Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
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SC-236
CAS:170569-86-5
SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 …
Formula:
C16H11ClF3N3O2S
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
401.79
Ref: TM-T8505
| 1mg | 35.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 98.00 € | ||
| 25mg | 195.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 515.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Isoorientin
CAS:4261-42-1
Isoorientin (Homoorientin) has antioxidant activity.
Formula:
C21H20O11
Purity:
98.84% - 99.48%
Color and Shape:
Solid
Molecular weight:
448.38
Ref: TM-T6S0722
| 1mg | 38.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 550.00 € | ||
| 500mg | 1,157.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
(-)-Epicatechin
CAS:490-46-0
(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by …
Formula:
C15H14O6
Purity:
98.55% - ≥95%
Color and Shape:
Solid
Molecular weight:
290.27
Ref: TM-T2856
| 10mg | 57.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 93.00 € | ||
| 100mg | 116.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Choline Fenofibrate
CAS:856676-23-8
Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and …
Formula:
C22H28ClNO5
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
421.91
Ref: TM-T3941
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 149.00 € | ||
| 100mg | 213.00 € | ||
| 200mg | 316.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Roburic acid
CAS:6812-81-3
Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.
Formula:
C30H48O2
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
440.7
Ref: TM-T3883
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 458.00 € | ||
| 100mg | 640.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
7,3',4'-Tri-O-methylluteolin
CAS:29080-58-8
7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).
Formula:
C18H16O6
Purity:
98% - 98.66%
Color and Shape:
Solid
Molecular weight:
328.32
Ref: TM-TN1291
| 1mg | 96.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 443.00 € | ||
| 50mg | 636.00 € | ||
| 100mg | 881.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Regaloside B
CAS:114420-67-6
Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression …
Formula:
C20H26O11
Purity:
97.34% - 99.4%
Color and Shape:
Solid
Molecular weight:
442.41
Ref: TM-TN2139
| 1mg | 68.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 217.00 € | ||
| 25mg | 360.00 € | ||
| 50mg | 527.00 € | ||
| 100mg | 757.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
NS-398
CAS:123653-11-2
NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.
Formula:
C13H18N2O5S
Purity:
99% - 99.72%
Color and Shape:
Solid
Molecular weight:
314.36
Ref: TM-T3214
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 174.00 € | ||
| 100mg | 270.00 € | ||
| 200mg | 348.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Tolmetin
CAS:26171-23-3
Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.
Formula:
C15H15NO3
Purity:
99.69% - 99.88%
Color and Shape:
Off-White Crystalline Power
Molecular weight:
257.28
Ref: TM-T2550
| 50mg | 38.00 € | ||
| 100mg | 51.00 € | ||
| 200mg | 72.00 € | ||
| 500mg | 111.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
α-Spinasterol
CAS:481-18-5
α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and …
Formula:
C29H48O
Purity:
99.58% - 99.58%
Color and Shape:
Solid
Molecular weight:
412.69
Ref: TM-TN1377
| 1mg | 46.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 261.00 € | ||
| 50mg | 375.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Cis-5-Dodecenoic Acid
CAS:2430-94-6
Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone …
Formula:
C12H22O2
Purity:
98% - 99.37%
Color and Shape:
Solid
Molecular weight:
198.3
Ref: TM-T8240
| 10mg | 44.00 € | ||
| 25mg | 64.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Avicularin
CAS:572-30-5
Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in …
Formula:
C20H18O11
Purity:
97.02% - 99.43%
Color and Shape:
White Powder
Molecular weight:
434.35
Ref: TM-T6S0117
| 1mg | 56.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 272.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Hamaudol
CAS:735-46-6
Hamaudol, from Saposhnikovia divaricata, has pain-relief and anti-inflammatory effects, inhibits COX-1/COX-2 (0.30/0.57 mM).
Formula:
C15H16O5
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
276.28
Ref: TM-TN1723
| 1mg | 90.00 € | ||
| 5mg | 221.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Adelmidrol
CAS:1675-66-7
Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.
Formula:
C13H26N2O4
Purity:
100% - 99.35%
Color and Shape:
Solid
Molecular weight:
274.36
Ref: TM-T3954
| 50mg | 46.00 € | ||
| 100mg | 62.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
(-)-Catechin gallate
CAS:130405-40-2
(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.
Formula:
C22H18O10
Purity:
100% - 97.74%
Color and Shape:
Solid
Molecular weight:
442.37
Ref: TM-T3682
| 1mg | 73.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 461.00 € | ||
| 50mg | 579.00 € | ||
| 100mg | 870.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Lumiracoxib
CAS:220991-20-8
Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM …
Formula:
C15H13ClFNO2
Purity:
96.64% - 99.25%
Color and Shape:
Pale Yellow Solid
Molecular weight:
293.72
Ref: TM-T6574
| 10mg | 36.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 75.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
FK 3311
CAS:116686-15-8
FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts …
Formula:
C15H13F2NO4S
Purity:
97.3%
Color and Shape:
Solid
Molecular weight:
341.33
Ref: TM-T7207
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 246.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 535.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Propyphenazone
CAS:479-92-5
Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.
Formula:
C14H18N2O
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
230.31
Ref: TM-T5010
| 1g | 47.00 € | ||
| 5g | 89.00 € | ||
| 10g | 128.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Teriflunomide impurity 3
CAS:1011244-72-6
Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).
Formula:
C14H11F3N2O
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
280.25
Ref: TM-T9042
| 10mg | 50.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 131.00 € | ||
| 100mg | 208.00 € | ||
| 200mg | 296.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Otenaproxesul
CAS:1226895-20-0
Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
Formula:
C21H19NO3S
Purity:
97.98% - 99.23%
Color and Shape:
Solid
Molecular weight:
365.45
Ref: TM-T1867
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 435.00 € | ||
| 500mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
