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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 574 products of "AChR"

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  • Ispronicline

    CAS:
    <p>Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive</p>
    Formula:C14H22N2O
    Purity:97.70% - 99.16%
    Color and Shape:Solid
    Molecular weight:234.34
  • Fesoterodine L-mandelate

    CAS:
    <p>Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).</p>
    Formula:C34H45NO6
    Color and Shape:Solid
    Molecular weight:563.735
  • N6-Methyladenosine 5'-monophosphate disodium salt

    CAS:
    <p>N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator and an inhibitor of adenylate kinase II.</p>
    Formula:C11H14N5Na2O7P
    Purity:99.36% - 99.36%
    Color and Shape:Solid
    Molecular weight:405.21
  • Solifenacin D5 hydrochloride

    CAS:
    <p>Solifenacin D5 HCl: deuterium-labeled M1, M2, M3 muscarinic receptor antagonist with pKi 7.6, 6.9, 8.0.</p>
    Formula:C23H27ClN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:403.96
  • Telenzepine dihydrochloride

    CAS:
    <p>muscarinic M1 receptor antagonist</p>
    Formula:C19H23ClN4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.93
  • DL-Cystine

    CAS:
    <p>DL-Cystine is a cysteine derivative that inhibits endothelial cell proliferation by regulating TGFβ1. a GPR inhibitor and nAChR agonist .</p>
    Formula:C6H12N2O4S2
    Color and Shape:Solid
    Molecular weight:240.3
  • Sabcomeline hydrochloride

    CAS:
    <p>Sabcomeline is a selective M1 receptor partial agonist.</p>
    Formula:C10H16ClN3O
    Color and Shape:Solid
    Molecular weight:229.71
  • VU0467485

    CAS:
    <p>VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.</p>
    Formula:C17H17FN4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:360.41
  • Tebanicline dihydrochloride

    CAS:
    <p>Tebanicline dihydrochloride: oral analgesic, nAChR modulator, Ki=37 pM at α4β2 receptors, inhibits cytisine binding.</p>
    Formula:C9H13Cl3N2O
    Color and Shape:Solid
    Molecular weight:271.57
  • (±)-Darifenacin

    CAS:
    <p>(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.</p>
    Formula:C28H30N2O2
    Color and Shape:Solid
    Molecular weight:426.55
  • Pirmenol hydrochloride

    CAS:
    <p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>
    Formula:C22H31ClN2O
    Color and Shape:Solid
    Molecular weight:374.95
  • Cevimeline

    CAS:
    <p>Cevimeline: muscarinic agonist, treats dry mouth &amp; Sjögren's, boosts saliva post-cancer radiotherapy.</p>
    Formula:C10H17NOS
    Color and Shape:Off-White Solid
    Molecular weight:199.31
  • Cevimeline hydrochloride

    CAS:
    <p>Cevimeline HCl is a muscarinic agonist enhancing salivary and sweat gland secretion.</p>
    Formula:C10H18ClOS
    Color and Shape:Solid
    Molecular weight:235.77
  • Darifenacin

    CAS:
    <p>Darifenacin (UK-88525) is a muscarinic receptor M3 antagonist with anticonvulsant activity and can be used to study urinary incontinence and overactive bladder.</p>
    Formula:C28H30N2O2
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:426.55
  • DMAB-anabaseine dihydrochloride

    CAS:
    <p>DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containing</p>
    Formula:C19H23Cl2N3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:364.31
  • Nanofin

    CAS:
    <p>Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.</p>
    Formula:C7H15N
    Purity:97.38% - 99.818%
    Color and Shape:Clear Colorless To Slightly Yellow Liquid
    Molecular weight:113.2
  • Fesoterodine

    CAS:
    <p>Fesoterodine is an oral mAChR blocker (pKi: 7.3-8.0) for M1-M5, used to treat OAB.</p>
    Formula:C26H37NO3
    Purity:97.1%
    Color and Shape:Solid
    Molecular weight:411.58
  • PHA 568487

    CAS:
    <p>PHA 568487: α-7 nAChR agonist, rapid brain uptake, lessens oxidative stress &amp; neuroinflammation.</p>
    Formula:C20H24N2O7
    Color and Shape:Solid
    Molecular weight:404.419
  • Mivacurium dichloride

    CAS:
    <p>Mivacurium dichloride: non-depolarizing, quick-acting muscle relaxant for minor surgeries and tracheal intubation.</p>
    Formula:C58H80Cl2N2O14
    Purity:99.2% - 99.48%
    Color and Shape:Off-White Solid
    Molecular weight:1100.17
  • PSEM 89S TFA

    CAS:
    <p>PSEM 89S TFA is a brain-penetrant and selective ion channels agonist, and is orthogonally selective for Q79G and L141F, respectively.</p>
    Formula:C18H23F3N2O5
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:404.38
  • A-867744

    CAS:
    <p>A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).</p>
    Formula:C20H19ClN2O3S
    Purity:95.66%
    Color and Shape:Solid
    Molecular weight:402.89
  • Cyclopentolate Hydrochloride

    CAS:
    <p>Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.</p>
    Formula:C17H26ClNO3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:327.85
  • Mecamylamine hydrochloride

    CAS:
    <p>Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.</p>
    Formula:C11H22ClN
    Purity:99.76% - >99.99%
    Color and Shape:White Solid
    Molecular weight:203.75
  • Coluracetam

    CAS:
    <p>Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.</p>
    Formula:C19H23N3O3
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:341.4
  • Aclidinium bromide

    CAS:
    <p>Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis.</p>
    Formula:C26H30NO4S2·Br
    Purity:99.53% - 99.69%
    Color and Shape:Solid
    Molecular weight:564.55
  • Rivanicline hemioxalate


    <p>Rivanicline hemioxalate is a selective α4β2 nicotinic receptor agonist (K i =26 nM), over 1,000x preference to α7 (K i =3.6 μM), with limited side effects.</p>
    Formula:C12H16N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:207.23
  • Oxyphencyclimine

    CAS:
    <p>Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.</p>
    Formula:C20H28N2O3
    Color and Shape:Solid
    Molecular weight:344.45
  • Benzetimide hydrochloride

    CAS:
    <p>Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.</p>
    Formula:C23H27ClN2O2
    Purity:99.32%
    Color and Shape:Off-White Powder
    Molecular weight:398.93
  • BQCA

    CAS:
    <p>BQCA (benzylquinolone carboxylic acid) a highly selective allosteric M1 mAChR modulator.</p>
    Formula:C18H15NO4
    Purity:97.22%
    Color and Shape:Solid
    Molecular weight:309.32
  • Oxyphencyclimine Hydrochloride

    CAS:
    <p>Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.</p>
    Formula:C20H29ClN2O3
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:380.91
  • LY2119620

    CAS:
    <p>LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.</p>
    Formula:C19H24ClN5O3S
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:437.94
  • Thiacloprid

    CAS:
    <p>Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.</p>
    Formula:C10H9ClN4S
    Purity:98.66% - 99.95%
    Color and Shape:Yellowish Crystalline Powder
    Molecular weight:252.72
  • Propantheline

    CAS:
    <p>Propantheline: oral muscarinic receptor blocker for smooth muscle issues, hyperhidrosis, and bladder control.</p>
    Formula:C23H30NO3
    Color and Shape:Solid
    Molecular weight:368.49
  • Encenicline

    CAS:
    <p>Encenicline (EVP-6124), a selective α7 nAChRs agonist, targets cognitive impairment in schizophrenia and Alzheimer's.</p>
    Formula:C16H17ClN2OS
    Purity:99.20%
    Color and Shape:Solid
    Molecular weight:320.84
  • Pirmenol

    CAS:
    <p>Pirmenol is a new antiarrhythmic drug</p>
    Formula:C22H30N2O
    Purity:97.24%
    Color and Shape:Solid
    Molecular weight:338.49
  • NS3861

    CAS:
    <p>NS3861 is a selective agonist for α3β4/α4β2 nAChRs, preferring β-subunits, with no effect on α4-based receptors.</p>
    Formula:C12H14BrNS
    Purity:99.853%
    Color and Shape:Solid
    Molecular weight:284.22
  • Ursulcholic acid

    CAS:
    <p>Ursulcholic acid (Ursulcholic) is a water-soluble anticholinergic compound.</p>
    Formula:C24H40O10S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:552.7
  • Ilmetropium iodide

    CAS:
    <p>Ilmetropium iodide is a bronchodilator.</p>
    Formula:C20H30INO3
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:459.36
  • Propiverine

    CAS:
    <p>Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.</p>
    Formula:C23H29NO3
    Color and Shape:Solid
    Molecular weight:367.48
  • JHU37160

    CAS:
    <p>JHU37160 is a DREADD agonist with Ki of 1.9 nM for hM3Dq, 3.6 nM for hM4Di, and EC50 of 18.5 nM (hM3Dq), 0.2 nM (hM4Di) in HEK-293 cell assays.</p>
    Formula:C19H20ClFN4
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:358.84
  • OXOMEMAZINE

    CAS:
    <p>Oxomemazine: a phenothiazine antihistamine H1-blocker with strong antimuscarinic and selective M1 antagonist properties, used in cough research.</p>
    Formula:C18H22N2O2S
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:330.44
  • Mecamylamine

    CAS:
    <p>Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.</p>
    Formula:C11H21N
    Color and Shape:Solid
    Molecular weight:167.29
  • Methylbenactyzium Bromide

    CAS:
    <p>Methylbenactyzium Bromide (Semulgin) is an anticonvulsant that is the active metabolite of trimethadione.</p>
    Formula:C21H28BrNO3
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:422.36
  • SEN12333

    CAS:
    <p>SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist</p>
    Formula:C20H25N3O2
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:339.43
  • Solifenacin hydrochloride

    CAS:
    <p>Solifenacin Hcl is a muscarinic receptor antagonist.</p>
    Formula:C23H27ClN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.93
  • Varenicline dihydrochloride

    CAS:
    <p>Varenicline dihydrochloride is a Selective α4β2 nicotinic acetylcholine receptor partial agonist.</p>
    Formula:C13H15Cl2N3
    Purity:99.88% - 99.97%
    Color and Shape:Solid
    Molecular weight:284.18
  • Brompheniramine

    CAS:
    <p>Brompheniramine, an alkylamine antihistamine, targets H1 receptors (Kd=6.06nM) and has anticholinergic/depressant qualities. Blocks Ca/Na/hERG channels.</p>
    Formula:C16H19BrN2
    Color and Shape:Solid
    Molecular weight:319.24
  • Imidafenacin

    CAS:
    <p>Imidafenacin (KRP-197)(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.</p>
    Formula:C20H21N3O
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:319.4
  • Donepezil Hydrochloride

    CAS:
    <p>Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).</p>
    Formula:C24H29NO3·HCl
    Purity:99.55% - 99.8%
    Color and Shape:White To Off-White Crystalline Solid
    Molecular weight:415.96
  • 4BP-TQS

    CAS:
    <p>4BP-TQS is an allosteric agonist of α7 nAChRs.</p>
    Formula:C18H17BrN2O2S
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:405.31
  • Isopropamide Iodide

    CAS:
    <p>Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.</p>
    Formula:C23H33IN2O
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:480.43
  • SQ22536

    CAS:
    <p>SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.</p>
    Formula:C9H11N5O
    Purity:99.18%
    Color and Shape:Off-White Solid
    Molecular weight:205.22
  • Tacrine hydrochloride (hydrate)

    CAS:
    <p>Tacrine hydrochloride hydrate (Tetrahydroaminacrine) is a cholinesterase inhibitor that crosses the blood-brain barrier.</p>
    Formula:C13H14N2·XHCl·XH2O
    Purity:99.01% - 99.89%
    Color and Shape:Solid
    Molecular weight:234.72
  • A 582941 HCl (848591-90-2(free base))


    <p>A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties</p>
    Formula:C17H21ClN4
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:316.83
  • ML380

    CAS:
    <p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>
    Formula:C23H25F3N4O3S
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:494.53
  • Atracurium besylate

    CAS:
    <p>Atracurium besylate (51W89) is a short-acting, non-depolarizing muscle relaxant, not affecting the heart or reliant on kidneys.</p>
    Formula:C65H82N2O18S2
    Purity:98.94% - 99.71%
    Color and Shape:Solid
    Molecular weight:1243.49
  • VU0467154

    CAS:
    <p>VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.</p>
    Formula:C17H15F3N4O3S2
    Purity:98.28% - 99.51%
    Color and Shape:Solid
    Molecular weight:444.45
  • suvn-911

    CAS:
    <p>suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.</p>
    Formula:C11H14Cl2N2O
    Purity:98.88%
    Color and Shape:Solid
    Molecular weight:261.15
  • 9-Ethyladenine

    CAS:
    <p>9-Ethyladenine (6-Amino-9-ethylpurine) is a partially potent APRT (adenine phosphoribosyltransferase) inhibitor [1].</p>
    Formula:C7H9N5
    Purity:99.35% - 99.41%
    Color and Shape:Solid
    Molecular weight:163.18
  • VU0152099

    CAS:
    <p>VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).</p>
    Formula:C18H17N3O3S
    Purity:98.46%
    Color and Shape:Solid
    Molecular weight:355.41
  • VU0152100

    CAS:
    <p>VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).</p>
    Formula:C18H19N3O2S
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:341.43
  • TBPB

    CAS:
    <p>TBPB is an allosteric M1 mAChR agonist.</p>
    Formula:C25H32N4O
    Purity:97.87% - 99.9%
    Color and Shape:Solid
    Molecular weight:404.55
  • Tebanicline hydrochloride

    CAS:
    <p>Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.</p>
    Formula:C9H12Cl2N2O
    Purity:91.74% - 98.71%
    Color and Shape:Solid
    Molecular weight:235.11
  • Ipratropium Bromide

    CAS:
    <p>Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.</p>
    Formula:C20H30BrNO3
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:412.37
  • VU0119498

    CAS:
    <p>VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.</p>
    Formula:C15H10BrNO2
    Purity:97.56%
    Color and Shape:Solid
    Molecular weight:316.15
  • Dicyclomine

    CAS:
    <p>Dicyclomine: oral muscarinic antagonist, eases GI muscle spasms, high affinity for M1/M2 receptors, Ki of 5.1 nM/54.6 nM.</p>
    Formula:C19H35NO2
    Color and Shape:Solid
    Molecular weight:309.49
  • Batefenterol

    CAS:
    <p>Batefenterol (GSK961081) is a muscarinic antagonist and β2-agonist with high affinity (Ki: 1.4/1.3/3.7 nM).</p>
    Formula:C40H42ClN5O7
    Purity:97.94% - 98.4%
    Color and Shape:Solid
    Molecular weight:740.24
  • KH7

    CAS:
    <p>KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific.</p>
    Formula:C17H15BrN4O2S
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:419.3
  • Piperidolate hydrochloride

    CAS:
    <p>Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.</p>
    Formula:C21H26ClNO2
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:359.89
  • Bestim

    CAS:
    <p>Bestim is an immunomodulatory dipeptide that is synthetic.</p>
    Formula:C16H19N3O5
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:333.34
  • VU0357017 hydrochloride

    CAS:
    <p>VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.</p>
    Formula:C18H28ClN3O3
    Purity:99% - 99.97%
    Color and Shape:Solid
    Molecular weight:369.89
  • Succinylcholine Chloride Dihydrate

    CAS:
    <p>Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.</p>
    Formula:C14H30N2O4·2Cl·2H2O
    Purity:99.87%
    Color and Shape:White Solid
    Molecular weight:397.34
  • VU10010

    CAS:
    <p>VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.</p>
    Formula:C17H16ClN3OS
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:345.85
  • Procyclidine hydrochloride

    CAS:
    <p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>
    Formula:C19H30ClNO
    Purity:99.24% - 99.88%
    Color and Shape:Crystals From Petroleum Ether White Powder
    Molecular weight:323.9
  • Oxotremorine sesquifumarate

    CAS:
    <p>Oxotremorine sesquifumarate is a muscarinic agonist.</p>
    Formula:C12H18N2OC4H4O4
    Purity:97.94%
    Color and Shape:Solid
    Molecular weight:380.39
  • α-Conotoxin MII acetate


    <p>α-Conotoxin MII acetate is a 16-amino acid peptide from the venom of the marine snail Conus magus.</p>
    Formula:C69H107N23O24S4
    Purity:94.82% - 97.79%
    Color and Shape:Solid
    Molecular weight:1770.99
  • Syn-Ake acetate

    CAS:
    <p>Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.</p>
    Formula:C19H29N5O3·2(C2H4O2)
    Purity:99.60%
    Color and Shape:Solid
    Molecular weight:495.58
  • Clothianidin

    CAS:
    <p>Clothianidin (TI 435), an insecticide, stimulates nAChR as acetylcholine agonist, not AChE inhibitor.</p>
    Formula:C6H8ClN5O2S
    Purity:99.71% - 99.87%
    Color and Shape:Solid Powder
    Molecular weight:249.68
  • JHU37152

    CAS:
    <p>JHU37152 is a DREADD agonist; Ki: 1.8 nM at hM3Dq, 8.7 nM at hM4Di; EC50: 5 nM (hM3Dq), 0.5 nM (hM4Di) in HEK-293 cell assays.</p>
    Formula:C19H20ClFN4
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:358.84
  • Varenicline Tartrate

    CAS:
    <p>Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.</p>
    Formula:C13H13N3·C4H6O6
    Purity:98.23% - 98.32%
    Color and Shape:Tan Solid
    Molecular weight:361.35
  • TQS

    CAS:
    <p>TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.</p>
    Formula:C22H20N2O2S
    Purity:98.56%
    Color and Shape:Solid
    Molecular weight:376.47
  • Sofpironium bromide

    CAS:
    <p>Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine.</p>
    Formula:C22H32BrNO5
    Purity:98.85%
    Color and Shape:Solid
    Molecular weight:470.4
  • Dinotefuran

    CAS:
    <p>Dinotefuran (MTI-446), a neonicotinoid insecticide, targets pests by blocking their nervous system.</p>
    Formula:C7H14N4O3
    Purity:99.89%
    Color and Shape:White Crystalline Powder
    Molecular weight:202.21
  • MC-Val-Cit-PAB

    CAS:
    <p>MC-Val-Cit-PAB: cathepsin-cleavable ADC linker used in FDA-approved brentuximab vedotin.</p>
    Formula:C28H40N6O7
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:572.65
  • Revefenacin

    CAS:
    <p>Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.</p>
    Formula:C35H43N5O4
    Purity:98.12%
    Color and Shape:Solid
    Molecular weight:597.75
  • Pempidine

    CAS:
    <p>Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.</p>
    Formula:C10H21N
    Purity:98.18% - 99.28%
    Color and Shape:Colorless - Light Yellow Clear Liquid
    Molecular weight:155.28
  • Dronedarone

    CAS:
    <p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>
    Formula:C31H44N2O5S
    Purity:98.85% - 99.58%
    Color and Shape:Solid
    Molecular weight:556.76
  • Nitrocaramiphen hydrochloride

    CAS:
    <p>Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.</p>
    Formula:C18H27ClN2O4
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:370.87
  • Anisotropine Methylbromide

    CAS:
    <p>Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.</p>
    Formula:C17H32BrNO2
    Purity:99.73%
    Color and Shape:Crystals From Acetone Solid
    Molecular weight:362.35
  • Solifenacin

    CAS:
    <p>Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,</p>
    Formula:C23H26N2O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:362.46
  • Piperidolate

    CAS:
    <p>Piperidolate inhibits intestinal cramp induced by acetylcholine</p>
    Formula:C21H25NO2
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:323.43
  • PNU-282987 S enantiomer free base

    CAS:
    <p>PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).</p>
    Formula:C14H17ClN2O
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:264.75
  • VU 0238429

    CAS:
    <p>VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).</p>
    Formula:C17H12F3NO4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:351.28
  • VU0238441

    CAS:
    <p>VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.</p>
    Formula:C16H9ClF3NO2
    Purity:100%
    Color and Shape:Solid
    Molecular weight:339.7
  • Glycopyrrolate

    CAS:
    <p>Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.</p>
    Formula:C19H28BrNO3
    Purity:99.41% - 99.64%
    Color and Shape:Solid
    Molecular weight:398.33
  • PHA 543613 hydrochloride

    CAS:
    <p>PHA-543613 hydrochloride, a potent α7 nicotinic receptor agonist, may treat schizophrenia-related cognitive deficits.</p>
    Formula:C15H18ClN3O2
    Color and Shape:Solid
    Molecular weight:307.78
  • Nitenpyram

    CAS:
    <p>Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.</p>
    Formula:C11H15ClN4O2
    Purity:99.03%
    Color and Shape:Light-Yellow Crystal
    Molecular weight:270.72
  • Harman hydrochloride

    CAS:
    <p>Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.</p>
    Formula:C12H11ClN2
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:218.68
  • CCMI

    CAS:
    <p>CCMI (AVL-3288) is a potent and selective modulator of α7 nAChR-positive allosteric.</p>
    Formula:C19H15Cl2N3O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:388.25
  • W-84 dibromide

    CAS:
    <p>W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.</p>
    Formula:C32H44Br2N4O4
    Purity:95.56%
    Color and Shape:Solid
    Molecular weight:708.52
  • BNC210

    CAS:
    <p>BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.</p>
    Formula:C17H23N3O3
    Purity:97.05% - >99.99%
    Color and Shape:Solid
    Molecular weight:317.38
  • Prifinium bromide

    CAS:
    <p>Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action.</p>
    Formula:C22H28BrN
    Purity:97.99%
    Color and Shape:Solid
    Molecular weight:386.37
  • Nor-benzetimide

    CAS:
    <p>Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.</p>
    Formula:C16H20N2O2
    Purity:98.63%
    Color and Shape:Solid
    Molecular weight:272.34
  • NS 1738

    CAS:
    <p>NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)</p>
    Formula:C14H9Cl2F3N2O2
    Purity:99.11%
    Color and Shape:Solid
    Molecular weight:365.13
  • Cyclodrine hydrochloride

    CAS:
    <p>Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that can be used in the study of</p>
    Formula:C19H30ClNO3
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:355.9
  • Pozanicline dihydrochloride

    CAS:
    <p>Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)</p>
    Formula:C11H18Cl2N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:265.18
  • (-)-(S)-B-973B

    CAS:
    <p>(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.</p>
    Formula:C24H26F2N6O
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:452.5
  • ST034307

    CAS:
    <p>ST034307 is an effective and selective inhibitor of adenylyl cyclase 1 (IC50: 2.3 μM).</p>
    Formula:C10H4Cl4O2
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:297.95
  • Oxyphenonium bromide

    CAS:
    <p>Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.</p>
    Formula:C21H34BrNO3
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:428.404
  • Umeclidinium bromide

    CAS:
    <p>Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist.</p>
    Formula:C29H34BrNO2
    Purity:98.4% - 99.89%
    Color and Shape:Solid
    Molecular weight:508.49
  • Nitrobenzylthioinosine

    CAS:
    <p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>
    Formula:C17H17N5O6S
    Purity:99.69% - 99.74%
    Color and Shape:Off-White Solid
    Molecular weight:419.41
  • PHA 568487 free base

    CAS:
    <p>PHA 568487 free base, an α7 nicotinic receptor agonist, designed to reduce bioactivation and improve in vivo tolerability.</p>
    Formula:C16H20N2O3
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:288.34
  • mAChR-IN-1 hydrochloride

    CAS:
    <p>mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.</p>
    Formula:C23H26ClIN2O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:524.82
  • NS9283

    CAS:
    <p>NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.</p>
    Formula:C14H8N4O
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:248.24
  • PNU-120596

    CAS:
    <p>PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.</p>
    Formula:C13H14ClN3O4
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:311.72
  • MC-Val-Cit-PABC-PNP

    CAS:
    <p>MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.</p>
    Formula:C35H43N7O11
    Purity:97.2% - 98.055%
    Color and Shape:Solid
    Molecular weight:737.76
  • Ethyl (triphenylphosphoranylidene) acetate

    CAS:
    <p>Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.</p>
    Formula:C22H21O2P
    Purity:97.985%
    Color and Shape:White Or Slight Yellow Powder
    Molecular weight:348.37
  • Blarcamesine

    CAS:
    <p>Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.</p>
    Formula:C19H23NO
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:281.39
  • Encenicline hydrochloride

    CAS:
    <p>Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).</p>
    Formula:C16H17ClN2OS·HCl
    Purity:98.34% - 99.85%
    Color and Shape:Solid
    Molecular weight:357.3
  • (S)-UFR2709

    CAS:
    <p>(S)-UFR2709, a nAChR competitive antagonist, favors α4β2 over α7, reduces anxiety and alcohol use in rats.</p>
    Formula:C13H17NO2
    Color and Shape:Solid
    Molecular weight:219.284
  • Mc-​Val-​Ala-​PAB

    CAS:
    <p>Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).</p>
    Formula:C25H34N4O6
    Purity:98.34% - 99.24%
    Color and Shape:Solid
    Molecular weight:486.56
  • Pipecuronium bromide

    CAS:
    <p>Pipecuronium bromide (RGH-1106) is an nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker that causes muscle relaxation.</p>
    Formula:C35H62Br2N4O4
    Purity:>99.99%
    Color and Shape:Powder
    Molecular weight:762.7
  • Velufenacin

    CAS:
    <p>Velufenacin is an antagonist of muscarinic receptor[1].</p>
    Formula:C19H20ClFN2O2
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:362.83
  • Pentoxyverine

    CAS:
    <p>Pentoxyverine (Carbetapentan) is an orally available cough suppressant, an antagonist of muscarinic receptor M1 and an agonist of the σ1 receptor.</p>
    Formula:C20H31NO3
    Purity:97.11%
    Color and Shape:Solid
    Molecular weight:333.47
  • Mepenzolate Bromide

    CAS:
    <p>Mepenzolate Bromide (Colibantil) is a muscarinic antagonist used to treat gastrointestinal conditions.</p>
    Formula:C21H26BrNO3
    Purity:95.73% - 99.21%
    Color and Shape:Solid
    Molecular weight:420.34
  • AF-710B

    CAS:
    <p>AF710B is an enantiomer of AF710. AF-710B is also a sigma and M1 muscarinic receptors agonist.</p>
    Formula:C20H27N3OS
    Purity:98.62% - 99.89%
    Color and Shape:Solid
    Molecular weight:357.51
  • Monepantel

    CAS:
    <p>Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.</p>
    Formula:C20H13F6N3O2S
    Purity:99.83%
    Color and Shape:White Powder
    Molecular weight:473.39
  • Xanomeline tartrate

    CAS:
    <p>Xanomeline tartrate (LY 246708 tartrate) 是 M1和 M4 mAChR 激动剂,具有抗精神病样活性,可改善认知,可用于研究精神分裂症和阿尔茨海默病。</p>
    Formula:C18H29N3O7S
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:431.5
  • Varenicline

    CAS:
    <p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>
    Formula:C13H13N3
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:211.26
  • Pyrantel

    CAS:
    <p>Pyrantel: Nicotinic agonist; causes spastic paralysis in nematodes by depolarizing block.</p>
    Formula:C11H14N2S
    Purity:98%
    Color and Shape:Crystals From Methanol Yellowish Crystalline Powder
    Molecular weight:206.31
  • Atropine hydrobromide

    CAS:
    <p>Atropine hydrobromide is a biochemical.</p>
    Formula:C17H24BrNO3
    Color and Shape:Solid
    Molecular weight:370.28
  • Flavoxate

    CAS:
    <p>Flavoxate is an anticholinergic with antimuscarinic effects.</p>
    Formula:C24H25NO4
    Color and Shape:Solid
    Molecular weight:391.46
  • Anatabine dicitrate


    <p>Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.</p>
    Formula:C22H28N2O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:544.46
  • Oxantel

    CAS:
    <p>Oxantel is a fumarate reductase inhibitor with anthelmintic activity.</p>
    Formula:C13H16N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:216.28
  • Biperiden lactate

    CAS:
    <p>Biperiden lactate is a biochemical.</p>
    Formula:C24H35NO4
    Color and Shape:Solid
    Molecular weight:401.54
  • Catestatin

    CAS:
    <p>Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.</p>
    Formula:C107H173N37O26S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2425.84
  • VU0029767

    CAS:
    <p>VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.</p>
    Formula:C21H21N3O3
    Color and Shape:Solid
    Molecular weight:363.41
  • Diphenidol

    CAS:
    <p>Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent.</p>
    Formula:C21H27NO
    Color and Shape:Needles From Petroleum Ether Solid
    Molecular weight:309.45
  • Azacyclonol hydrochloride

    CAS:
    <p>Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.</p>
    Formula:C18H22ClNO
    Color and Shape:Off White Crystalline Powder
    Molecular weight:303.83
  • Dianicline dihydrochloride

    CAS:
    <p>Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.</p>
    Formula:C13H16N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:216.28
  • Aprofene

    CAS:
    <p>Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.</p>
    Formula:C21H27NO2
    Color and Shape:Solid
    Molecular weight:325.44
  • Sulindac sulfide

    CAS:
    <p>Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.</p>
    Formula:C20H17FO2S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:340.41
  • N-0861 racemate

    CAS:
    <p>N-0861 racemate is the racemate of N-0861.</p>
    Formula:C13H17N5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:243.31
  • Sulfoxaflor

    CAS:
    <p>Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.</p>
    Formula:C10H10F3N3OS
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:277.27
  • Sch412348

    CAS:
    <p>Sch412348: potent A2A receptor antagonist, Ki=0.6 nM, &gt;1000-fold selectivity vs. other adenosine receptors.</p>
    Formula:C22H21F2N9O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:465.46
  • SR 16584

    CAS:
    <p>α3β4 nAChR antagonist</p>
    Formula:C17H22N2O
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:270.37
  • Tarafenacin

    CAS:
    <p>Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.</p>
    Formula:C21H20F4N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:408.39
  • Meseclazone

    CAS:
    <p>Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.</p>
    Formula:C11H10ClNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:239.65
  • 4-DAMP

    CAS:
    <p>4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.</p>
    Formula:C21H26INO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:451.34
  • mAChr-in-1

    CAS:
    <p>mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).</p>
    Formula:C23H25IN2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:488.36
  • Darenzepine

    CAS:
    <p>Darenzepine is a muscarinic receptor inhibitor.</p>
    Formula:C21H21N3O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:347.41
  • UB 165 fumarate

    CAS:
    <p>UB 165 fumarate is a nAChR agonist, α4β2 partial, α3β2 full, with a 0.27 nM Ki for [3H]-nicotine in rat brain.</p>
    Formula:C17H19ClN2O4
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:350.8
  • CDD0102

    CAS:
    <p>CDD0102 is a potent agonist of M1 Muscarinic receptor.</p>
    Formula:C8H12N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:180.21
  • 5-Iodo-A-85380 dihydrochloride

    CAS:
    <p>α4β2 and α6β2 nicotinic acetylcholine receptors agonist</p>
    Formula:C9H13Cl2IN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:363.02
  • Dimethyl-W84 (dibromide)

    CAS:
    <p>Dimethyl-W84, selective M2 muscarinic receptor modulator; slows N-methylscopolamine release, EC50=3 nM.</p>
    Formula:C34H48Br2N4O4
    Color and Shape:Solid
    Molecular weight:736.59
  • LY 2087101

    CAS:
    <p>Allosteric potentiator of α7, α4β2 and α4β4 nAChRs</p>
    Formula:C15H11FN2OS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:318.39
  • AR-R 17779 hydrochloride

    CAS:
    <p>AR-R17779 hydrochloride: potent α7 nAChR agonist; K i : 92 nM (α7), 16,000 nM (α4β2); enhances rat cognition; anxiolytic; anti-inflammatory.</p>
    Formula:C9H15ClN2O2
    Color and Shape:Solid
    Molecular weight:218.68
  • Elucaine

    CAS:
    <p>Elucaine is an antagonist of the muscarinic acetylcholine receptor. It has anti-ulcerative activity.</p>
    Formula:C19H23NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:297.39
  • (R,R)-Glycopyrrolate

    CAS:
    <p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>
    Formula:C19H28BrNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.34
  • SIB 1508Y maleate

    CAS:
    <p>neuronal nicotinic ACh receptor agonist</p>
    Formula:C16H18N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:302.33
  • LRE1

    CAS:
    <p>LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor.</p>
    Formula:C12H13ClN4S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:280.78
  • Terodiline

    CAS:
    <p>Terodiline is an orally available selective muscarinic M1 receptor and calcium channel antagonist for the study of diseases caused by abnormal bladder function.</p>
    Formula:C20H27N
    Purity:98.20% - 99.59%
    Color and Shape:Solid
    Molecular weight:281.44
  • Methacholine bromide

    CAS:
    <p>Methacholine bromide is a potent M3 agonist for diagnosing asthma by identifying bronchial hyperresponsiveness.</p>
    Formula:C8H18BrNO2
    Color and Shape:Solid
    Molecular weight:240.141
  • Nuvenzepine

    CAS:
    <p>Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.</p>
    Formula:C19H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.39
  • DA 4626

    CAS:
    <p>DA 4626 is an H2-receptor antagonist with KB values akin to those in standard assays.</p>
    Formula:C14H18N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:242.32
  • Telenzepine

    CAS:
    <p>Telenzepine is a potent and selective M1 antimuscarinic.</p>
    Formula:C19H22N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:370.47
  • AC260584

    CAS:
    <p>AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).</p>
    Formula:C20H29FN2O2
    Color and Shape:Solid
    Molecular weight:348.45
  • Neramexane Mesylate

    CAS:
    <p>Neramexane: NMDA &amp; nicotinic receptor blocker with neuroprotective, antidepressant, and cognitive-enhancing effects.</p>
    Formula:C12H27NO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:265.41
  • Chlorisondamine diiodide

    CAS:
    <p>long lasting nicotinic antagonist</p>
    Formula:C14H20Cl4I2N2
    Color and Shape:Solid
    Molecular weight:611.94
  • ML381

    CAS:
    <p>ML381 is a M5-orthosteric antagonist with a high selectivity of muscarinic subtype.</p>
    Formula:C21H21N3O4
    Color and Shape:Solid
    Molecular weight:379.41
  • ML169

    CAS:
    <p>ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM).</p>
    Formula:C21H17BrFN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.34
  • Zamifenacin

    CAS:
    <p>Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.</p>
    Formula:C27H29NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:415.52
  • BNC375

    CAS:
    <p>BNC375 is a α7 nAChRs type I positive allosteric modulator (EC50: 1.9 μM).</p>
    Formula:C19H23ClN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:394.92
  • (R,R)-Reboxetine mesylate

    CAS:
    <p>(R,R)-Reboxetine mesylate: Antidepressant, high bioavailability, (R,R) enantiomer, selective for noradrenaline, low toxicity.</p>
    Formula:C20H27NO6S
    Color and Shape:Solid
    Molecular weight:409.5
  • M1 ligand 1

    CAS:
    <p>Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.</p>
    Formula:C20H21NO2
    Color and Shape:Solid
    Molecular weight:307.39
  • Benzatropine

    CAS:
    <p>Benzatropine: Central muscarinic blocker, inhibits dopamine uptake, treats Parkinson's symptoms.</p>
    Formula:C21H25NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:307.43
  • Muscarine iodide

    CAS:
    <p>Muscarinic acetylcholine receptor agonist</p>
    Formula:C9H20INO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:301.17
  • Tridihexethyl chloride

    CAS:
    <p>Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease.</p>
    Formula:C21H36ClNO
    Color and Shape:Solid
    Molecular weight:353.97
  • TC 2559 difumarate

    CAS:
    <p>partial agonist of α4β2 nicotinic acetylcholine receptor</p>
    Formula:C12H18N2OC4H404
    Purity:98%
    Color and Shape:Solid
    Molecular weight:380.39
  • TC299423

    CAS:
    <p>TC299423 is a novel agonist for nicotinic acetylcholine receptors (nAChRs). TC299423 modestly selectively targets α6β2 subtype.</p>
    Formula:C11H15N3
    Color and Shape:Solid
    Molecular weight:189.26
  • SM-21 maleate

    CAS:
    <p>Increases release of acetylcholine,σ2 antagonist</p>
    Formula:C22H28ClNO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.91
  • TC 1698 dihydrochloride

    CAS:
    <p>nicotinic α7 receptor agonist</p>
    Formula:C13H18N2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:202.3
  • Beperidium iodide

    CAS:
    <p>Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93).</p>
    Formula:C23H34IN3O3
    Color and Shape:Solid
    Molecular weight:527.44
  • WIN 62,577

    CAS:
    <p>WIN 62,577 is a allosteric antagonist of mAChR.</p>
    Formula:C29H31N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:437.58
  • Benzamide Derivative 1

    CAS:
    <p>Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.</p>
    Formula:C22H34ClN3O3
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:423.98
  • Alvameline

    CAS:
    <p>Alvameline (Lu25-109) is a partial M1 agonist. Alvameline (Lu25-109) also is a M2/M3 antagonist.</p>
    Formula:C9H15N5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:193.25
  • Muscarine chloride

    CAS:
    <p>Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>
    Formula:C9H20ClNO2
    Color and Shape:Solid
    Molecular weight:209.71
  • Quifenadine

    CAS:
    <p>Quifenadine, an H1-histamine receptor blocker, has antiarrhythmic properties.</p>
    Formula:C20H23NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:293.4
  • DAU 5884 hydrochloride

    CAS:
    <p>muscarinic M3 receptor antagonist</p>
    Formula:C17H22ClN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:351.83
  • Nelonicline

    CAS:
    <p>Nelonicline is a selective agonist of neuronal nicotinic receptors.</p>
    Formula:C17H19N3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:313.42
  • BTM-1086

    CAS:
    <p>BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.</p>
    Formula:C21H25N3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:367.51
  • CP-601932

    CAS:
    <p>CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.</p>
    Formula:C12H12F3N
    Color and Shape:Solid
    Molecular weight:227.23
  • Eucatropine

    CAS:
    <p>Eucatropine, an anticholinergic agent, acts as a potent inhibitor of the muscarinic acetylcholine receptor (mAChR) with an IC 50 value of 0.583 μM.</p>
    Formula:C17H25NO3
    Color and Shape:Solid
    Molecular weight:291.39
  • Thiochrome

    CAS:
    <p>Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.</p>
    Formula:C12H14N4OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:262.33
  • VU0090157

    CAS:
    <p>VU0090157, a novel allosteric potentiators of M1 muscarinic receptor, may provide novel treatments for schizophrenia and Alzheimer's disease.</p>
    Formula:C19H21N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:403.39
  • S-(+)-Mecamylamine hydrochloride

    CAS:
    <p>Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity.</p>
    Formula:C11H22ClN
    Color and Shape:Solid
    Molecular weight:203.75
  • T761-0184

    CAS:
    <p>T761-0184 is a potent antagonist of α7 nicotinic receptor (nAChR) [1].</p>
    Formula:C16H20FN3O
    Color and Shape:Solid
    Molecular weight:289.35
  • Revatropate

    CAS:
    <p>Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.</p>
    Formula:C19H27NO4S
    Color and Shape:Solid
    Molecular weight:365.49
  • Rispenzepine

    CAS:
    <p>Rispenzepine, a novel mAChRs M1/M3 antagonist, treats immune, infections, and respiratory issues.</p>
    Formula:C19H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.39
  • Milameline

    CAS:
    <p>Milameline is a muscarinic receptor agonist that improves cognition.</p>
    Formula:C8H14N2O
    Color and Shape:Solid
    Molecular weight:154.21