CymitQuimica logo
CaMK

CaMK

Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are compounds that block the activity of CaMK, a kinase involved in regulating various cellular processes, including synaptic plasticity, memory formation, and gene expression in the nervous system. CaMK plays a critical role in translating calcium signals into cellular responses, and its dysregulation is associated with neurological disorders. Inhibitors of CaMK are valuable tools for studying synaptic signaling, learning, and memory. At CymitQuimica, we offer CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.

Found 68 products of "CaMK"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • W-9 hydrochloride
    Targetmol
    + Info

    W-9 hydrochloride

    CAS:
    <p>W-9 hydrochloride is a calmodulin antagonist.</p>
    Formula:C16H22Cl2N2O2S
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:377.33

    Ref: TM-T23525

  • Calmidazolium chloride
    Targetmol
    + Info

    Calmidazolium chloride

    CAS:
    <p>Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.</p>
    Formula:C31H23Cl7N2O
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:687.7

    Ref: TM-T10667

  • FO-4-15
    Targetmol
    + Info

    FO-4-15

    CAS:
    <p>FO-4-15 is an activator of mGluR1/CaMKIIα. It exhibits protective effects against H2O2 in human neuroblastoma (SH-SY5Y) cells. In mice with Alzheimer's disease, FO-4-15 enhances cognitive function by activating the mGluR1/CaMKIIα pathway, reducing Aβ accumulation, Tau hyperphosphorylation, and synaptic damage.</p>
    Formula:C18H20N4O4S
    Color and Shape:Solid
    Molecular weight:388.44

    Ref: TM-T200203

  • BRD0418
    Targetmol
    + Info

    BRD0418

    CAS:
    <p>BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.</p>
    Formula:C29H32N2O5
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:488.57

    Ref: TM-T30577

  • CymitQuimica logo
    Targetmol
    + Info

    CaMKK2-IN-1

    CAS:
    <p>CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.</p>
    Formula:C22H22N2O3
    Molecular weight:362.42

    Ref: TM-T208827

  • PTCA
    Targetmol
    + Info

    PTCA

    CAS:
    <p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>
    Formula:C10H5Cl2NO2S
    Color and Shape:Solid
    Molecular weight:274.123

    Ref: TM-T204835

  • CymitQuimica logo
    Targetmol
    + Info

    CaMKIIα-IN-1

    <p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>
    Formula:C14H11ClO4
    Color and Shape:Solid
    Molecular weight:278.69

    Ref: TM-T60515

  • Calmodulin antagonist-1
    Targetmol
    + Info

    Calmodulin antagonist-1

    CAS:
    <p>Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.</p>
    Formula:C14H18Cl2N2O2S
    Color and Shape:Solid
    Molecular weight:349.27

    Ref: TM-T40895

    ne
    Discontinued
    Discontinued product