Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 600 products of "Cyclooxygenase (COX) Inhibitors"
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FK 3311
CAS:FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (Formula:C15H13F2NO4SPurity:97.98%Color and Shape:SolidMolecular weight:341.33Dehydroevodiamine
CAS:Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressantFormula:C19H15N3OPurity:99.54%Color and Shape:SolidMolecular weight:301.34Byakangelicol
CAS:Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.
Formula:C17H16O6Purity:98.78% - 99.55%Color and Shape:SolidMolecular weight:316.31Bromfenac
CAS:Bromfenac, a potent COX inhibitor, targets ocular inflammation with IC50s of 5.56 nM for COX-1 and 7.45 nM for COX-2.Formula:C15H12BrNO3Color and Shape:SolidMolecular weight:334.16Pectolinarigenin
CAS:Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.Formula:C17H14O6Purity:98.67% - 99.88%Color and Shape:SolidMolecular weight:314.29Ref: TM-T6S0413
1mg46.00€5mg89.00€10mg154.00€25mg265.00€50mg409.00€100mg620.00€1mL*10mM (DMSO)110.00€Metyrosine
CAS:Metyrosine: antihypertensive, tyrosine hydroxylase inhibitor, controls COX-2, lowers blood pressure.Formula:C10H13NO3Purity:98.68% - 99.72%Color and Shape:SolidMolecular weight:195.22Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formula:C9H10N2OPurity:97.24%Color and Shape:White Solid Solid CrystallineMolecular weight:162.19Lumiracoxib
CAS:Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
Formula:C15H13ClFNO2Purity:96.64% - 99.77%Color and Shape:Pale Yellow SolidMolecular weight:293.72Tenidap Sodium
CAS:Tenidap Sodium is a COX/5-LOX inhibitor and cytokine-modulating anti-inflammatory agent.Formula:C14H8ClN2NaO3SColor and Shape:SolidMolecular weight:342.72γ-Tocopherol
CAS:(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.Formula:C28H48O2Purity:99.31% - 99.39%Color and Shape:Clear Viscous Pale Yellow Oil Which Oxidises And Darkens On Exposure To Air Or LightMolecular weight:416.68(-)-Catechin gallate
CAS:(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.Formula:C22H18O10Purity:97.74% - >99.99%Color and Shape:SolidMolecular weight:442.37Chlorotrianisene
CAS:Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.Formula:C23H21ClO3Purity:98.88% - 99.03%Color and Shape:Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)Molecular weight:380.86Ref: TM-T2569
1mg54.00€5mg114.00€10mg178.00€25mg313.00€50mg464.00€100mg660.00€200mg888.00€1mL*10mM (DMSO)126.00€Compound Lup-20(29)-en-3-yl acetate
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.Formula:C32H52O2Purity:98%Color and Shape:SolidMolecular weight:468.75N-tert-butyl-α-Phenylnitrone
CAS:N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.Formula:C11H15NOPurity:99.46% - 99.84%Color and Shape:SolidMolecular weight:177.24CAY10404
CAS:CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.Formula:C17H12F3NO3SPurity:99.02%Color and Shape:SolidMolecular weight:367.34RHC 80267
CAS:RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)Formula:C20H34N4O4Purity:99.54%Color and Shape:White SolidMolecular weight:394.51Isofraxidin
CAS:Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.Formula:C11H10O5Purity:99.51% - ≥95%Color and Shape:SolidMolecular weight:222.19Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36Hamaudol
CAS:Hamaudol, from Saposhnikovia divaricata, has pain-relief and anti-inflammatory effects, inhibits COX-1/COX-2 (0.30/0.57 mM).Formula:C15H16O5Purity:99.62% - 99.76%Color and Shape:SolidMolecular weight:276.28Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg55.00€5mg92.00€10mg152.00€25mg268.00€50mg395.00€100mg583.00€200mg832.00€1mL*10mM (DMSO)105.00€
