Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 124 products of "Lipoxygenase"
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5-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Formula:C22H18N6O4Color and Shape:SolidMolecular weight:430.422-Methyl-1-naphthol
CAS:<p>2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.</p>Formula:C11H10OPurity:98.33%Color and Shape:SolidMolecular weight:158.2LOX-IN-5
CAS:<p>LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.</p>Formula:C21H25FN4O2SColor and Shape:SolidMolecular weight:416.51ZD-2138
CAS:<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Formula:C23H24FNO4Purity:99.68% - >99.99%Color and Shape:SolidMolecular weight:397.44(-)-Dihydroguaiaretic acid
<p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>Formula:C20H26O4Color and Shape:SolidMolecular weight:330.424mPGES-1/5-LOX-IN-1
<p>mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.</p>Formula:C20H22N4O6SMolecular weight:446.12601Ruthenoleuton
<p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>Formula:C13H16N2O2RuColor and Shape:SolidMolecular weight:333.35E 6080 HCl
CAS:<p>E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.</p>Formula:C17H20ClN3O3S2Purity:99.80%Color and Shape:SoildMolecular weight:413.94h15-LOX-2 inhibitor 2
<p>Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.</p>Formula:C22H30Cl2N6O3Color and Shape:SolidMolecular weight:497.42DKI5
CAS:<p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>Formula:C8H10N4SPurity:98%Color and Shape:SoildMolecular weight:194.26CBS-1114 HCl
CAS:<p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>Formula:C13H14ClN3Purity:99.36%Color and Shape:SoildMolecular weight:247.72Zileuton sodium
CAS:<p>Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.</p>Formula:C11H11N2NaO2SColor and Shape:SolidMolecular weight:258.27Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:<p>Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can Trust</p>Formula:C19H15NO4Color and Shape:SolidMolecular weight:321.33Phenidone
CAS:<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Formula:C9H10N2OPurity:97.24%Color and Shape:White Solid Solid CrystallineMolecular weight:162.19Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purity:97.82% - 99.91%Color and Shape:SolidMolecular weight:302.36Malotilate
CAS:<p>Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.</p>Formula:C12H16O4S2Purity:99.79% - 99.79%Color and Shape:SolidMolecular weight:288.38β-Aminopropionitrile hydrochloride
CAS:<p>β-Aminopropionitrile hydrochloride is a selective, oral, irreversible inhibitor of lysyl oxidase (LOX) that reduces metastatic seeding potential.</p>Formula:C3H7ClN2Purity:99.32%Color and Shape:SolidMolecular weight:106.55SKF-86002
CAS:<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Formula:C16H12FN3SPurity:98% - 99.85%Color and Shape:SolidMolecular weight:297.35Phenethyl ferulate
CAS:<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Formula:C18H18O4Purity:99.88% - 99.91%Color and Shape:SolidMolecular weight:298.33β-Boswellic acid
CAS:<p>β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic</p>Formula:C30H48O3Purity:99.2% - 99.91%Color and Shape:Off-White SolidMolecular weight:456.7
