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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 574 products of "AChR"

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  • Cevimeline hydrochloride hemihydrate

    CAS:
    <p>Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.</p>
    Formula:C20H38Cl2N2O3S2
    Purity:97.00%
    Color and Shape:Solid
    Molecular weight:489.55
  • AC1-IN-1

    CAS:
    <p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>
    Formula:C18H18FN5O2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:355.37
  • ANQ-9040

    CAS:
    <p>ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.</p>
    Formula:C36H58N2O5S
    Color and Shape:Solid
    Molecular weight:630.92
  • Biperiden Hydrochloride

    CAS:
    <p>Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.</p>
    Formula:C21H30ClNO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:347.92
  • nAChR agonist 2

    CAS:
    <p>Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,</p>
    Formula:C11H16N2
    Color and Shape:Solid
    Molecular weight:176.263
  • Emraclidine

    CAS:
    <p>Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.</p>
    Formula:C20H21F3N4O
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:390.4
  • TIP 39, Tuberoinfundibular Neuropeptide

    CAS:
    <p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>
    Formula:C202H325N61O54S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4504.2
  • Lupanine hydrochloride

    CAS:
    <p>Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.</p>
    Formula:C15H25ClN2O
    Color and Shape:Solid
    Molecular weight:284.83
  • Pozanicline hydrochloride


    <p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>
    Formula:C11H17ClN2O
    Purity:97.13% - 99.81%
    Color and Shape:Solid
    Molecular weight:228.72
  • PDE4-IN-4

    CAS:
    <p>PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment of</p>
    Formula:C36H37Cl2N3O7S
    Color and Shape:Solid
    Molecular weight:726.67
  • Methylatropine (nitrate)

    CAS:
    <p>Methylatropine: Muscarinic antagonist, &lt;0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.</p>
    Formula:C18H26N2O6
    Color and Shape:Solid
    Molecular weight:366.414
  • nAChR modulator-1

    CAS:
    <p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>
    Formula:C12H8ClN3O2
    Color and Shape:Solid
    Molecular weight:261.66
  • Heliosupine N-oxide


    <p>Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.</p>
    Formula:C20H31NO8
    Color and Shape:Solid
    Molecular weight:413.467
  • Small Cardioactive Peptide B (SCPB)

    CAS:
    <p>SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).</p>
    Formula:C52H80N14O11S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1141.41
  • Epiboxidine

    CAS:
    <p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>
    Formula:C10H14N2O
    Color and Shape:Solid
    Molecular weight:178.23
  • M 8218

    CAS:
    <p>M 8218 is a bioactive chemical.</p>
    Formula:C20H29NO2
    Color and Shape:Solid
    Molecular weight:315.45
  • Desfesoterodine

    CAS:
    <p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>
    Formula:C22H31NO2
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:341.49
  • α-Conotoxin AuIB

    CAS:
    <p>Selective antagonist of α3β4 nicotinic acetylcholine receptors.</p>
    Formula:C65H89N17O21S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1572.76
  • Flupyradifurone

    CAS:
    <p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>
    Formula:C12H11ClF2N2O2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:288.68
  • α-Conotoxin imi

    CAS:
    <p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>
    Formula:C52H78N20O15S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1351.56
  • Tiquizium

    CAS:
    <p>Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.</p>
    Formula:C19H24NS2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:330.53
  • CVN417


    <p>CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.</p>
    Color and Shape:Odour Solid
  • Perindoprilat

    CAS:
    <p>Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.</p>
    Formula:C17H28N2O5
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:340.41
  • Dicloromezotiaz

    CAS:
    <p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>
    Formula:C19H12Cl3N3O2S
    Color and Shape:Solid
    Molecular weight:452.74
  • [D-Trp7,9,10]-Substance P

    CAS:
    <p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>
    Formula:C79H105N21O13S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1588.89
  • SIB 1553A

    CAS:
    <p>SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.</p>
    Formula:C13H19NOS
    Purity:99.79%
    Color and Shape:Soild
    Molecular weight:237.36
  • (+)-Coclaurine hydrochloride

    CAS:
    <p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>
    Formula:C17H20ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:321.8
  • Destomycin A

    CAS:
    <p>Destomycin A, an aminoglycoside antibiotic, exhibits activity against bacterial (Gram-positive and Gram-negative), antifungal, and anthelmintic agents. It inhibits peptide synthesis in Escherichia coli cells and stimulates adenylate cyclase in animal tissues.</p>
    Formula:C20H37N3O13
    Color and Shape:Solid
    Molecular weight:527.52
  • CDD0102 HCl

    CAS:
    <p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>
    Formula:C8H13ClN4O
    Purity:99.7%
    Color and Shape:Soild
    Molecular weight:216.67
  • Mant-GTPγS

    CAS:
    <p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>
    Formula:C18H23N6O14P3S
    Color and Shape:Solid
    Molecular weight:672.39
  • Navafenterol saccharinate

    CAS:
    <p>AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).</p>
    Formula:C45H47N7O9S3
    Color and Shape:Solid
    Molecular weight:926.09
  • Thiothixene

    CAS:
    <p>Thiothixene has a wide range of applications in life science related research.</p>
    Formula:C23H29N3O2S2
    Color and Shape:Solid
    Molecular weight:443.62
  • Fentonium bromide

    CAS:
    <p>Fentonium bromide is a biochemical.</p>
    Formula:C31H34BrNO4
    Color and Shape:Solid
    Molecular weight:564.51
  • (S)-UFR2709 hydrochloride

    CAS:
    <p>(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety &amp; alcohol intake in rats, studies nicotine addiction.</p>
    Formula:C13H18ClNO2
    Purity:98.94%
    Color and Shape:Solid
    Molecular weight:255.74
  • PF-06827443


    <p>PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.</p>
    Formula:C24H24N2O4
    Color and Shape:Solid
    Molecular weight:404.47
  • 5-Hydroxymethyl tolterodine formate

    CAS:
    <p>5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.</p>
    Formula:C23H33NO4
    Color and Shape:Solid
    Molecular weight:387.51
  • (Rac)-5-Carboxy tolterodine

    CAS:
    <p>(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.</p>
    Formula:C22H29NO3
    Color and Shape:Solid
    Molecular weight:355.47
  • RuBi-Nicotine

    CAS:
    <p>Nicotinic receptor agonist</p>
    Formula:C40H44Cl2N8Ru
    Purity:98%
    Color and Shape:Solid
    Molecular weight:808.81
  • (Rac)-5-Hydroxymethyl Tolterodine hydrochloride

    CAS:
    <p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>
    Formula:C22H32ClNO2
    Color and Shape:Solid
    Molecular weight:377.95
  • NNC 11-1607

    CAS:
    <p>NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.</p>
    Formula:C30H32N6O2S2
    Color and Shape:Solid
    Molecular weight:572.74
  • N,N-Dicyclohexylcarbodiimide

    CAS:
    <p>N,N-Dicyclohexylcarbodiimide (Dicyclohexylcarbodiimide) is a cross-linking agent used in the synthesis of active ester-containing reagents.</p>
    Formula:C13H22N2
    Purity:98.28% - 99.73%
    Color and Shape:Solid
    Molecular weight:206.33
  • bPiDDB

    CAS:
    <p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>
    Formula:C24H38Br2N2
    Purity:98.72%
    Color and Shape:Solid
    Molecular weight:514.38
  • TC-2216

    CAS:
    <p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>
    Formula:C12H17N3
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:203.28
  • Irsogladine maleate

    CAS:
    <p>Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C9H7Cl2N5
    Color and Shape:Solid
    Molecular weight:256.09
  • trans-Cevimeline hydrochloride

    CAS:
    <p>AF 102A hydrochloride is a biochemical.</p>
    Formula:C10H18ClNOS
    Color and Shape:Solid
    Molecular weight:235.77
  • Lobeline sulfate

    CAS:
    <p>Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.</p>
    Formula:C22H29NO6S
    Purity:98%
    Color and Shape:White Powder
    Molecular weight:435.54
  • Hydroxybupropion

    CAS:
    <p>Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).</p>
    Formula:C13H18ClNO2
    Purity:99.73%
    Color and Shape:Off-White Solid
    Molecular weight:255.74
  • Oxotremorine

    CAS:
    <p>Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.</p>
    Formula:C12H18N2O
    Color and Shape:Solid
    Molecular weight:206.28
  • Methyllycaconitine citrate

    CAS:
    <p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>
    Formula:C43H58N2O17
    Purity:98.03% - 98.91%
    Color and Shape:Solid
    Molecular weight:874.92
  • G-Protein antagonist peptide

    CAS:
    <p>Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.</p>
    Formula:C57H64N12O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1093.27
  • M4 mAChR agonist-1 

    CAS:
    <p>M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 &gt;10 μM).</p>
    Formula:C14H18N4OS
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:290.38
  • Muscarine

    CAS:
    <p>Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>
    Formula:C9H20NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:174.26
  • M3/PDE4 modulator-1


    <p>M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.</p>
    Formula:C38H41Cl2N3O8S
    Color and Shape:Solid
    Molecular weight:770.72
  • 5-AMAM-2-CP

    CAS:
    <p>5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].</p>
    Formula:C9H11ClN2O
    Color and Shape:Solid
    Molecular weight:198.65
  • (R)-Dinotefuran

    CAS:
    <p>(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.</p>
    Formula:C7H14N4O3
    Color and Shape:Solid
    Molecular weight:202.21
  • Ebiratide TFA


    <p>Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.</p>
    Formula:C48H73N11O10S·xC2HF3O2
    Color and Shape:Solid
    Molecular weight:996.23 (free base)
  • TDI-10229

    CAS:
    <p>TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.</p>
    Formula:C16H16ClN5
    Purity:99.85% - 99.89%
    Color and Shape:Soild
    Molecular weight:313.78
  • BTMPS

    CAS:
    <p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>
    Formula:C28H52N2O4
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:480.72
  • Anabaseine

    CAS:
    <p>Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.</p>
    Formula:C10H12N2
    Color and Shape:Solid
    Molecular weight:160.22
  • N-Ethyl-N-(3-pyridylmethyl)amine

    CAS:
    <p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>
    Formula:C8H12N2
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:136.19
  • Soclenicant

    CAS:
    <p>Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availability</p>
    Formula:C24H26N4O3
    Purity:99.57%
    Color and Shape:Soild
    Molecular weight:418.49
  • Rivanicline 2HCl


    <p>Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.</p>
    Formula:C10H16Cl2N2
    Purity:99.4%
    Color and Shape:Soild
    Molecular weight:235.15
  • Proadrenomedullin (1-20), human

    CAS:
    <p>Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.</p>
    Formula:C112H178N36O27
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2460.84
  • TC-2559 difumarate

    CAS:
    <p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>
    Formula:C20H26N2O9
    Color and Shape:Solid
    Molecular weight:438.43
  • Bensultap

    CAS:
    <p>Bensultap is an agricultural chemical typically used as a pesticide.</p>
    Formula:C17H21NO4S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:431.61
  • Ebiratide

    CAS:
    <p>Ebiratide is an analog of ACTH 4-9.</p>
    Formula:C48H73N11O10S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:996.23
  • GeX-2

    CAS:
    <p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>
    Formula:C103H169N43O27
    Color and Shape:Solid
    Molecular weight:2441.72
  • Aceclidine (hydrochloride)

    CAS:
    <p>agonist of muscarinic receptors</p>
    Formula:C9H16ClNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:205.68
  • Tropicamide

    CAS:
    <p>Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.</p>
    Formula:C17H20N2O2
    Purity:99.78% - 99.94%
    Color and Shape:White Powder
    Molecular weight:284.35
  • Navafenterol

    CAS:
    <p>AZD-8871, a potential COPD and asthma treatment, may work well with ICS.</p>
    Formula:C38H42N6O6S2
    Color and Shape:Solid
    Molecular weight:742.91
  • α-Conotoxin PIA

    CAS:
    <p>Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nM</p>
    Formula:C79H125N27O25S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1981.3
  • (-)-OPC-51803

    CAS:
    <p>(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.</p>
    Formula:C26H32ClN3O2
    Purity:98.73% - 99.59%
    Color and Shape:Soild
    Molecular weight:454
  • (rel)-Asperparaline A

    CAS:
    <p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>
    Formula:C20H29N3O3
    Color and Shape:Solid
    Molecular weight:359.47
  • sabcomeline

    CAS:
    <p>Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.</p>
    Formula:C10H15N3O
    Color and Shape:Solid
    Molecular weight:193.25
  • DSPE-PEG2000-RVG29


    <p>DSPE-PEG2000-RVG29 is a PEG compound composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and can traverse the BBB.</p>
    Color and Shape:Odour Solid
  • Lu AE51090

    CAS:
    <p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>
    Formula:C24H29N3O3
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:407.51
  • 5-AAM-2-CP

    CAS:
    <p>5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.</p>
    Formula:C8H9ClN2O
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:184.62
  • (R)-(+)-Anatabine

    CAS:
    <p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>
    Formula:C10H12N2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:160.22
  • (Rac)-Sabcomeline

    CAS:
    <p>(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.</p>
    Formula:C10H15N3O
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:193.25
  • LAS190792

    CAS:
    <p>LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.</p>
    Formula:C39H43ClN4O9S2
    Color and Shape:Solid
    Molecular weight:811.36
  • Br-PBTC

    CAS:
    <p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>
    Formula:C14H15BrN2OS
    Color and Shape:Solid
    Molecular weight:339.25
  • β2AR/M-receptor agonist-1

    CAS:
    <p>β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and</p>
    Formula:C43H56BrN3O7
    Color and Shape:Solid
    Molecular weight:806.82
  • Dexetimide

    CAS:
    <p>Dexetimide, a muscarinic receptor antagonist, treats neuroleptic-induced parkinsonism.</p>
    Formula:C23H26N2O2
    Color and Shape:Solid
    Molecular weight:362.46
  • Metixene hydrochloride hydrate

    CAS:
    <p>Metixene HCl hydrate is a potential anticholinergic for Parkinson's with IC50 of 55 nM and Ki of 15 nM against muscarine receptors.</p>
    Formula:C20H26ClNOS
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:363.95
  • Fipexide hydrochloride

    CAS:
    <p>Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.</p>
    Formula:C20H22Cl2N2O4
    Color and Shape:Solid
    Molecular weight:425.31
  • NKH477

    CAS:
    <p>NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.</p>
    Formula:C27H44ClNO8
    Purity:98% - 98%
    Color and Shape:Solid
    Molecular weight:546.09
  • Tolterodine

    CAS:
    <p>Tolterodine ((R)-(+)-Tolterodine) is an mACh antagonist used in the treatment of detrusor instability and overactive bladder syndrome.</p>
    Formula:C22H31NO
    Purity:99.71%
    Color and Shape:White Like Or Light Brown Crystalline Powder
    Molecular weight:325.49
  • YM-58790 hydrochloride

    CAS:
    <p>YM-58790 is a potent M3 muscarinic receptor antagonist(Ki of 15 nM).</p>
    Formula:C27H32ClN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:466.02
  • Palmatine hydroxide

    CAS:
    <p>Palmatine hydroxide: oral IDO-1 inhibitor (IC50: 3-157μM), targets WNV protease, has anti-cancer/viral and neuroprotective properties.</p>
    Formula:C21H23NO5
    Color and Shape:Solid
    Molecular weight:369.41
  • Cevimeline

    CAS:
    <p>Cevimeline: muscarinic agonist, treats dry mouth &amp; Sjögren's, boosts saliva post-cancer radiotherapy.</p>
    Formula:C10H17NOS
    Color and Shape:Off-White Solid
    Molecular weight:199.31
  • Pirmenol hydrochloride

    CAS:
    <p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>
    Formula:C22H31ClN2O
    Color and Shape:Solid
    Molecular weight:374.95
  • Varenicline Hydrochloride

    CAS:
    <p>Varenicline Hydrochloride (CP 526555) is an orally active partial agonist of the α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM).</p>
    Formula:C13H14ClN3
    Purity:99.854%
    Color and Shape:Solid
    Molecular weight:247.72
  • Cevimeline hydrochloride

    CAS:
    <p>Cevimeline HCl is a muscarinic agonist enhancing salivary and sweat gland secretion.</p>
    Formula:C10H18ClOS
    Color and Shape:Solid
    Molecular weight:235.77
  • Glycerophosphoinositol choline

    CAS:
    <p>Glycerophosphoinositol choline is the salt of choline and glycerophosphoinositol.</p>
    Formula:C14H32NO12P
    Color and Shape:Solid
    Molecular weight:437.38
  • Ispronicline

    CAS:
    <p>Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive</p>
    Formula:C14H22N2O
    Purity:97.70% - 99.16%
    Color and Shape:Solid
    Molecular weight:234.34
  • Sabcomeline hydrochloride

    CAS:
    <p>Sabcomeline is a selective M1 receptor partial agonist.</p>
    Formula:C10H16ClN3O
    Color and Shape:Solid
    Molecular weight:229.71
  • (±)-Darifenacin

    CAS:
    <p>(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.</p>
    Formula:C28H30N2O2
    Color and Shape:Solid
    Molecular weight:426.55
  • VU0467485

    CAS:
    <p>VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.</p>
    Formula:C17H17FN4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.41
  • Clorprenaline

    CAS:
    <p>Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.</p>
    Formula:C11H16ClNO
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:213.7
  • ABT-107

    CAS:
    <p>ABT-107: α7 neuronal receptor agonist; protects rats' brains from 6-OHDA-induced damage.</p>
    Formula:C19H20N4O
    Color and Shape:Solid
    Molecular weight:320.396