Beta Amyloid
Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.
Found 231 products of "Beta Amyloid"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Trontinemab
CAS:Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).Purity:96.77% - 99%Color and Shape:LiquidMolecular weight:194.25 kDaBSB
CAS:BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.Formula:C24H17BrO6Purity:95.53%Color and Shape:SolidMolecular weight:481.29δ-secretase inhibitor 11
CAS:δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.Formula:C10H12N4O2Purity:99.84%Color and Shape:SolidMolecular weight:220.23C18 L-erythro Ceramide (d18:1/18:0)
CAS:C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.Formula:C36H71NO3Color and Shape:SolidMolecular weight:565.95TH-237A
CAS:TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.Formula:C18H17F2NO3Purity:98%Color and Shape:SolidMolecular weight:333.335AZD4694
CAS:Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.Formula:C14H11FN2O2Color and Shape:SolidMolecular weight:258.25(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Formula:C27H27FN2O4Purity:98.27%Color and Shape:SolidMolecular weight:462.51Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Formula:C6H10CuN6S2Purity:99.21%Color and Shape:SolidMolecular weight:293.86Ref: TM-T40792
1mg37.00€5mg77.00€1mL*10mM (DMSO)82.00€10mg119.00€25mg263.00€50mg447.00€100mg749.00€200mg1,017.00€Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Formula:C9H8ClF6NO3S2Color and Shape:SolidMolecular weight:391.74Simufilam hydrochloride
CAS:Simufilam is an oral, low-toxicity FLNA activator for Alzheimer's research, fixing FLNA structure and reducing pathology.Formula:C15H22ClN3OColor and Shape:SolidMolecular weight:295.81Edonerpic maleate
CAS:Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).Formula:C20H25NO6SPurity:98.24%Color and Shape:SolidMolecular weight:407.48Semax acetate(80714-61-0 free base)
CAS:Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.Formula:C39H55N9O12SPurity:99.46%Color and Shape:SolidMolecular weight:873.98Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Formula:C6H7NO2SPurity:99.42% - 99.99%Color and Shape:White Crystalline PowderMolecular weight:157.19JLK6
CAS:JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signallingFormula:C10H8ClNO3Purity:96.50%Color and Shape:SolidMolecular weight:225.63Ref: TM-T21890
1mg84.00€5mg152.00€1mL*10mM (DMSO)160.00€10mg212.00€25mg354.00€50mg504.00€100mg685.00€200mg888.00€β-amyloid 1-11 acetate(190436-05-6 free base)
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Formula:C58H80N16O24Purity:>99.99%Color and Shape:SolidMolecular weight:1385.37Aftin-4
CAS:Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.Formula:C20H28N6OPurity:98.51%Color and Shape:SolidMolecular weight:368.48GSNKGAIIGLM(131602-53-4(free base))
GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide.Formula:C49H83F6N13O18SPurity:>99.99%Color and Shape:SolidMolecular weight:1288.32Ref: TM-T7680
1mg84.00€2mg133.00€5mg197.00€10mg314.00€1mL*10mM (DMSO)479.00€25mg530.00€50mg757.00€100mg1,044.00€Azeliragon HCl
CAS:Azeliragon: potent oral RAGE inhibitor, blocks Alzheimer's-linked amyloid brain entry.Formula:C32H40Cl3N3O2Color and Shape:SolidMolecular weight:605.04Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Formula:C8H10NO6PPurity:97.52%Color and Shape:SolidMolecular weight:247.14Frentizole
CAS:Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interactionFormula:C15H13N3O2SPurity:99.82%Color and Shape:SolidMolecular weight:299.35PE859
CAS:PE859 is a potent inhibitor of both tau and Aβ aggregation.Formula:C28H24N4O2Purity:98.8% - 99.09%Color and Shape:SolidMolecular weight:448.52Dihydroergocristine mesylate
CAS:DHEC mesylate is a vasodilator and α-adrenergic antagonist used for vascular dementia and as a geroprotector.Formula:C36H45N5O8SPurity:98.9% - 99.79%Color and Shape:SolidMolecular weight:707.84PBD-150
CAS:PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)Formula:C15H20N4O2SPurity:99.68%Color and Shape:SolidMolecular weight:320.41Miridesap
CAS:Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.Formula:C16H24N2O6Purity:≥95%Color and Shape:SolidMolecular weight:340.37TAE-1
CAS:TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
Formula:C39H51I3N6O9Purity:94.58%Color and Shape:SolidMolecular weight:1128.57Amyloid β-Protein 10-20 acetate
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research ofFormula:C73H103N17O18Purity:97.23%Color and Shape:SolidMolecular weight:1506.65ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Formula:C12H12N2OPurity:99.52% - 99.86%Color and Shape:SolidMolecular weight:200.24Ref: TM-T7490
1mg34.00€5mg74.00€1mL*10mM (DMSO)82.00€10mg113.00€25mg222.00€50mg358.00€100mg530.00€500mg1,153.00€Colivelin
CAS:Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).Formula:C119H206N32O35Purity:96.56%Color and Shape:SolidMolecular weight:2645.1Cromoglicic acid
CAS:Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
Formula:C23H16O11Purity:99.55% - >99.99%Color and Shape:Colorless Crystals From Ethanol + Ether Physical Description Solid (Ntp 1992)Molecular weight:468.37LPYFD-NH2 acetate
LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).Formula:C35H48N6O10Purity:96.51%Color and Shape:SolidMolecular weight:712.79Ref: TM-T22932L
1mg66.00€5mg130.00€10mg187.00€1mL*10mM (DMSO)188.00€25mg309.00€50mg439.00€100mg590.00€200mg793.00€RO4929097
CAS:RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).Formula:C22H20F5N3O3Purity:98.5% - 99.51%Color and Shape:SolidMolecular weight:469.41,1'-Methylenedi-2-naphthol
CAS:1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).Formula:C21H16O2Purity:98.91%Color and Shape:Light Pink To Light Brown Crystalline PowderMolecular weight:300.35RAGE antagonist peptide acetate
RAGE antagonist peptide acetate blocks RAGE-ligands like HMGB-1, has anti-tumor, and anti-inflammatory effects.Formula:C59H105N13O19SPurity:97.17%Color and Shape:SolidMolecular weight:1332.61β-Amyloid 15-21 acetate
β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Formula:C45H69N9O11Purity:99.62%Color and Shape:SolidMolecular weight:912.1MK-0752
CAS:MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).Formula:C21H21ClF2O4SPurity:98% - 99.55%Color and Shape:SolidMolecular weight:442.9CRANAD 2
CAS:CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.Formula:C23H25BF2N2O2Purity:99.44%Color and Shape:Dark Blue To Black PowderMolecular weight:410.27β-Amyloid (31-35)
CAS:β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.Formula:C25H47N5O6SPurity:>99.99%Color and Shape:SolidMolecular weight:545.74EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Formula:C18H18ClMnN2O4Purity:98.39%Color and Shape:SolidMolecular weight:416.74Anle138b
CAS:Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's diseaseFormula:C16H11BrN2O2Purity:98.88% - 99.82%Color and Shape:SolidMolecular weight:343.17Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Formula:C19H27N3O4Purity:97.1% - 99.9%Color and Shape:SolidMolecular weight:361.44PiB
CAS:PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.Formula:C14H12N2OSPurity:97.02%Color and Shape:SolidMolecular weight:256.32Ref: TM-T21000
2mg33.00€5mg48.00€1mL*10mM (DMSO)49.00€10mg62.00€25mg103.00€50mg155.00€100mg224.00€200mg331.00€Solanezumab
CAS:Solanezumab (LY 2062430) is a monoclonal antibody that binds preferentially to soluble amyloid and promotes its clearance from the brain.Purity:96.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 96.3% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.07 kDaγ-Secretase modulator 13
CAS:γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.Formula:C22H23FN6SPurity:99.79%Color and Shape:SolidMolecular weight:422.524-Hydroxyindole
CAS:4-Hydroxyindole: aromatic, antioxidant, used in cancer treatment and preventing neurodegenerative diseases.Formula:C8H7NOPurity:97.05% - 98.13%Color and Shape:Off-White Cyrstalline SolidMolecular weight:133.15Bapineuzumab
CAS:Bapineuzumab (AAB-001) is a humanised monoclonal antibody targeting amyloid-beta (Aβ), soluble and oligomeric forms of amyloid β, Alzheimer's disease (AD).Purity:95%Color and Shape:LiquidMolecular weight:145.86 kDaRemternetug
CAS:Remternetug (LY3372993) is a humanised monoclonal antibody targeting N3pG-Aβ, recognising pyroglutamated Aβ within amyloid plaques, Alzheimer's disease.Purity:95% - 97.6% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.87 kDaDezamizumab
CAS:Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Purity:95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.82 kDaHomotaurine-d6
CAS:Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.Formula:C3D6H3NO3SColor and Shape:SolidMolecular weight:145.214-(6-Bromo-2-benzothiazolyl)benzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.Formula:C13H9BrN2SPurity:98%Color and Shape:SolidMolecular weight:305.19Aftin-5
CAS:Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Formula:C19H26N6OColor and Shape:SolidMolecular weight:354.45
