Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 133 products of "Lipoxygenase"
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Nafazatrom
CAS:Nafazatrom: pyrazolinone lipoxygenase inhibitor, anticancer & antithrombotic, boosts PGI2, reduces arrhythmias.Formula:C16H16N2O2Color and Shape:SolidMolecular weight:268.31LY 221068
CAS:LY 221068 is a potent antioxidant with anti-inflammatory activity.Formula:C20H30N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.5315(S)-HETrE
CAS:15(S)-HETrE, a 15-lipoxygenated DGLA derivative, inhibits human 5-LO with IC50 of 4.6μM; 5% as effective in RBL cells.Formula:C20H34O3Color and Shape:SolidMolecular weight:322.48AHR-5333 mandelate
CAS:AHR-5333 mandelate is an anti-allergy agent preventing anaphylaxis and skin hypersensitivity; inhibits 5-HETE, LTB4, LTC4 synthesis.Formula:C38H41F2NO7Color and Shape:SolidMolecular weight:661.7413(S)-HpOTrE(γ)
CAS:13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.Formula:C18H30O4Color and Shape:SolidMolecular weight:310.43Leukotriene A3 methyl ester
CAS:LTA3, made from 5,8,11-eicosatrienoic acid via 5-LO, is unstable; its stable methyl ester form turns into free acid when needed.Formula:C21H34O3Color and Shape:SolidMolecular weight:334.49Setileuton tosylate
CAS:Setileuton (MK0633): a potent 5-lipoxygenase inhibitor, researched for asthma and atherosclerosis treatment.Formula:C29H25F4N3O7SColor and Shape:SolidMolecular weight:635.58Atreleuton
CAS:Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37YS-121
CAS:YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).Formula:C20H26ClN3O2SColor and Shape:SolidMolecular weight:407.96LP117
CAS:LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).Formula:C21H23ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:430.95Fenleuton
CAS:Fenleuton is a 5-lipoxygenase inhibitor.Formula:C17H15FN2O3Purity:98%Color and Shape:SolidMolecular weight:314.31L 656224
CAS:L 656224 is a 5-LO inhibitor.Formula:C20H21ClO3Purity:98%Color and Shape:SolidMolecular weight:344.83RG 6866
CAS:RG 6866 is a inhibitor of 5-lipoxygenase.Formula:C16H17NO3Purity:98%Color and Shape:SolidMolecular weight:271.31ICI 211965
CAS:ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).Formula:C24H23NO2SPurity:98%Color and Shape:SolidMolecular weight:389.51EP6
CAS:EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.Formula:C24H30N4OPurity:98%Color and Shape:SolidMolecular weight:390.52HZ52
CAS:HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.Formula:C24H26ClN3O2SColor and Shape:SolidMolecular weight:456Cgp 8065
CAS:Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.Formula:C16H15N3O4S2Color and Shape:SolidMolecular weight:377.44Fluindione
CAS:Fluindione is a hematologic drug.Formula:C15H9FO2Color and Shape:SolidMolecular weight:240.23Lipoxygenin
CAS:Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.Formula:C24H22N2O4Color and Shape:SolidMolecular weight:402.44BI-L 357
CAS:BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formula:C18H18O4SColor and Shape:SolidMolecular weight:330.4
