Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 133 products of "Lipoxygenase"
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FPL 62064
CAS:FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFormula:C16H15N3OPurity:98.79%Color and Shape:SolidMolecular weight:265.31Ref: TM-T8356
2mg35.00€5mg52.00€10mg86.00€25mg136.00€50mg198.00€100mg298.00€200mg414.00€1mL*10mM (DMSO)73.00€ML351
CAS:ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Formula:C15H11N3OPurity:97.67%Color and Shape:SolidMolecular weight:249.27Ref: TM-T21902
1mg50.00€5mg105.00€10mg167.00€25mg334.00€50mg505.00€100mg713.00€1mL*10mM (DMSO)117.00€Linoleyl alcohol
CAS:Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].Formula:C18H34OPurity:98.12%Color and Shape:SolidMolecular weight:266.463-Hydroxycoumarin
CAS:3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFormula:C9H6O3Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:162.1411-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Ref: TM-TN1182
1mg57.00€5mg130.00€10mg200.00€25mg338.00€50mg497.00€100mg710.00€1mL*10mM (DMSO)133.00€Terameprocol
CAS:Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25Ref: TM-T3384
1mg34.00€5mg71.00€10mg109.00€25mg175.00€50mg314.00€100mg414.00€500mg954.00€1mL*10mM (DMSO)50.00€CAY10698
CAS:CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).Formula:C17H17N3O4S2Purity:98.97%Color and Shape:SolidMolecular weight:391.46Ref: TM-T8950
2mg38.00€5mg52.00€10mg88.00€25mg161.00€50mg243.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)62.00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purity:97.50%Color and Shape:Solid Off-WhiteMolecular weight:464.64a-Boswellic Acid
CAS:Controlled ProductApplications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);Formula:C30H48O3Color and Shape:NeatMolecular weight:456.74-(2-Methylpropyl)benzenemethanol
CAS:Controlled ProductFormula:C11H16OColor and Shape:NeatMolecular weight:164.24MLS000536924
CAS:MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Formula:C16H15N3SColor and Shape:SolidMolecular weight:281.38tHGA
CAS:tHGA is a potent inhibitor of lipoxygenase.Formula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38L 652343
CAS:L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.Formula:C22H14F3NO2S2Color and Shape:SolidMolecular weight:445.48AHR-5333
CAS:AHR-5333 an antiallergy agent.Formula:C30H33F2NO4Purity:98%Color and Shape:SolidMolecular weight:509.58PF-4191834
CAS:PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.Formula:C22H23N3O2SPurity:99.83% - 99.98%Color and Shape:SolidMolecular weight:393.5Ref: TM-T16503
5mg52.00€10mg84.00€25mg155.00€50mg259.00€100mg375.00€500mg815.00€1mL*10mM (DMSO)58.00€Texasin
CAS:Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.Formula:C16H12O5Purity:98%Color and Shape:SolidMolecular weight:284.26L-651392
CAS:L-651392 is an inhibitor of leukotriene.Formula:C14H10BrNO3SColor and Shape:SolidMolecular weight:352.2SB 210661
CAS:SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Formula:C16H14F2N2O4Purity:98%Color and Shape:SolidMolecular weight:336.29Enazadrem
CAS:Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
Formula:C18H25N3OPurity:98%Color and Shape:SolidMolecular weight:299.41
