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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 625 products for "AChR".

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  • CymitQuimica logo
    Targetmol
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    PTI-125 HCl

    PTI-125 HCl (Simufilamum HCl) binds and reverses an altered conformation of the scaffolding protein filamin A found in Alzheimer's disease brain.
    Formula:C15H22ClN3O
    Purity:99.64%
    Molecular weight:295.81

    Ref: TM-T9569L

  • Perindoprilat
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    Perindoprilat

    CAS:
    Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.
    Formula:C17H28N2O5
    Purity:99.21%
    Color and Shape:White Solid
    Molecular weight:340.41

    Ref: TM-T1484

  • Methylatropine (nitrate)
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    Methylatropine (nitrate)

    CAS:
    Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.
    Formula:C18H26N2O6
    Color and Shape:Solid
    Molecular weight:366.414

    Ref: TM-T36204

  • nAChR modulator-1
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    nAChR modulator-1

    CAS:
    nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .
    Formula:C12H8ClN3O2
    Color and Shape:Solid
    Molecular weight:261.66

    Ref: TM-T74396

  • ANQ-9040
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    ANQ-9040

    CAS:
    ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.
    Formula:C36H58N2O5S
    Color and Shape:Solid
    Molecular weight:630.92

    Ref: TM-T30079

  • (S)-OPC-51803
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    (S)-OPC-51803

    CAS:
    (S)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.
    Formula:C19H16N2O2
    Purity:98.73% - 99.59%
    Color and Shape:White Solid
    Molecular weight:304.3425

    Ref: TM-T28257L

  • Lu AE51090
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    Lu AE51090

    CAS:
    Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.
    Formula:C24H29N3O3
    Purity:99.57%
    Color and Shape:White Solid
    Molecular weight:407.51

    Ref: TM-T32913

  • (Rac)-5-Hydroxymethyl Tolterodine hydrochloride
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    (Rac)-5-Hydroxymethyl Tolterodine hydrochloride

    CAS:
    (Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
    Formula:C22H32ClNO2
    Color and Shape:Solid
    Molecular weight:377.95

    Ref: TM-T40161

  • AC1-IN-1
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    AC1-IN-1

    CAS:
    AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
    Formula:C18H18FN5O2
    Purity:99.89%
    Color and Shape:White Solid
    Molecular weight:355.3662

    Ref: TM-T60003

  • Muscarine
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    Muscarine

    CAS:
    Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.
    Formula:C9H20NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:174.26

    Ref: TM-T24507

  • Rivanicline 2HCl
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    Rivanicline 2HCl

    Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.
    Formula:C10H16Cl2N2
    Purity:99.4%
    Color and Shape:Soild
    Molecular weight:235.15

    Ref: TM-T12738L1

  • TC-2559 difumarate
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    TC-2559 difumarate

    CAS:
    TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.
    Formula:C20H26N2O9
    Color and Shape:Solid
    Molecular weight:438.43

    Ref: TM-T40119

  • α-Bungarotoxin
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    α-Bungarotoxin

    CAS:
    Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).
    Formula:C338H529N97O105S11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:7984.14

    Ref: TM-TP2077

  • (R)-Dinotefuran
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    (R)-Dinotefuran

    CAS:
    (R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.
    Formula:C7H14N4O3
    Color and Shape:Solid
    Molecular weight:202.21

    Ref: TM-T75301

  • CymitQuimica logo
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    M1/M4 muscarinic agonist 1

    M1/M4 muscarinic agonist 1 (Compound 41) is a selective muscarinic M4/M1 agonist with EC50 values of 14 nM for M4 receptors and 55 nM for M1 receptors. This compound is utilized in research related to psychiatric disorders, including schizophrenia and delusional disorders.
    Formula:C23H34N2O2
    Molecular weight:370.26203

    Ref: TM-T208230

  • M4 mAChR agonist-1
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    M4 mAChR agonist-1

    CAS:
    M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).
    Formula:C14H18N4OS
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:290.384

    Ref: TM-T9889

  • G-Protein antagonist peptide
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    G-Protein antagonist peptide

    CAS:
    Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.
    Formula:C57H64N12O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1093.27

    Ref: TM-TP1902

  • trans-Cevimeline hydrochloride
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    trans-Cevimeline hydrochloride

    CAS:
    AF 102A hydrochloride is a biochemical.
    Formula:C10H18ClNOS
    Color and Shape:Solid
    Molecular weight:235.77

    Ref: TM-T29681

  • Atracurium
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    Atracurium

    CAS:
    Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.
    Formula:C53H72N2O122
    Color and Shape:Solid
    Molecular weight:929.14

    Ref: TM-T75283

  • (R)-(+)-Anatabine
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    (R)-(+)-Anatabine

    CAS:
    (R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.
    Formula:C10H12N2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:160.22

    Ref: TM-T12636