Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 134 products for "Lipoxygenase".
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Atreleuton
CAS:Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.3715(S)-HETrE
CAS:15(S)-HETrE, a 15-lipoxygenated DGLA derivative, inhibits human 5-LO with IC50 of 4.6μM; 5% as effective in RBL cells.Formula:C20H34O3Color and Shape:SolidMolecular weight:322.48LY 269415
CAS:LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.Formula:C19H28N2O2SColor and Shape:SolidMolecular weight:348.5AHR-5333 mandelate
CAS:AHR-5333 mandelate is an anti-allergy agent preventing anaphylaxis and skin hypersensitivity; inhibits 5-HETE, LTB4, LTC4 synthesis.Formula:C38H41F2NO7Color and Shape:SolidMolecular weight:661.7413(S)-HpOTrE(γ)
CAS:13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.Formula:C18H30O4Color and Shape:SolidMolecular weight:310.43MLS000536924
CAS:MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Formula:C16H15N3SColor and Shape:SolidMolecular weight:281.38BI-L 357
CAS:BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formula:C18H18O4SColor and Shape:SolidMolecular weight:330.4Leukotriene A3 methyl ester
CAS:LTA3, made from 5,8,11-eicosatrienoic acid via 5-LO, is unstable; its stable methyl ester form turns into free acid when needed.Formula:C21H34O3Color and Shape:SolidMolecular weight:334.49L 652343
CAS:L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.Formula:C22H14F3NO2S2Color and Shape:SolidMolecular weight:445.48Setileuton tosylate
CAS:Setileuton (MK0633): a potent 5-lipoxygenase inhibitor, researched for asthma and atherosclerosis treatment.Formula:C29H25F4N3O7SColor and Shape:SolidMolecular weight:635.58PF-4191834
CAS:PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Formula:C22H23N3O2SPurity:99.83% - 99.98%Color and Shape:White SolidMolecular weight:393.5Ref: TM-T16503
5mg50.00€1mL*10mM (DMSO)55.00€10mg79.00€25mg146.00€50mg245.00€100mg355.00€500mg772.00€LP117
CAS:LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).Formula:C21H23ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:430.95Fenleuton
CAS:Fenleuton is a 5-lipoxygenase inhibitor.Formula:C17H15FN2O3Purity:98%Color and Shape:SolidMolecular weight:314.31L 656224
CAS:L 656224 is a 5-LO inhibitor.Formula:C20H21ClO3Purity:98%Color and Shape:SolidMolecular weight:344.83AHR-5333
CAS:AHR-5333 an antiallergy agent.Formula:C30H33F2NO4Purity:98%Color and Shape:SolidMolecular weight:509.58LY 221068
CAS:LY 221068 is a potent antioxidant with anti-inflammatory activity.Formula:C20H30N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.53Fluindione
CAS:Fluindione is a hematologic drug.Formula:C15H9FO2Color and Shape:SolidMolecular weight:240.23YS-121
CAS:YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).Formula:C20H26ClN3O2SColor and Shape:SolidMolecular weight:407.96Lipoxygenin
CAS:Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.Formula:C24H22N2O4Color and Shape:SolidMolecular weight:402.44ICI 211965
CAS:ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).Formula:C24H23NO2SPurity:98%Color and Shape:SolidMolecular weight:389.51
