CaMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are compounds that block the activity of CaMK, a kinase involved in regulating various cellular processes, including synaptic plasticity, memory formation, and gene expression in the nervous system. CaMK plays a critical role in translating calcium signals into cellular responses, and its dysregulation is associated with neurological disorders. Inhibitors of CaMK are valuable tools for studying synaptic signaling, learning, and memory. At CymitQuimica, we offer CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Found 66 products for "CaMK".
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IGS-1.76
CAS:IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.Formula:C22H18N2OSPurity:98.18% - 98.56%Color and Shape:SolidMolecular weight:358.46L-6355
CAS:L-6355 is an agent of bioactive chemicals.Formula:C25H30INO3Color and Shape:SolidMolecular weight:519.42W-5 hydrochloride
CAS:W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist.Formula:C16H23ClN2O2SPurity:99.35%Color and Shape:SolidMolecular weight:342.88A-7 hydrochloride
CAS:A-7 hydrochloride is a calmodulin antagonist and causes alterations in the subpopulation of CD44+CD24- in MDA-MB-231 cells.Formula:C20H30Cl2N2O2SPurity:99.38%Color and Shape:SolidMolecular weight:433.44Prenylamine lactate
CAS:Prenylamine lactate, an ex-angina drug, depletes heart catecholamines and blocks calcium channels.Formula:C27H33NO3Purity:98%Color and Shape:SolidMolecular weight:419.56Zaldaride maleate
CAS:Zaldaride maleate blocks Ca2+, Na+, K+ currents, and nAChR; inhibits CaM cAMP PDE (IC50: 3.3 nM) and estrogen signaling.Formula:C30H32N4O6Purity:98%Color and Shape:SolidMolecular weight:544.6TX-1123
CAS:TX-1123: PTK/COX inhibitor, Src/eEF2-K/PKA/EGFR-K/PKC targeted, IC50 of 1.16μM(COX2), 15.7μM(COX1), low mitochondrial toxicity.Formula:C20H24O3Color and Shape:SolidMolecular weight:312.4CV-159
CAS:CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action.Formula:C31H34N4O7Purity:98%Color and Shape:SolidMolecular weight:574.62CK59
CAS:CK59 inhibits CaMKII and several voltage-gated calcium channels, with an IC50 of ~50 μM.Formula:C21H37N7O3Purity:98%Color and Shape:SolidMolecular weight:435.56Bisindolylmaleimide VII
CAS:Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.Formula:C27H27N5O2Color and Shape:SolidMolecular weight:453.54TIM-063
CAS:TIM-063: ATP-competitive CaMKKα/β inhibitor, cell-permeable, Ki: 0.35/0.2 μM, IC50: 0.63/0.96 μM.Formula:C18H9N3O4Color and Shape:SolidMolecular weight:331.28CBP501
CAS:CBP501 peptide inhibits kinases like MAPKAP-K2/C-Tak1/CHK1, preventing Cdc25C function and blocking the entry into mitosis.Formula:C86H122F5N29O17Color and Shape:SolidMolecular weight:1929.06Ph-HTBA
CAS:Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.Formula:C19H18O3Color and Shape:SolidMolecular weight:294.34RU 45144
CAS:RU 45144 is an estradiol derivative with antiestrogenic activity.Formula:C28H37NO3Purity:98%Color and Shape:SolidMolecular weight:435.6HOCPCA
CAS:HOCPCA: potent, selective GHB site ligand; 27x higher affinity than GHB; crosses blood-brain barrier.Formula:C6H8O3Purity:98%Color and Shape:SolidMolecular weight:128.13W-13 hydrochloride
CAS:W-13 hydrochloride (W-13 HCl) is a calmodulin antagonist.Formula:C14H18Cl2N2O2SPurity:98.51%Color and Shape:SolidMolecular weight:349.28W-9 hydrochloride
CAS:W-9 hydrochloride is a calmodulin antagonist.Formula:C16H22Cl2N2O2SPurity:98.9%Color and Shape:White SolidMolecular weight:377.33Ref: TM-T23525
500mgTo inquire1mg34.00€2mg42.00€5mg60.00€1mL*10mM (DMSO)66.00€10mg90.00€25mg173.00€50mg269.00€100mg389.00€Calmidazolium chloride
CAS:Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.Formula:C31H23Cl7N2OPurity:98.53%Color and Shape:SolidMolecular weight:687.7Ref: TM-T10667
5mg59.00€1mL*10mM (DMSO)90.00€10mg93.00€25mg138.00€50mg203.00€100mg304.00€200mg442.00€Zaldaride (free base)
CAS:Zaldaride (free base) is a calmodulin antagonist.Formula:C26H28N4O2Color and Shape:SolidMolecular weight:428.53CaMKK2-IN-1
CAS:CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.Formula:C22H22N2O3Color and Shape:SolidMolecular weight:362.42
