5-HT Receptor
5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.
Found 940 products of "5-HT Receptor"
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Geissoschizine methyl ether
CAS:<p>Geissoschizine methyl ether: an alkaloid from Uncaria hook, key in Yokukansan, impacts mood and social behavior enhancing serotonin activity.</p>Formula:C22H26N2O3Purity:99.24% - 99.68%Color and Shape:SolidMolecular weight:366.45Tropisetron
CAS:<p>Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.</p>Formula:C17H20N2O2Purity:99.68%Color and Shape:White SolidMolecular weight:284.35Sevoflurane
CAS:<p>Sevoflurane (Fluoromethyl), a noncompetitive inhibitor of 5-HT3 receptor, acts as a low-soluble inhalation anesthetics.</p>Formula:C4H3F7OPurity:98%Color and Shape:Less Oil Colorless OilMolecular weight:200.05SB399885
CAS:<p>SB399885 is a potent, brain-penetrant, oral SR-6 antagonist with 200-fold selectivity for SR-6 receptors.</p>Formula:C18H21Cl2N3O4SPurity:98.94%Color and Shape:SolidMolecular weight:446.35LY334370
CAS:<p>LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM</p>Formula:C21H22FN3OPurity:99.32%Color and Shape:SolidMolecular weight:351.42Lurasidone
CAS:<p>Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6</p>Formula:C28H36N4O2SPurity:99.78% - 99.91%Color and Shape:SolidMolecular weight:492.68Eltoprazine
CAS:<p>Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.</p>Formula:C12H16N2O2Color and Shape:SolidMolecular weight:220.27Perospirone
CAS:<p>Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors.</p>Formula:C23H30N4O2SPurity:99.23%Color and Shape:White PowderMolecular weight:426.57ARC-239
CAS:<p>ARC-239 is an agonist of α2-adrenergic receptor.</p>Formula:C24H29N3O3Color and Shape:SolidMolecular weight:407.51VUF 10166
CAS:<p>VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.</p>Formula:C13H15ClN4Purity:99.66%Color and Shape:SolidMolecular weight:262.74(S)-Amisulpride
CAS:<p>(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist.</p>Formula:C17H27N3O4SPurity:98.38%Color and Shape:SolidMolecular weight:369.48Puerarin
CAS:<p>Puerarin (Kakonein), also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.</p>Formula:C21H20O9Purity:98.90% - 99.21%Color and Shape:Yellow Brown Fine PowderMolecular weight:416.38Nelotanserin
CAS:<p>Nelotanserin (APD125): strong 5-HT2A inverse agonist (IC50: 1.7 nM), moderate 5-HT2C (79 nM), weak 5-HT2B (791 nM).</p>Formula:C18H15BrF2N4O2Purity:98.42% - 99.88%Color and Shape:SolidMolecular weight:437.24S 14506 HCl
CAS:<p>S 14506 HCl: Strong 5-HT1A agonist; pKi - 9.0 (5-HT1A), 6.6 (5-HT1B/C), <6.0 (5-HT3).</p>Formula:C24H26FN3O2Color and Shape:SolidMolecular weight:407.48RU 24969 free base
CAS:<p>RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.</p>Formula:C14H16N2OPurity:97.38%Color and Shape:SolidMolecular weight:228.29Azaphen
CAS:<p>Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.</p>Formula:C16H21Cl2N5OPurity:97.62%Color and Shape:SolidMolecular weight:370.28Alosetron (Hydrochloride(1:X))
CAS:<p>Alosetron Hydrochloride is a selective 5-HT3 antagonist for treating IBS.</p>Formula:C17H18ClN4OColor and Shape:SolidMolecular weight:329.11691(E)-3,4,5-Trimethoxycinnamic acid
CAS:<p>(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.</p>Formula:C12H14O5Purity:99.83%Color and Shape:SolidMolecular weight:238.24Loxapine hydrochloride
CAS:<p>Loxapine hydrochloride, an oral anti-psychotic, inhibits dopamine and blocks 5-HT receptors.</p>Formula:C18H19Cl2N3OColor and Shape:SolidMolecular weight:364.27Cinanserin
CAS:<p>Cinanserin is a serotonin 5-HT2 antagonist.</p>Formula:C20H24N2OSColor and Shape:SolidMolecular weight:340.48Serotonin hydrochloride
CAS:<p>Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (</p>Formula:C10H13ClN2OPurity:98.05% - 99.93%Color and Shape:White To Cream PowderMolecular weight:212.676WAY-100635 Monomaleate
CAS:<p>WAY-100635 maleate is a selective 5-hydroxytryptamine 1A receptor antagonist with an IC50 value of 0.91 nM and a Ki value of 0.39 nM.</p>Formula:C25H34N4O2·C4H4O4Purity:98.44% - 99.46%Color and Shape:SolidMolecular weight:538.64Piboserod
CAS:<p>Piboserod (SB-207266) (SB 207266) is a selective 5-HT(4) receptor antagonist.</p>Formula:C22H31N3O2Purity:97.21% - 99.49%Color and Shape:SolidMolecular weight:369.5Almotriptan Malate
CAS:<p>Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.</p>Formula:C17H25N3O2S·C4H6O5Purity:99.95%Color and Shape:Pale Yellow SolidMolecular weight:469.55Risperidone hydrochloride
CAS:<p>Risperidone hydrochloride blocks 5-HT2, inhibits P-glycoprotein, and antagonizes D2 receptors (Ki: 5-HT2A - 4.8 nM, D2 - 5.9 nM).</p>Formula:C23H28ClFN4O2Color and Shape:SolidMolecular weight:446.95Ocaperidone
CAS:<p>Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.</p>Formula:C24H25FN4O2Purity:99.33%Color and Shape:SolidMolecular weight:420.48Phenylbiguanide
CAS:<p>Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)</p>Formula:C8H11N5Purity:99.54%Color and Shape:SolidMolecular weight:177.21Sumatriptan hydrochloride
CAS:<p>Sumatriptan hydrochloride (GR 43175), an oral 5-HT1 receptor agonist, treats migraines; Ki: 5-HT1D - 17 nM, 5-HT1B - 27 nM, 5-HT1A - 100 nM.</p>Formula:C14H22ClN3O2SColor and Shape:SolidMolecular weight:331.86Escitalopram Oxalate
CAS:<p>Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.</p>Formula:C22H23FN2O5Purity:97.39% - 99.73%Color and Shape:White SolidMolecular weight:414.43BRL-15572 hydrochloride
CAS:<p>BRL-15572 hydrochloride: selective h5-HT1D antagonist with high affinity; useful for studying h5-HT1D responses.</p>Formula:C25H28Cl2N2OColor and Shape:SolidMolecular weight:443.414i
CAS:<p>4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system.</p>Formula:C16H12ClN3OPurity:99.49%Color and Shape:SolidMolecular weight:297.74SB 242084
CAS:<p>SB 242084 dihydrochloride hydrate is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.</p>Formula:C21H19ClN4O2Purity:99.75% - ≥98%Color and Shape:SolidMolecular weight:394.85PNU 22394 hydrochloride
CAS:<p>PNU 22394 hydrochloride is a 5-HT2C agonist and partial 5-HT2A/5-HT2B agonist</p>Formula:C13H17ClN2Purity:97.83%Color and Shape:SolidMolecular weight:236.74Amitriptyline
CAS:<p>Amitriptyline: a tricyclic antidepressant used for depression and neuropathic pain.</p>Formula:C20H23NPurity:98.24% - 99.64%Color and Shape:Crystals SolidMolecular weight:277.4Pirenperone
CAS:<p>Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action.</p>Formula:C23H24FN3O2Purity:99.2%Color and Shape:SolidMolecular weight:393.45Quipazine
CAS:<p>Quipazine: 5-HT agonist, Ki 1.4 nM at 5-HT3R, anti-SARS-CoV-2 (EC50 31.64 μM), for neurological research.</p>Formula:C13H15N3Color and Shape:SolidMolecular weight:213.28SR 57227 hydrochloride
CAS:<p>SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.</p>Formula:C10H14ClN3·HClPurity:99.89%Color and Shape:SolidMolecular weight:248.15Ramosetron
CAS:<p>Ramosetron 是一种血清素 5-HT3 受体拮抗剂，用于治疗恶心和呕吐。它被认为比其他一代 5-HT3 拮抗剂如昂丹司琼具有更高的效力和更长的止吐作用。它还适用于治疗“男性以腹泻为主的肠易激综合征”。它仅获准在日本和选定的东南亚国家使用。</p>Formula:C17H17N3OPurity:98.84%Color and Shape:SolidMolecular weight:279.34F-15599
CAS:<p>F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).</p>Formula:C19H21ClF2N4OPurity:98.72%Color and Shape:SolidMolecular weight:394.857-Amino-4-(trifluoromethyl)coumarin
CAS:<p>7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.</p>Formula:C10H6F3NO2Purity:97.31% - 97.84%Color and Shape:Yellow PowderMolecular weight:229.16Tiprenolol
CAS:<p>Tiprenolol is a beta adrenergic receptor antagonist.[1]</p>Formula:C13H21NO2SPurity:99.43%Color and Shape:SolidMolecular weight:255.38BMY 7378 dihydrochloride
CAS:<p>BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.</p>Formula:C22H33Cl2N3O3Purity:97.32% - 99.08%Color and Shape:SolidMolecular weight:458.42Tandospirone hydrochloride
CAS:<p>Tandospirone (SM-3997) HCl: potent 5-HT1A partial agonist; Ki: 27 nM; anxiolytic, antidepressant, for CNS disorder research.</p>Formula:C21H30ClN5O2Color and Shape:SolidMolecular weight:419.95γ-Mangostin
CAS:<p>Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.</p>Formula:C23H24O6Purity:98.55% - 99.08%Color and Shape:SolidMolecular weight:396.43Xanthotoxol
CAS:<p>Xanthotoxol (Psoralen) is a bioactive furocoumarin with anti-inflammatory, antioxidant, 5-HT antagonist, and neuroprotective properties.</p>Formula:C11H6O4Purity:99.97%Color and Shape:SolidMolecular weight:202.16TG6-10-1
CAS:<p>TG6-10-1 is an EP2 antagonist.</p>Formula:C23H23F3N2O4Purity:99.66% - ≥95%Color and Shape:SolidMolecular weight:448.43Cariprazine
CAS:<p>Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate</p>Formula:C21H32Cl2N4OPurity:99.68% - 99.87%Color and Shape:SolidMolecular weight:427.41PRX-07034 hydrochloride
CAS:<p>PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and decreases body weight in rodents.</p>Formula:C21H29Cl2N3O4SPurity:98.5%Color and Shape:SolidMolecular weight:490.44Aripiprazole monohydrate
CAS:<p>Aripiprazole (OPC-14597) is a potent D2 partial agonist and inverse agonist of 5-HT2 receptors, used for schizophrenia and COVID-19 studies.</p>Formula:C23H29Cl2N3O3Color and Shape:SolidMolecular weight:466.4MDL 100009
CAS:<p>MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.</p>Formula:C22H28FNO3Purity:98.96%Color and Shape:SolidMolecular weight:373.46
