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CaMK

CaMK

Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are compounds that block the activity of CaMK, a kinase involved in regulating various cellular processes, including synaptic plasticity, memory formation, and gene expression in the nervous system. CaMK plays a critical role in translating calcium signals into cellular responses, and its dysregulation is associated with neurological disorders. Inhibitors of CaMK are valuable tools for studying synaptic signaling, learning, and memory. At CymitQuimica, we offer CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.

Found 68 products of "CaMK"

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  • KN-62
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    KN-62

    CAS:
    <p>KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.</p>
    Formula:C38H35N5O6S2
    Purity:99.80% - >99.99%
    Color and Shape:White Solid
    Molecular weight:721.84

    Ref: TM-T2694

  • CaMKP Inhibitor
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    CaMKP Inhibitor

    CAS:
    <p>CaMKP Inhibitor can inhibit CaMKP.</p>
    Formula:C10H8NNaO7S2
    Purity:96.55% - 99.98%
    Color and Shape:Solid
    Molecular weight:341.28

    Ref: TM-T2159

  • IGS-1.76
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    IGS-1.76

    CAS:
    <p>IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.</p>
    Formula:C22H18N2OS
    Purity:98.18% - 98.56%
    Color and Shape:Solid
    Molecular weight:358.46

    Ref: TM-T8784

  • GSK3i XIII
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    GSK3i XIII

    CAS:
    <p>GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.</p>
    Formula:C18H19N5
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:305.38

    Ref: TM-T24111

  • CALP2 acetate(261969-04-4 free base)
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    CALP2 acetate(261969-04-4 free base)

    <p>CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM.</p>
    Formula:C68H104N14O13S
    Purity:97.43%
    Color and Shape:Solid
    Molecular weight:1357.7

    Ref: TM-TP1909L1

  • L-6355
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    L-6355

    CAS:
    <p>L-6355 is an agent of bioactive chemicals.</p>
    Formula:C25H30INO3
    Color and Shape:Solid
    Molecular weight:519.42

    Ref: TM-T20141

  • CK59
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    CK59

    CAS:
    <p>CK59 inhibits CaMKII and several voltage-gated calcium channels, with an IC50 of ~50 μM.</p>
    Formula:C21H37N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:435.56

    Ref: TM-T27032

  • W-5 hydrochloride
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    W-5 hydrochloride

    CAS:
    <p>W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist.</p>
    Formula:C16H23ClN2O2S
    Purity:99.35%
    Color and Shape:Off-White Crystalline Solid
    Molecular weight:342.88

    Ref: TM-T23523

  • Bisindolylmaleimide VII
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    Bisindolylmaleimide VII

    CAS:
    <p>Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.</p>
    Formula:C27H27N5O2
    Color and Shape:Solid
    Molecular weight:453.54

    Ref: TM-T70832

  • TIM-063
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    TIM-063

    CAS:
    <p>TIM-063: ATP-competitive CaMKKα/β inhibitor, cell-permeable, Ki: 0.35/0.2 μM, IC50: 0.63/0.96 μM.</p>
    Formula:C18H9N3O4
    Color and Shape:Solid
    Molecular weight:331.28

    Ref: TM-T73445

  • CBP501
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    CBP501

    CAS:
    <p>CBP501 peptide inhibits kinases like MAPKAP-K2/C-Tak1/CHK1, preventing Cdc25C function and blocking the entry into mitosis.</p>
    Formula:C86H122F5N29O17
    Color and Shape:Solid
    Molecular weight:1929.06

    Ref: TM-T69091

  • Ph-HTBA
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    Ph-HTBA

    CAS:
    <p>Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.</p>
    Formula:C19H18O3
    Color and Shape:Solid
    Molecular weight:294.34

    Ref: TM-T73455

  • A-7 hydrochloride
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    A-7 hydrochloride

    CAS:
    <p>A-7 hydrochloride is a calmodulin antagonist and causes alterations in the subpopulation of CD44+CD24- in MDA-MB-231 cells.</p>
    Formula:C20H30Cl2N2O2S
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:433.44

    Ref: TM-T22538

  • RU 45144
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    RU 45144

    CAS:
    <p>RU 45144 is an estradiol derivative with antiestrogenic activity.</p>
    Formula:C28H37NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:435.6

    Ref: TM-T26154

  • HOCPCA
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    HOCPCA

    CAS:
    <p>HOCPCA: potent, selective GHB site ligand; 27x higher affinity than GHB; crosses blood-brain barrier.</p>
    Formula:C6H8O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:128.13

    Ref: TM-T24146

  • W-13 hydrochloride
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    W-13 hydrochloride

    CAS:
    <p>W-13 hydrochloride (W-13 HCl) is a calmodulin antagonist.</p>
    Formula:C14H18Cl2N2O2S
    Purity:98.51%
    Color and Shape:White Powder
    Molecular weight:349.28

    Ref: TM-T23522

  • Prenylamine lactate
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    Prenylamine lactate

    CAS:
    <p>Prenylamine lactate, an ex-angina drug, depletes heart catecholamines and blocks calcium channels.</p>
    Formula:C27H33NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:419.56

    Ref: TM-T24659

  • Zaldaride maleate
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    Zaldaride maleate

    CAS:
    <p>Zaldaride maleate blocks Ca2+, Na+, K+ currents, and nAChR; inhibits CaM cAMP PDE (IC50: 3.3 nM) and estrogen signaling.</p>
    Formula:C30H32N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:544.6

    Ref: TM-T17282

  • TX-1123
    Targetmol
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    TX-1123

    CAS:
    <p>TX-1123: PTK/COX inhibitor, Src/eEF2-K/PKA/EGFR-K/PKC targeted, IC50 of 1.16μM(COX2), 15.7μM(COX1), low mitochondrial toxicity.</p>
    Formula:C20H24O3
    Color and Shape:Solid
    Molecular weight:312.4

    Ref: TM-T70431

  • CV-159
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    CV-159

    CAS:
    <p>CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action.</p>
    Formula:C31H34N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:574.62

    Ref: TM-T15021