Beta Amyloid
Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.
Found 231 products of "Beta Amyloid"
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Trontinemab
CAS:Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).Purity:96.77% - 99%Color and Shape:LiquidMolecular weight:194.25 kDaBSB
CAS:BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.Formula:C24H17BrO6Purity:95.53%Color and Shape:SolidMolecular weight:481.29δ-secretase inhibitor 11
CAS:δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.Formula:C10H12N4O2Purity:99.84%Color and Shape:SolidMolecular weight:220.23C18 L-erythro Ceramide (d18:1/18:0)
CAS:C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.Formula:C36H71NO3Color and Shape:SolidMolecular weight:565.95TH-237A
CAS:TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.Formula:C18H17F2NO3Purity:98%Color and Shape:SolidMolecular weight:333.335AZD4694
CAS:Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.Formula:C14H11FN2O2Color and Shape:SolidMolecular weight:258.25(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Formula:C27H27FN2O4Purity:98.27%Color and Shape:SolidMolecular weight:462.51Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Formula:C6H10CuN6S2Purity:99.21%Color and Shape:SolidMolecular weight:293.86Ref: TM-T40792
1mg37.00€5mg77.00€1mL*10mM (DMSO)82.00€10mg119.00€25mg263.00€50mg447.00€100mg749.00€200mg1,017.00€Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Formula:C9H8ClF6NO3S2Color and Shape:SolidMolecular weight:391.74Simufilam hydrochloride
CAS:Simufilam is an oral, low-toxicity FLNA activator for Alzheimer's research, fixing FLNA structure and reducing pathology.Formula:C15H22ClN3OColor and Shape:SolidMolecular weight:295.81Edonerpic maleate
CAS:Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).Formula:C20H25NO6SPurity:98.24%Color and Shape:SolidMolecular weight:407.48Semax acetate(80714-61-0 free base)
CAS:Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.Formula:C39H55N9O12SPurity:99.46%Color and Shape:SolidMolecular weight:873.98Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Formula:C6H7NO2SPurity:99.42% - 99.99%Color and Shape:White Crystalline PowderMolecular weight:157.19JLK6
CAS:JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signallingFormula:C10H8ClNO3Purity:96.50%Color and Shape:SolidMolecular weight:225.63Ref: TM-T21890
1mg84.00€5mg152.00€1mL*10mM (DMSO)160.00€10mg212.00€25mg354.00€50mg504.00€100mg685.00€200mg888.00€β-amyloid 1-11 acetate(190436-05-6 free base)
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Formula:C58H80N16O24Purity:>99.99%Color and Shape:SolidMolecular weight:1385.37Aftin-4
CAS:Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.Formula:C20H28N6OPurity:98.51%Color and Shape:SolidMolecular weight:368.48GSNKGAIIGLM(131602-53-4(free base))
GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide.Formula:C49H83F6N13O18SPurity:>99.99%Color and Shape:SolidMolecular weight:1288.32Ref: TM-T7680
1mg84.00€2mg133.00€5mg197.00€10mg314.00€1mL*10mM (DMSO)479.00€25mg530.00€50mg757.00€100mg1,044.00€Azeliragon HCl
CAS:Azeliragon: potent oral RAGE inhibitor, blocks Alzheimer's-linked amyloid brain entry.Formula:C32H40Cl3N3O2Color and Shape:SolidMolecular weight:605.04Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Formula:C8H10NO6PPurity:97.52%Color and Shape:SolidMolecular weight:247.14Frentizole
CAS:Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interactionFormula:C15H13N3O2SPurity:99.82%Color and Shape:SolidMolecular weight:299.35PE859
CAS:PE859 is a potent inhibitor of both tau and Aβ aggregation.Formula:C28H24N4O2Purity:98.8% - 99.09%Color and Shape:SolidMolecular weight:448.52Dihydroergocristine mesylate
CAS:DHEC mesylate is a vasodilator and α-adrenergic antagonist used for vascular dementia and as a geroprotector.Formula:C36H45N5O8SPurity:98.9% - 99.79%Color and Shape:SolidMolecular weight:707.84PBD-150
CAS:PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)Formula:C15H20N4O2SPurity:99.68%Color and Shape:SolidMolecular weight:320.41Miridesap
CAS:Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.Formula:C16H24N2O6Purity:≥95%Color and Shape:SolidMolecular weight:340.37TAE-1
CAS:TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
Formula:C39H51I3N6O9Purity:94.58%Color and Shape:SolidMolecular weight:1128.57Amyloid β-Protein 10-20 acetate
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research ofFormula:C73H103N17O18Purity:97.23%Color and Shape:SolidMolecular weight:1506.65ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Formula:C12H12N2OPurity:99.52% - 99.86%Color and Shape:SolidMolecular weight:200.24Ref: TM-T7490
1mg34.00€5mg74.00€1mL*10mM (DMSO)82.00€10mg113.00€25mg222.00€50mg358.00€100mg530.00€500mg1,153.00€Colivelin
CAS:Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).Formula:C119H206N32O35Purity:96.56%Color and Shape:SolidMolecular weight:2645.1Cromoglicic acid
CAS:Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
Formula:C23H16O11Purity:99.55% - >99.99%Color and Shape:Colorless Crystals From Ethanol + Ether Physical Description Solid (Ntp 1992)Molecular weight:468.37LPYFD-NH2 acetate
LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).Formula:C35H48N6O10Purity:96.51%Color and Shape:SolidMolecular weight:712.79Ref: TM-T22932L
1mg66.00€5mg130.00€10mg187.00€1mL*10mM (DMSO)188.00€25mg309.00€50mg439.00€100mg590.00€200mg793.00€RO4929097
CAS:RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).Formula:C22H20F5N3O3Purity:98.5% - 99.51%Color and Shape:SolidMolecular weight:469.41,1'-Methylenedi-2-naphthol
CAS:1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).Formula:C21H16O2Purity:98.91%Color and Shape:Light Pink To Light Brown Crystalline PowderMolecular weight:300.35RAGE antagonist peptide acetate
RAGE antagonist peptide acetate blocks RAGE-ligands like HMGB-1, has anti-tumor, and anti-inflammatory effects.Formula:C59H105N13O19SPurity:97.17%Color and Shape:SolidMolecular weight:1332.61β-Amyloid 15-21 acetate
β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Formula:C45H69N9O11Purity:99.62%Color and Shape:SolidMolecular weight:912.1MK-0752
CAS:MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).Formula:C21H21ClF2O4SPurity:98% - 99.55%Color and Shape:SolidMolecular weight:442.9CRANAD 2
CAS:CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.Formula:C23H25BF2N2O2Purity:99.44%Color and Shape:Dark Blue To Black PowderMolecular weight:410.27β-Amyloid (31-35)
CAS:β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.Formula:C25H47N5O6SPurity:>99.99%Color and Shape:SolidMolecular weight:545.74EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Formula:C18H18ClMnN2O4Purity:98.39%Color and Shape:SolidMolecular weight:416.74Anle138b
CAS:Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's diseaseFormula:C16H11BrN2O2Purity:98.88% - 99.82%Color and Shape:SolidMolecular weight:343.17Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Formula:C19H27N3O4Purity:97.1% - 99.9%Color and Shape:SolidMolecular weight:361.44PiB
CAS:PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.Formula:C14H12N2OSPurity:97.02%Color and Shape:SolidMolecular weight:256.32Ref: TM-T21000
2mg33.00€5mg48.00€1mL*10mM (DMSO)49.00€10mg62.00€25mg103.00€50mg155.00€100mg224.00€200mg331.00€Solanezumab
CAS:Solanezumab (LY 2062430) is a monoclonal antibody that binds preferentially to soluble amyloid and promotes its clearance from the brain.Purity:96.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 96.3% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.07 kDaγ-Secretase modulator 13
CAS:γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.Formula:C22H23FN6SPurity:99.79%Color and Shape:SolidMolecular weight:422.524-Hydroxyindole
CAS:4-Hydroxyindole: aromatic, antioxidant, used in cancer treatment and preventing neurodegenerative diseases.Formula:C8H7NOPurity:97.05% - 98.13%Color and Shape:Off-White Cyrstalline SolidMolecular weight:133.15Bapineuzumab
CAS:Bapineuzumab (AAB-001) is a humanised monoclonal antibody targeting amyloid-beta (Aβ), soluble and oligomeric forms of amyloid β, Alzheimer's disease (AD).Purity:95%Color and Shape:LiquidMolecular weight:145.86 kDaRemternetug
CAS:Remternetug (LY3372993) is a humanised monoclonal antibody targeting N3pG-Aβ, recognising pyroglutamated Aβ within amyloid plaques, Alzheimer's disease.Purity:95% - 97.6% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.87 kDaDezamizumab
CAS:Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Purity:95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.82 kDaHomotaurine-d6
CAS:Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.Formula:C3D6H3NO3SColor and Shape:SolidMolecular weight:145.214-(6-Bromo-2-benzothiazolyl)benzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.Formula:C13H9BrN2SPurity:98%Color and Shape:SolidMolecular weight:305.19Aftin-5
CAS:Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Formula:C19H26N6OColor and Shape:SolidMolecular weight:354.454-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Formula:C14H11BrN2SPurity:98%Color and Shape:SolidMolecular weight:319.22Nicardipine pyridine metabolite II
CAS:Nicardipine pyridine metabolite II is a biaoctive chemical.Formula:C26H27N3O6Color and Shape:SolidMolecular weight:477.51Eprodisate
CAS:Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Formula:C3H8O6S2Color and Shape:SolidMolecular weight:204.22Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFormula:C22H30N6OColor and Shape:SolidMolecular weight:394.51BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Formula:C28H20F4N6O3Color and Shape:SolidMolecular weight:564.49Caprospinol
CAS:Caprospinol inhibits β-Amyloid (Aβ) protein neurotoxicity.Formula:C33H52O4Purity:98%Color and Shape:SolidMolecular weight:512.76ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Formula:C20H14F5N3O2SColor and Shape:SolidMolecular weight:455.4AZ4800
CAS:AZD4800 is a gamma secretase modulators.Formula:C24H29N5O3Color and Shape:SolidMolecular weight:435.52q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Formula:C21H14O6S4Color and Shape:SolidMolecular weight:490.59BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Formula:C14H12N2SColor and Shape:SolidMolecular weight:240.32Neuroinflammatory-IN-2
CAS:Neuroinflammatory-IN-2: anti-neuroinflammatory, inhibits MAO-B (IC50: 10.30µM), 96.33% Aβ1-42 aggregation reduction, neuroprotective in PC-12 cells.Formula:C25H27FN2O3Color and Shape:SolidMolecular weight:422.49γ-Secretase modulator 12
CAS:γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM.Formula:C25H23N3O2Color and Shape:SolidMolecular weight:397.47JNJ-40418677
CAS:JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.Formula:C26H22F6O2Purity:98%Color and Shape:SolidMolecular weight:480.44Aβ Fibrillization modulator 1
CAS:Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.Formula:C17H12N4O3SSeColor and Shape:SolidMolecular weight:431.33Glutaminyl Cyclase Inhibitor 2
CAS:Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).Formula:C19H20FN3Purity:98%Color and Shape:SolidMolecular weight:309.38SV5
CAS:SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.Formula:C21H30N2O4S2Color and Shape:SolidMolecular weight:438.6KMS88009
CAS:KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.Formula:C19H19NO2Color and Shape:SolidMolecular weight:293.36BACE1/2-IN-1
CAS:BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.Formula:C21H31N5OSColor and Shape:SolidMolecular weight:401.57Chrysamine G
CAS:Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.Formula:C26H16N4Na2O6Color and Shape:SolidMolecular weight:526.416CGP52411
CAS:CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM).Formula:C20H15N3O2Purity:99.78%Color and Shape:SolidMolecular weight:329.35TML-6
CAS:TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.Formula:C30H37NO7Purity:99.71%Color and Shape:SolidMolecular weight:523.62Ref: TM-T37148
1mg94.00€5mg222.00€1mL*10mM (DMSO)256.00€10mg356.00€25mg708.00€50mg1,063.00€100mg1,674.00€K 01-162
CAS:K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.Formula:C15H14BrNColor and Shape:SolidMolecular weight:288.18BChE-IN-8
CAS:BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.Formula:C18H12BrN7O2Color and Shape:SolidMolecular weight:438.24RS-0466
CAS:RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.Formula:C17H17N5O2Purity:98%Color and Shape:SolidMolecular weight:323.35YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFormula:C26H16Br2ClN3Color and Shape:SolidMolecular weight:565.69Antioxidant agent-2
CAS:Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.Formula:C23H26N2O7Color and Shape:SolidMolecular weight:442.46SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Formula:C18H18N4O2Purity:98%Color and Shape:SolidMolecular weight:322.36LC kinetic stabilizer-2
CAS:LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.Formula:C28H31N3O3Color and Shape:SolidMolecular weight:457.56Astrophloxine
CAS:Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue andFormula:C27H33IN2Purity:99.89%Color and Shape:SolidMolecular weight:512.47OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Formula:C32H46N4O2Color and Shape:SolidMolecular weight:518.73THK-523
CAS:THK-523 selectively binds to tau in Alzheimer's, potent in vitro/vivo. 18F-THK523 excels in tau imaging.Formula:C17H15FN2OColor and Shape:SolidMolecular weight:282.31AY1511
CAS:AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].Formula:C17H14O6Color and Shape:SolidMolecular weight:314.29TC-E 5006
CAS:γ-secretase modulatorFormula:C29H29F4NO2Purity:98%Color and Shape:SolidMolecular weight:499.54RU-505
CAS:RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.Formula:C28H32FN5OPurity:98%Color and Shape:SolidMolecular weight:473.58MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.Formula:C18H24N2O2Purity:99.93%Color and Shape:SolidMolecular weight:300.4Ref: TM-T60671
2mg39.00€5mg58.00€1mL*10mM (DMSO)66.00€10mg93.00€25mg167.00€50mg260.00€100mg378.00€200mg552.00€MK-3328
CAS:MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.Formula:C14H9FN4OPurity:99.77% - >99.99%Color and Shape:SolidMolecular weight:268.25Ref: TM-T16094
1mg315.00€5mg745.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Formula:C26H27NO6Purity:98.99%Color and Shape:SolidMolecular weight:449.5Ref: TM-T31773
1mg73.00€2mg98.00€5mg165.00€10mg295.00€25mg532.00€50mg800.00€100mg954.00€200mg1,288.00€Aβ-IN-1
CAS:Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C35H49NPurity:99.1%Color and Shape:SoildMolecular weight:483.77Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Formula:C25H48N6O8S2Purity:99.72%Color and Shape:SolidMolecular weight:624.81Glutaminyl Cyclase Inhibitor 1
CAS:Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.Formula:C21H24FN3O2Purity:99.81%Color and Shape:SolidMolecular weight:369.43Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFormula:C28H27NO3Purity:99.21%Color and Shape:SolidMolecular weight:425.52Ref: TM-T29856
1mg54.00€5mg114.00€1mL*10mM (DMSO)126.00€10mg178.00€25mg409.00€50mg620.00€100mg982.00€200mg1,314.00€BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Formula:C22H23FN6Purity:99.63%Color and Shape:SolidMolecular weight:390.46amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFormula:C30H44N2O14Purity:99.76%Color and Shape:SolidMolecular weight:656.68PPI-1019
CAS:PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).Formula:C36H54N6O5Purity:95.16% - 98.16%Color and Shape:SolidMolecular weight:650.85rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Formula:C18H21FN4O2Purity:99.44%Color and Shape:SolidMolecular weight:344.38TRV-1387
CAS:TRV-1387, a benzofurazan derivative, inhibits the aggregation of tau and amyloid-β [1].Formula:C23H25F3N4O2Color and Shape:SolidMolecular weight:446.47PQM130
CAS:PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.Formula:C23H27NO4Purity:98.73%Color and Shape:SolidMolecular weight:381.46QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Formula:C29H25N4NaO3S2Color and Shape:SolidMolecular weight:564.65ELND007
CAS:ELND007 is a Gamma secretase inhibitor.Formula:C19H14F4N4O2SColor and Shape:SolidMolecular weight:438.4QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Formula:C19H13NO3Color and Shape:SolidMolecular weight:303.31
