Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 124 products of "Lipoxygenase"
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β-Boswellic acid
CAS:<p>β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic</p>Formula:C30H48O3Purity:99.2% - 99.91%Color and Shape:Off-White SolidMolecular weight:456.7ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:<p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>Formula:C12H13NO3Purity:98.9%Color and Shape:Off-White To Light Tan Crystalline PowderMolecular weight:219.24BI-0115
CAS:<p>BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.</p>Formula:C15H14ClN3OPurity:99.34%Color and Shape:SolidMolecular weight:287.74Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Formula:C17H14O6Purity:98.67% - 99.88%Color and Shape:SolidMolecular weight:314.29Caffeic Acid
CAS:<p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>Formula:C9H8O4Purity:98.89% - 99.3%Color and Shape:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Molecular weight:180.162,5-Di-tert-butylhydroquinone
CAS:<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Formula:C14H22O2Purity:97.11%Color and Shape:PelletslargecrystalsMolecular weight:222.32Tepoxalin
CAS:<p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>Formula:C20H20ClN3O3Purity:99.94%Color and Shape:SolidMolecular weight:385.845-O-Demethylnobiletin
CAS:<p>5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.</p>Formula:C20H20O8Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:388.37FPL 62064
CAS:<p>FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin</p>Formula:C16H15N3OPurity:98.79%Color and Shape:SolidMolecular weight:265.31ML351
CAS:<p>ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).</p>Formula:C15H11N3OPurity:97.67%Color and Shape:SolidMolecular weight:249.27Linoleyl alcohol
CAS:<p>Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].</p>Formula:C18H34OPurity:98.12%Color and Shape:SolidMolecular weight:266.463-Hydroxycoumarin
CAS:<p>3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors</p>Formula:C9H6O3Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:162.14ML355
CAS:<p>ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.</p>Formula:C21H19N3O4S2Purity:98.02% - 98.2%Color and Shape:SolidMolecular weight:441.5211-Keto-β-boswellic acid
CAS:<p>11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.</p>Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Terameprocol
CAS:<p>Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.</p>Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25CAY10698
CAS:<p>CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).</p>Formula:C17H17N3O4S2Purity:98.97%Color and Shape:SolidMolecular weight:391.46U-73122
CAS:<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.645-LOX inhibitor
CAS:<p>5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is an itraconazole impurity, a LOX-5 inhibitor.</p>Formula:C22H27N5O2Purity:98.01%Color and Shape:SolidMolecular weight:393.48a-Boswellic Acid
CAS:Controlled Product<p>Applications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.<br>References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);<br></p>Formula:C30H48O3Color and Shape:NeatMolecular weight:456.70Golocdacimab
CAS:<p>Golocdacimab (anti-LOX-1 mAb) targets LOX-1, with potential applications for type 2 diabetes complications and preventing HAE attacks.</p>Purity:95%Color and Shape:Liquid4-(2-Methylpropyl)benzenemethanol
CAS:Controlled ProductFormula:C11H16OColor and Shape:NeatMolecular weight:164.24tHGA
CAS:<p>tHGA is a potent inhibitor of lipoxygenase.</p>Formula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38BI-L 357
CAS:<p>BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.</p>Formula:C18H18O4SColor and Shape:SolidMolecular weight:330.4L 652343
CAS:<p>L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.</p>Formula:C22H14F3NO2S2Color and Shape:SolidMolecular weight:445.482-TEDC
CAS:<p>2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.</p>Formula:C16H13NO4SPurity:99.75%Color and Shape:SolidMolecular weight:315.34Atreleuton
CAS:<p>Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.</p>Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37RWJ 63556
CAS:<p>RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.</p>Formula:C11H10FNO3S2Purity:99.92%Color and Shape:SolidMolecular weight:287.33AHR-5333
CAS:<p>AHR-5333 an antiallergy agent.</p>Formula:C30H33F2NO4Purity:98%Color and Shape:SolidMolecular weight:509.58PF-4191834
CAS:<p>PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.</p>Formula:C22H23N3O2SPurity:99.83% - 99.98%Color and Shape:SolidMolecular weight:393.5Enazadrem
CAS:<p>Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.</p>Formula:C18H25N3OPurity:98%Color and Shape:SolidMolecular weight:299.41Fluindione
CAS:<p>Fluindione is a hematologic drug.</p>Formula:C15H9FO2Color and Shape:SolidMolecular weight:240.23LY 269415
CAS:<p>LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.</p>Formula:C19H28N2O2SColor and Shape:SolidMolecular weight:348.5YS-121
CAS:<p>YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>Formula:C20H26ClN3O2SColor and Shape:SolidMolecular weight:407.96Lipoxygenin
CAS:<p>Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.</p>Formula:C24H22N2O4Color and Shape:SolidMolecular weight:402.44LP117
CAS:<p>LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).</p>Formula:C21H23ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:430.95ICI 211965
CAS:<p>ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).</p>Formula:C24H23NO2SPurity:98%Color and Shape:SolidMolecular weight:389.51Fenleuton
CAS:<p>Fenleuton is a 5-lipoxygenase inhibitor.</p>Formula:C17H15FN2O3Purity:98%Color and Shape:SolidMolecular weight:314.31LY 221068
CAS:<p>LY 221068 is a potent antioxidant with anti-inflammatory activity.</p>Formula:C20H30N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.53L 656224
CAS:<p>L 656224 is a 5-LO inhibitor.</p>Formula:C20H21ClO3Purity:98%Color and Shape:SolidMolecular weight:344.83Texasin
CAS:<p>Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.</p>Formula:C16H12O5Purity:98%Color and Shape:SolidMolecular weight:284.26Cgp 8065
CAS:<p>Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.</p>Formula:C16H15N3O4S2Color and Shape:SolidMolecular weight:377.44EP6
CAS:<p>EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.</p>Formula:C24H30N4OPurity:98%Color and Shape:SolidMolecular weight:390.52HZ52
CAS:<p>HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.</p>Formula:C24H26ClN3O2SColor and Shape:SolidMolecular weight:456RG 6866
CAS:<p>RG 6866 is a inhibitor of 5-lipoxygenase.</p>Formula:C16H17NO3Purity:98%Color and Shape:SolidMolecular weight:271.31L-651392
CAS:<p>L-651392 is an inhibitor of leukotriene.</p>Formula:C14H10BrNO3SColor and Shape:SolidMolecular weight:352.2MLS000536924
CAS:<p>MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.</p>Formula:C16H15N3SColor and Shape:SolidMolecular weight:281.38A-69412
CAS:<p>A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.</p>Formula:C7H10N2O3Purity:99.54%Color and Shape:SolidMolecular weight:170.17Utreloxastat
CAS:<p>Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis<br>.</p>Formula:C18H28O2Purity:99.95%Color and Shape:SolidMolecular weight:276.41Butibufen
CAS:<p>Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.</p>Formula:C14H20O2Purity:98.11% - 98.91%Color and Shape:SolidMolecular weight:220.31
