Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
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Esculetin
CAS:305-01-1
Esculetin: a coumarin from plants with anti-edema, anti-inflammatory, anti-tumor properties; inhibits LOs.
Formula:
C9H6O4
Purity:
98.43% - 99.76%
Color and Shape:
Yellow Crystalline Powder
Molecular weight:
178.14
Ref: TM-T2798
| 100mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
4',5-Dihydroxyflavone
CAS:6665-67-4
4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).
Formula:
C15H10O4
Purity:
95.38%
Color and Shape:
Solid
Molecular weight:
254.24
Ref: TM-T8260
| 5mg | 40.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 254.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
2,5-Di-tert-butylhydroquinone
CAS:88-58-4
2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.
Formula:
C14H22O2
Purity:
97.11%
Color and Shape:
Pelletslargecrystals
Molecular weight:
222.32
Ref: TM-T7540
| 10g | 34.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Tepoxalin
CAS:103475-41-8
Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low …
Formula:
C20H20ClN3O3
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
385.84
Ref: TM-T7724
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 384.00 € | ||
| 50mg | 576.00 € | ||
| 100mg | 816.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
5-O-Demethylnobiletin
CAS:2174-59-6
5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.
Formula:
C20H20O8
Purity:
99.83% - ≥95%
Color and Shape:
Solid
Molecular weight:
388.37
Ref: TM-T5714
| 1mg | 64.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 357.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 739.00 € | ||
| 500mg | 1,613.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
FPL 62064
CAS:103141-09-9
FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 …
Formula:
C16H15N3O
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
265.31
Ref: TM-T8356
| 1mg | 39.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 191.00 € | ||
| 50mg | 287.00 € | ||
| 100mg | 430.00 € | ||
| 200mg | 600.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
ML351
CAS:847163-28-4
ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).
Formula:
C15H11N3O
Purity:
97.67%
Color and Shape:
Solid
Molecular weight:
249.27
Ref: TM-T21902
| 1mg | 52.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 736.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Linoleyl alcohol
CAS:506-43-4
Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl …
Formula:
C18H34O
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
266.469
Ref: TM-T9512
| 200mg | To inquire | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
3-Hydroxycoumarin
CAS:939-19-5
3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors
Formula:
C9H6O3
Purity:
98.32% - 99.91%
Color and Shape:
Solid
Molecular weight:
162.14
Ref: TM-T8002
| 100mg | 35.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
ML355
CAS:1532593-30-8
ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.
Formula:
C21H19N3O4S2
Purity:
98.2% - 99.26%
Color and Shape:
Solid
Molecular weight:
441.52
Ref: TM-T4347
| 1mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 477.00 € | ||
| 100mg | 732.00 € | ||
| 500mg | 1,468.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
11-Keto-β-boswellic acid
CAS:17019-92-0
11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent …
Formula:
C30H46O4
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
470.68
Ref: TM-TN1182
| 1mg | 59.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 207.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 517.00 € | ||
| 100mg | 733.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Terameprocol
CAS:24150-24-1
Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.
Formula:
C22H30O4
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
358.47
Ref: TM-T21746
| 10mg | 49.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 128.00 € | ||
| 100mg | 202.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Wedelolactone
CAS:524-12-9
Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and …
Formula:
C16H10O7
Purity:
98.07% - 99.76%
Color and Shape:
Solid
Molecular weight:
314.25
Ref: TM-T3384
| 1mg | 35.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 429.00 € | ||
| 500mg | 984.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
CAY10698
CAS:684236-01-9
CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).
Formula:
C17H17N3O4S2
Purity:
98.97%
Color and Shape:
Solid
Molecular weight:
391.46
Ref: TM-T8950
| 2mg | 39.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 362.00 € | ||
| 200mg | 511.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
U-73122
CAS:112648-68-7
U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
Formula:
C29H40N2O3
Purity:
96.73%
Color and Shape:
Solid Off-White
Molecular weight:
464.64
Ref: TM-T6243
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 230.00 € | ||
| 100mg | 421.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
N-Dehydroxyzileuton
Controlled ProductCAS:171370-49-3
Applications N-Dehydroxyzileuton is a pharmacologically inactive metabolite of Zileuton (Z420000), an inhibitor of 5-lipoxygenase that …
Formula:
C11H12N2OS
Color and Shape:
Neat
Molecular weight:
220.29
Ref: TR-D230150
| 50mg | 252.00 € | ||
| 500mg | 1,668.00 € |
Estimated delivery in United States, on Friday 15 Nov 2024
1,1-Bis(hydroxymethyl)cyclopropane
Controlled ProductCAS:39590-81-3
Applications 1,1-Bis(hydroxymethyl)cyclopropane is used in the synthesis of morphine alkaloids. It also serves as an …
Formula:
C5H10O2
Color and Shape:
Neat
Molecular weight:
102.13
Ref: TR-B445050
| 5g | 168.00 € | ||
| 25g | 436.00 € | ||
| 250g | 701.00 € |
Estimated delivery in United States, on Friday 15 Nov 2024
a-Boswellic Acid
Controlled ProductCAS:471-66-9
Applications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to …
Formula:
C30H48O3
Color and Shape:
Neat
Molecular weight:
456.70
Ref: TR-B676490
| 10mg | 542.00 € | ||
| 100mg | 2,152.00 € | ||
| 2500µg | 316.00 € |
Estimated delivery in United States, on Friday 15 Nov 2024
2,4-Dichlorobenzoyl Chloride
Controlled ProductCAS:89-75-8
Applications 2,4-Dichlorobenzoyl Chloride is a reactant used in the synthesis of aroyl(sulfamoylphenyl)thiourea derivatives as 15-lipoxygenase …
Formula:
C7H3Cl3O
Color and Shape:
Neat
Molecular weight:
209.46
Ref: TR-D431715
| 25g | 212.00 € | ||
| 100g | 284.00 € | ||
| 250g | 550.00 € |
Estimated delivery in United States, on Tuesday 26 Nov 2024
Dimethyl (2-Oxoheptyl)phosphonate
Controlled ProductCAS:36969-89-8
Applications Dimethyl (2-Oxoheptyl)phosphonate is a useful synthetic intermediate, and is used as a reagent to …
Formula:
C9H19O4P
Color and Shape:
Yellow
Molecular weight:
222.22
Ref: TR-D476570
| 1g | 341.00 € | ||
| 5g | 1,119.00 € | ||
| 500mg | 211.00 € |
Estimated delivery in United States, on Tuesday 26 Nov 2024
