Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 134 products for "Lipoxygenase".
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3-Hydroxycoumarin
CAS:3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFormula:C9H6O3Purity:99.5% - 99.77%Color and Shape:SolidMolecular weight:162.14ML355
CAS:ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.Formula:C21H19N3O4S2Purity:97.17% - 98.02%Color and Shape:SolidMolecular weight:441.52Ref: TM-T4347
1mg43.00€5mg92.00€1mL*10mM (DMSO)96.00€10mg152.00€25mg281.00€50mg462.00€100mg708.00€200mg964.00€11-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68Ref: TM-TN1182
1mg57.00€5mg130.00€1mL*10mM (DMSO)133.00€10mg200.00€25mg338.00€50mg497.00€100mg710.00€Terameprocol
CAS:Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formula:C22H30O4Purity:99.38%Color and Shape:SolidMolecular weight:358.47Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25Ref: TM-T3384
1mg34.00€1mL*10mM (DMSO)50.00€5mg71.00€10mg109.00€25mg175.00€50mg314.00€100mg414.00€500mg954.00€CAY10698
CAS:CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).Formula:C17H17N3O4S2Purity:98.97%Color and Shape:SolidMolecular weight:391.46Ref: TM-T8950
2mg38.00€5mg52.00€1mL*10mM (DMSO)62.00€10mg88.00€25mg161.00€50mg243.00€100mg355.00€200mg502.00€U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purity:97.50% - 98.66%Color and Shape:White SolidMolecular weight:464.64a-Boswellic Acid
CAS:Controlled ProductApplications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);Formula:C30H48O3Color and Shape:NeatMolecular weight:456.7Oxyberberin
CAS:Controlled ProductApplications Oxyberberin is a naturally occurring isoquinoline alkaloid shown to inhibit lipoxygenase and provide antioxidant activity.
References Misík V. et al.: Planta. Med., 61, 372 (1995)Formula:C20H17NO5Color and Shape:NeatMolecular weight:351.35Golocdacimab
CAS:Golocdacimab (anti-LOX-1 mAb) targets LOX-1, with potential applications for type 2 diabetes complications and preventing HAE attacks.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDa1-Stearoyl-2-Oleoyl-3-Linoleoyl-rac-glycerol
CAS:1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol is a triacylglycerol consisting of stearic acid, oleic acid, and linoleic acid esterified at the sn-1, sn-2, and sn-3 positions, respectively. This compound is present in peanut and soybean oils as well as in ostrich and emu oils. Additionally, it serves as a substrate for soybean lipoxygenase in cell-free assays.Formula:C57H104O6Color and Shape:SolidMolecular weight:885.434-(2-Methylpropyl)benzenemethanol
CAS:Controlled ProductFormula:C11H16OColor and Shape:NeatMolecular weight:164.24Cgp 8065
CAS:Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.Formula:C16H15N3O4S2Color and Shape:SolidMolecular weight:377.44SB 210661
CAS:SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Formula:C16H14F2N2O4Purity:98%Color and Shape:SolidMolecular weight:336.29Enazadrem
CAS:Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.Formula:C18H25N3OPurity:98%Color and Shape:SolidMolecular weight:299.412-TEDC
CAS:2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.Formula:C16H13NO4SPurity:99.97%Color and Shape:SolidMolecular weight:315.34MLS000536924
CAS:MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Formula:C16H15N3SColor and Shape:SolidMolecular weight:281.38E 3040
CAS:E 3040 is an oral dual inhibitor of 5-lipoxygenase and thromboxane synthase with anti-inflammatory activity.Formula:C16H17N3OSColor and Shape:White SolidMolecular weight:299.39Nafazatrom
CAS:Nafazatrom: pyrazolinone lipoxygenase inhibitor, anticancer & antithrombotic, boosts PGI2, reduces arrhythmias.Formula:C16H16N2O2Color and Shape:SolidMolecular weight:268.31Atreleuton
CAS:Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37
