AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 625 products for "AChR".
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8-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Formula:C5H6N6Purity:99.82%Color and Shape:SolidMolecular weight:150.14Dicyclomine hydrochloride
CAS:Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.Formula:C19H36ClNO2Purity:99.81%Color and Shape:SolidMolecular weight:345.948Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Formula:C20H26ClNO2Purity:97.76% - 99.53%Color and Shape:White Or Almost White PowderMolecular weight:347.879TAK-071
CAS:TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).Formula:C24H24FN3O3Purity:98.02% - 99.82%Color and Shape:SolidMolecular weight:421.4641Nefiracetam
CAS:Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Formula:C14H18N2O2Purity:97.37%Color and Shape:SolidMolecular weight:246.3TDI-10229
CAS:TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.Formula:C16H16ClN5Purity:99.85% - 99.89%Color and Shape:White SolidMolecular weight:313.785Rivanicline hydrochloride
Rivanicline (RJR-2403) hydrochloride is an agonist of neuronal nicotinic receptors. It shows high selectivity for nAChR in the rat cerebral cortex (Ki= 26 nM, EC50= 732 nM) and the α4β2 subtype (Ki= 26 nM, EC50= 16 μM). This compound effectively restores learning and cognitive function impairments and is applicable in research on neurodegenerative diseases such as schizophrenia or Alzheimer's disease.M3/PDE4 modulator-1
M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.Formula:C38H41Cl2N3O8SColor and Shape:SolidMolecular weight:770.72Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurity:99.63% - 99.96%Color and Shape:White SolidMolecular weight:390.4021Guvacoline hydrobromide
CAS:Guvacoline hydrobromide is a pyridine alkaloid and a full agonist of mAChR in the atrium and ileum.Formula:C7H12BrNO2Purity:98%Color and Shape:White SolidMolecular weight:222.08N-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Formula:C8H12N2Purity:99.65%Color and Shape:SolidMolecular weight:136.1943Navafenterol
CAS:AZD-8871, a potential COPD and asthma treatment, may work well with ICS.Formula:C38H42N6O6S2Color and Shape:SolidMolecular weight:742.91Hydroxybupropion
CAS:Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).Formula:C13H18ClNO2Purity:99.73%Color and Shape:Off-White SolidMolecular weight:255.741GeX-2
CAS:GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.Formula:C103H169N43O27Color and Shape:SolidMolecular weight:2441.72ANQ-9040
CAS:ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.Formula:C36H58N2O5SColor and Shape:SolidMolecular weight:630.92Octamylamine
CAS:Octamylamine is a bioactive chemical.Formula:C13H29NColor and Shape:SolidMolecular weight:199.3761Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Formula:C10H12N2Color and Shape:SolidMolecular weight:160.22nAChR agonist 2
CAS:Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,Formula:C11H16N2Color and Shape:SolidMolecular weight:176.263LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.Formula:C86H121N25O22S4Color and Shape:SolidMolecular weight:1985.31M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Color and Shape:SolidMolecular weight:315.45
