Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 133 products of "Lipoxygenase"
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Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36β-Boswellic acid
CAS:β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemicFormula:C30H48O3Purity:99.2% - 99.96%Color and Shape:Off-White SolidMolecular weight:456.70Ref: TM-TN1097
1mg58.00€5mg137.00€10mg212.00€25mg363.00€50mg527.00€100mg747.00€1mL*10mM (DMSO)161.00€ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.Formula:C12H13NO3Purity:98.9%Color and Shape:Off-White To Light Tan Crystalline PowderMolecular weight:219.24BI-0115
CAS:BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.Formula:C15H14ClN3OPurity:99.34%Color and Shape:SolidMolecular weight:287.74Pectolinarigenin
CAS:Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.Formula:C17H14O6Purity:98.67% - 99.88%Color and Shape:SolidMolecular weight:314.29Ref: TM-T6S0413
1mg46.00€5mg89.00€10mg154.00€25mg265.00€50mg409.00€100mg620.00€1mL*10mM (DMSO)110.00€Caffeic Acid
CAS:Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!Formula:C9H8O4Purity:98.89% - 99.3%Color and Shape:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Molecular weight:180.164',5-Dihydroxyflavone
CAS:4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).Formula:C15H10O4Purity:99.81%Color and Shape:SolidMolecular weight:254.242,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formula:C14H22O2Purity:97.11%Color and Shape:PelletslargecrystalsMolecular weight:222.32Tepoxalin
CAS:Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.Formula:C20H20ClN3O3Purity:99.94%Color and Shape:SolidMolecular weight:385.84Ref: TM-T7724
1mg52.00€5mg113.00€10mg166.00€25mg371.00€50mg557.00€100mg792.00€200mg1,071.00€1mL*10mM (DMSO)126.00€5-O-Demethylnobiletin
CAS:5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.
Formula:C20H20O8Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:388.37FPL 62064
CAS:FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFormula:C16H15N3OPurity:98.79%Color and Shape:SolidMolecular weight:265.31Ref: TM-T8356
2mg35.00€5mg52.00€10mg86.00€25mg136.00€50mg198.00€100mg298.00€200mg414.00€1mL*10mM (DMSO)73.00€ML351
CAS:ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Formula:C15H11N3OPurity:97.67%Color and Shape:SolidMolecular weight:249.27Ref: TM-T21902
1mg50.00€5mg105.00€10mg167.00€25mg334.00€50mg505.00€100mg713.00€1mL*10mM (DMSO)117.00€Linoleyl alcohol
CAS:Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].Formula:C18H34OPurity:98.12%Color and Shape:SolidMolecular weight:266.463-Hydroxycoumarin
CAS:3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFormula:C9H6O3Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:162.1411-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Ref: TM-TN1182
1mg57.00€5mg130.00€10mg200.00€25mg338.00€50mg497.00€100mg710.00€1mL*10mM (DMSO)133.00€Terameprocol
CAS:Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25Ref: TM-T3384
1mg34.00€5mg71.00€10mg109.00€25mg175.00€50mg314.00€100mg414.00€500mg954.00€1mL*10mM (DMSO)50.00€CAY10698
CAS:CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).Formula:C17H17N3O4S2Purity:98.97%Color and Shape:SolidMolecular weight:391.46Ref: TM-T8950
2mg38.00€5mg52.00€10mg88.00€25mg161.00€50mg243.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)62.00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.64a-Boswellic Acid
CAS:Controlled ProductApplications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);Formula:C30H48O3Color and Shape:NeatMolecular weight:456.74-(2-Methylpropyl)benzenemethanol
CAS:Controlled ProductFormula:C11H16OColor and Shape:NeatMolecular weight:164.24MLS000536924
CAS:MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Formula:C16H15N3SColor and Shape:SolidMolecular weight:281.38tHGA
CAS:tHGA is a potent inhibitor of lipoxygenase.Formula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38L 652343
CAS:L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.Formula:C22H14F3NO2S2Color and Shape:SolidMolecular weight:445.48AHR-5333
CAS:AHR-5333 an antiallergy agent.Formula:C30H33F2NO4Purity:98%Color and Shape:SolidMolecular weight:509.58PF-4191834
CAS:PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Formula:C22H23N3O2SPurity:99.83% - 99.98%Color and Shape:SolidMolecular weight:393.5Ref: TM-T16503
5mg50.00€10mg79.00€25mg146.00€50mg245.00€100mg355.00€500mg772.00€1mL*10mM (DMSO)55.00€Texasin
CAS:Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.Formula:C16H12O5Purity:98%Color and Shape:SolidMolecular weight:284.26L-651392
CAS:L-651392 is an inhibitor of leukotriene.Formula:C14H10BrNO3SColor and Shape:SolidMolecular weight:352.2SB 210661
CAS:SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Formula:C16H14F2N2O4Purity:98%Color and Shape:SolidMolecular weight:336.29Enazadrem
CAS:Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
Formula:C18H25N3OPurity:98%Color and Shape:SolidMolecular weight:299.41Nafazatrom
CAS:Nafazatrom: pyrazolinone lipoxygenase inhibitor, anticancer & antithrombotic, boosts PGI2, reduces arrhythmias.Formula:C16H16N2O2Color and Shape:SolidMolecular weight:268.31LY 221068
CAS:LY 221068 is a potent antioxidant with anti-inflammatory activity.Formula:C20H30N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.5315(S)-HETrE
CAS:15(S)-HETrE, a 15-lipoxygenated DGLA derivative, inhibits human 5-LO with IC50 of 4.6μM; 5% as effective in RBL cells.Formula:C20H34O3Color and Shape:SolidMolecular weight:322.48AHR-5333 mandelate
CAS:AHR-5333 mandelate is an anti-allergy agent preventing anaphylaxis and skin hypersensitivity; inhibits 5-HETE, LTB4, LTC4 synthesis.Formula:C38H41F2NO7Color and Shape:SolidMolecular weight:661.7413(S)-HpOTrE(γ)
CAS:13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.Formula:C18H30O4Color and Shape:SolidMolecular weight:310.43Leukotriene A3 methyl ester
CAS:LTA3, made from 5,8,11-eicosatrienoic acid via 5-LO, is unstable; its stable methyl ester form turns into free acid when needed.Formula:C21H34O3Color and Shape:SolidMolecular weight:334.49Setileuton tosylate
CAS:Setileuton (MK0633): a potent 5-lipoxygenase inhibitor, researched for asthma and atherosclerosis treatment.Formula:C29H25F4N3O7SColor and Shape:SolidMolecular weight:635.58Atreleuton
CAS:Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37YS-121
CAS:YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).Formula:C20H26ClN3O2SColor and Shape:SolidMolecular weight:407.96LP117
CAS:LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).Formula:C21H23ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:430.95Fenleuton
CAS:Fenleuton is a 5-lipoxygenase inhibitor.Formula:C17H15FN2O3Purity:98%Color and Shape:SolidMolecular weight:314.31L 656224
CAS:L 656224 is a 5-LO inhibitor.Formula:C20H21ClO3Purity:98%Color and Shape:SolidMolecular weight:344.83RG 6866
CAS:RG 6866 is a inhibitor of 5-lipoxygenase.Formula:C16H17NO3Purity:98%Color and Shape:SolidMolecular weight:271.31ICI 211965
CAS:ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).Formula:C24H23NO2SPurity:98%Color and Shape:SolidMolecular weight:389.51EP6
CAS:EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.Formula:C24H30N4OPurity:98%Color and Shape:SolidMolecular weight:390.52HZ52
CAS:HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.Formula:C24H26ClN3O2SColor and Shape:SolidMolecular weight:456Cgp 8065
CAS:Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.Formula:C16H15N3O4S2Color and Shape:SolidMolecular weight:377.44Fluindione
CAS:Fluindione is a hematologic drug.Formula:C15H9FO2Color and Shape:SolidMolecular weight:240.23Lipoxygenin
CAS:Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.Formula:C24H22N2O4Color and Shape:SolidMolecular weight:402.44BI-L 357
CAS:BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formula:C18H18O4SColor and Shape:SolidMolecular weight:330.4
