5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Found 1025 products of "5-HT Receptor"
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Flopropione
CAS:Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.Formula:C9H10O4Purity:99.93%Color and Shape:SolidMolecular weight:182.17Levodropropizine
CAS:Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.Formula:C13H20N2O2Purity:99.87% - 99.93%Color and Shape:White Or Off White Crystalline PowderMolecular weight:236.31Alverine citrate
CAS:Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.Formula:C26H35NO7Purity:98.53% - 99.43%Color and Shape:CoaMolecular weight:473.57Lintopride HCl
CAS:Lintopride HCl is a 5HT-4 antagonist.Formula:C14H20Cl2N4O2Purity:98.42% - 98.81%Color and Shape:SoildMolecular weight:347.24Citalopram hydrobromide
CAS:Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, therebyFormula:C20H22BrFN2OPurity:99.81%Color and Shape:White Crystalline PowderMolecular weight:405.304BF-1
CAS:BF-1 blocks 5-HT2B, may prevent migraines by hindering BW723C86/mCPP in guinea pigs.Formula:C22H25NO2SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:367.50Amisulpride
CAS:Amisulpride (Solian/Deniban), a dopamine antagonist antipsychotic, treats psychosis and schizophrenia in Europe/Australia, not in the US.Formula:C17H27N3O4SPurity:99.97% - 99.99%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:369.48Carvedilol EP IMpurity E
CAS:Carvedilol EP IMpurity E (Carvedilol USP E) is used as a pharmaceutical intermediate.Formula:C9H14ClNO2Purity:99.53%Color and Shape:White To Almost White Solid CrystallineMolecular weight:203.666Tropanserin
CAS:Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.Formula:C17H23NO2Purity:99.74%Color and Shape:SolidMolecular weight:273.37Cloperastine hydrochloride
CAS:Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.Formula:C20H25Cl2NOPurity:97.74% - 99.42%Color and Shape:SolidMolecular weight:366.33Fluoxetine
CAS:Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Formula:C17H18F3NOPurity:99.07% - 99.28%Color and Shape:SolidMolecular weight:309.33Quetiapine
CAS:Quetiapine treats schizophrenia and bipolar I, targeting serotonin, dopamine, and adrenoreceptor subtypes, plus H1 histamine receptor.Formula:C21H25N3O2SPurity:99.14% - 99.63%Color and Shape:White To Off-White Crystalline PowderMolecular weight:383.51Cloroperone
CAS:Cloroperone has anxiolytic activity and may be used in the study of neurologic disorders.Formula:C22H23ClFNO2Purity:98.40%Color and Shape:SoildMolecular weight:387.88Fluoxetine hydrochloride
CAS:Fluoxetine HCl (Lilly110140), a selective serotonin reuptake inhibitor (SSRI), is an antidepressant with fewer side effects.Formula:C17H19ClF3NOPurity:99.6% - 99.98%Color and Shape:White To Off-White Crystalline Solid White To Off-White PowderMolecular weight:345.787Zolmitriptan
CAS:Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.Formula:C16H21N3O2Purity:99.69% - 99.91%Color and Shape:White Or Kind Of White PowderMolecular weight:287.36Frovatriptan succinate hydrate
CAS:Frovatriptan treats all migraine types, nausea, vomiting, light/sound sensitivity, and prevents menstrual migraines; it targets 5-HT1B/D and 5-HT7 receptors.Formula:C18H25N3O6Purity:99.66%Color and Shape:SolidMolecular weight:379.41Cisapride
CAS:Cisapride (R 51619), a 5-HT4 agonist, enhances gut peristalsis and gastric emptying, reduces reflux.Formula:C23H29ClFN3O4Purity:99.77%Color and Shape:White To Slightly Biege Powder SolidMolecular weight:465.95Ref: TM-T1291
5mg44.00€10mg56.00€25mg73.00€50mg94.00€100mg128.00€200mg222.00€500mg374.00€1mL*10mM (DMSO)52.00€Blonanserin
CAS:Blonanserin (AD-5423), approved in Japan (2008), is an atypical antipsychotic with fewer side effects like EPS, sedation, or hypotension.Formula:C23H30FN3Purity:99.85%Color and Shape:SolidMolecular weight:367.50Protriptyline hydrochloride
CAS:Protriptyline HCl: a tricyclic antidepressant that increases norepinephrine and serotonin levels and has anticholinergic effects.Formula:C19H21N·HClPurity:98.54% - 99.98%Color and Shape:SolidMolecular weight:299.84Olanzapine
CAS:Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Formula:C17H20N4SPurity:99.86% - ≥95%Color and Shape:Yellowish Crystalline PowderMolecular weight:312.43Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43Agomelatine
CAS:Agomelatine (Valdoxan), like melatonin, boosts mood by targeting melatonin and 5-HT2C receptors.Formula:C15H17NO2Purity:99.92%Color and Shape:White SolidMolecular weight:243.30Azatadine dimaleate
CAS:Azatadine dimaleate (SCH10649) is an inhibitor for histamine（IC50=6.5 nM） and cholinergic（IC50=10 nM）.
Formula:C28H30N2O8Purity:99.7% - >99.99%Color and Shape:PowderMolecular weight:522.55RS102895 hydrochloride
CAS:RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).Formula:C21H22ClF3N2O2Purity:98.95%Color and Shape:SolidMolecular weight:426.86Gevotroline
CAS:Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.Formula:C19H20FN3Purity:99.45%Color and Shape:SolidMolecular weight:309.38ECPLA
CAS:ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formula:C21H25N3OColor and Shape:SolidMolecular weight:335.44SB 216641
CAS:SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.Formula:C28H30N4O4Purity:98.09%Color and Shape:SolidMolecular weight:486.56(+)-OSU 6162
CAS:(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Formula:C15H23NO2SPurity:98.19%Color and Shape:SoildMolecular weight:281.41Ref: TM-T60027
1mg73.00€5mg146.00€10mg208.00€25mg319.00€50mg447.00€100mg600.00€200mg808.00€1mL*10mM (DMSO)155.00€MR33317
MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.Formula:C22H28ClN3O2Molecular weight:401.187Minesapride
CAS:Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.
Formula:C21H31ClN4O5Purity:99.85% - 99.88%Color and Shape:SolidMolecular weight:454.95Cinanserin hydrochloride
CAS:Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.Formula:C20H25ClN2OSPurity:99.57%Color and Shape:SolidMolecular weight:376.94Neocarzinostatin
CAS:Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Purity:98%Color and Shape:SolidMolecular weight:N/AIloperidone metabolite P95
CAS:Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Formula:C23H25FN2O5Color and Shape:SolidMolecular weight:428.465-HT2C agonist-4
CAS:Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Formula:C24H25N5OColor and Shape:SolidMolecular weight:399.495-HT6 inverse agonist 1
CAS:5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formula:C22H22Cl2FN3O3SColor and Shape:SolidMolecular weight:498.4ALEPH hydrochloride
CAS:ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.Formula:C12H20ClNO2SColor and Shape:SolidMolecular weight:277.81Donitriptan hydrochloride
CAS:Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormula:C23H26ClN5O2Purity:99.8% - 99.86%Color and Shape:SolidMolecular weight:439.94Ref: TM-T21666
2mg40.00€5mg49.00€10mg64.00€25mg135.00€50mg240.00€100mg339.00€200mg439.00€500mgTo inquireSB 699551
CAS:SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.Formula:C34H45N3OPurity:99.83%Color and Shape:SoildMolecular weight:511.74Ref: TM-T23325L
1mg190.00€5mg471.00€10mg662.00€25mg1,036.00€50mg1,429.00€100mg1,821.00€200mg2,489.00€PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Color and Shape:Solidmeta-Fluoxetine (hydrochloride)
CAS:meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formula:C17H19ClF3NOColor and Shape:SolidMolecular weight:345.79Lisuride maleate
CAS:Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.Formula:C24H30N4O5Purity:99.85%Color and Shape:SolidMolecular weight:454.52Ref: TM-T8775
1mg204.00€5mg627.00€10mg898.00€25mg1,346.00€50mg1,745.00€100mg2,382.00€1mL*10mM (DMSO)627.00€Asenapine citrate
CAS:Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Formula:C23H24ClNO8Color and Shape:SolidMolecular weight:477.89(R,R)-Palonosetron Hydrochloride
CAS:(R,R)-Palonosetron Hydrochloride is the active enantiomer of PalonosetronFormula:C19H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:332.875-MeO-pyr-T
CAS:5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formula:C15H20N2OColor and Shape:SolidMolecular weight:244.335-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Formula:C25H29ClN4O2SColor and Shape:SolidMolecular weight:485.045-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formula:C24H26N4O2SColor and Shape:SolidMolecular weight:434.55(-)-Eseroline fumarate
CAS:(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.Formula:C17H22N2O5Color and Shape:SolidMolecular weight:334.37Paynantheine
CAS:Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.Formula:C23H28N2O4Color and Shape:SolidMolecular weight:396.48LY 344864 racemate
CAS:LY 344864 racemate is a 5-HT1F receptor agonist.Formula:C21H22FN3OPurity:99.75%Color and Shape:SoildMolecular weight:351.42Imipramine N-oxide
CAS:Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.Formula:C19H24N2OPurity:99.80%Color and Shape:SolidMolecular weight:296.41Ref: TM-T74205
1mg72.00€5mg157.00€10mg241.00€25mg409.00€50mg565.00€100mg794.00€1mL*10mM (DMSO)167.00€
