) is an endogenous agonist of aryl hydrocarbon receptor (AHR) ,inhibits allogeneic T cell proliferation. High-Quality, Low-Cost!Formula:C10H12N2O3Purity:98.44% - 99.91%Color and Shape:Light Yellow CrystallineMolecular weight:208.21BAY-218
CAS:Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.Formula:C20H17ClFN3O3Purity:99.46% - 99.85%Color and Shape:SolidMolecular weight:401.82Ref: TM-T5622
1mg38.00€2mg52.00€5mg69.00€1mL*10mM (DMSO)74.00€10mg109.00€25mg236.00€50mg378.00€100mg592.00€Carbidopa
CAS:Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).Formula:C10H14N2O4Purity:98.01% - ≥98%Color and Shape:SolidMolecular weight:226.23Tapinarof
CAS:Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.Formula:C17H18O2Purity:99.64% - >99.99%Color and Shape:SolidMolecular weight:254.32PDM11
CAS:PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)Formula:C16H15ClO2Purity:99.88%Color and Shape:SolidMolecular weight:274.74ITE
CAS:ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.Formula:C14H10N2O3SPurity:97.91% - 99.14%Color and Shape:SolidMolecular weight:286.31CAY 10465
CAS:CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).Formula:C15H9Cl2F3Purity:98.80%Color and Shape:SolidMolecular weight:317.13Ref: TM-T4607
1mg34.00€2mg49.00€5mg73.00€1mL*10mM (DMSO)81.00€10mg104.00€25mg215.00€50mg408.00€100mg618.00€Carbidopa monohydrate
CAS:Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.Formula:C10H16N2O5Purity:98.11% - 98.30%Color and Shape:SolidMolecular weight:244.24StemRegenin 1
CAS:StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.Formula:C24H23N5OSPurity:98% - 99.89%Color and Shape:SolidMolecular weight:429.54PDM2
CAS:PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.Formula:C14H9Cl3Purity:99.44%Color and Shape:SolidMolecular weight:283.58Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurity:99.74%Color and Shape:Leaves From Petroleum Ether; White-Brown Scales SolidMolecular weight:131.17Brevifolincarboxylic acid
CAS:Natural α-glucosidase inhibitor from Polygonum capitatum; blocks AhR with 323.46 μM IC50.Formula:C13H8O8Purity:99.42% - 99.59%Color and Shape:SolidMolecular weight:292.201,4-Chrysenequinone
CAS:1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).Formula:C18H10O2Purity:99.07% - 99.84%Color and Shape:SolidMolecular weight:258.27Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurity:97.71% - >99.99%Color and Shape:SolidMolecular weight:367.3YL-109
CAS:YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.Formula:C14H11NO2SPurity:99.77% - ≥95%Color and Shape:SolidMolecular weight:257.31Ref: TM-T1960
2mg34.00€5mg49.00€1mL*10mM (DMSO)50.00€10mg75.00€25mg114.00€50mg178.00€100mg260.00€200mg385.00€500mg628.00€DiMNF
CAS:Imigliptin (KBP 3853) is a dipeptidyl peptidase-4 inhibitor used in the study of type 2 diabetes.Formula:C21H16O4Purity:97.60%Color and Shape:SolidMolecular weight:332.35L-Kynurenine-d4
CAS:L-Kynurenine-d4 is a deuterated isotope compound of L-Kynurenine. L-Kynurenine is a metabolite of tryptophan and an endogenous agonist of the AHR.Formula:C10H8D4N2O3Color and Shape:SolidMolecular weight:212.24D-Kynurenine
CAS:D-Kynurenine, ZINC901103, metabolizes from D-tryptophan, activates AhR, changes epithelium to mesenchyme, and tests for D-amino acid oxidase.Formula:C10H12N2O3Purity:99.68%Color and Shape:SolidMolecular weight:208.21Phortress
CAS:Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumorFormula:C20H25Cl2FN4OSPurity:99.89%Color and Shape:SolidMolecular weight:459.41Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formula:C15H16Cl3N3O2Purity:99.75% - 99.79%Color and Shape:Colorless SolidMolecular weight:376.67CAY10464
CAS:CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.Formula:C15H12Cl2OPurity:99.96%Color and Shape:SolidMolecular weight:279.16AhR agonist 2
AhR agonist 2 is aryl hydrocarbon receptor (AhR) agonist,oral, inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair,psoriasis.Formula:C12H7Br2N3Color and Shape:SolidMolecular weight:353.01
