AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 574 products of "AChR"
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AC1-IN-1
CAS:<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Formula:C18H18FN5O2Purity:99.89%Color and Shape:SolidMolecular weight:355.37(rel)-Asperparaline A
CAS:<p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>Formula:C20H29N3O3Color and Shape:SolidMolecular weight:359.47Perlapine
CAS:<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Formula:C19H21N3Color and Shape:SolidMolecular weight:291.39TMPH
CAS:<p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>Formula:C16H31NO2Purity:99.78%Color and Shape:SoildMolecular weight:269.428-Aminoadenine
CAS:<p>8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.</p>Formula:C5H6N6Purity:99.82%Color and Shape:SolidMolecular weight:150.14TDI-10229
CAS:<p>TDI-10229: potent oral sAC inhibitor, IC50=195 nM. Good mouse pharmacokinetics for in vivo use.</p>Formula:C16H16ClN5Purity:99.85% - 99.89%Color and Shape:SoildMolecular weight:313.78M3/PDE4 modulator-1
<p>M3/PDE4 Modulator-1 (compound 10f) serves as a bifunctional entity functioning both as an M3 mAChR antagonist and a PDE4 inhibitor.</p>Formula:C38H41Cl2N3O8SColor and Shape:SolidMolecular weight:770.72(R)-Dinotefuran
CAS:<p>(R)-Dinotefuran, a neonicotinoid, is 1.7-2.4x more effective against pests like Aphis gossypii and safer for bees.</p>Formula:C7H14N4O3Color and Shape:SolidMolecular weight:202.21nAChR modulator-1
CAS:<p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Formula:C12H8ClN3O2Color and Shape:SolidMolecular weight:261.66nAChR agonist CMPI hydrochloride
CAS:<p>CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.</p>Formula:C18H20Cl2N4OColor and Shape:SolidMolecular weight:379.29Dicloromezotiaz
CAS:<p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>Formula:C19H12Cl3N3O2SColor and Shape:SolidMolecular weight:452.74Navafenterol
CAS:<p>AZD-8871, a potential COPD and asthma treatment, may work well with ICS.</p>Formula:C38H42N6O6S2Color and Shape:SolidMolecular weight:742.91α-Conotoxin PIA TFA
<p>α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.</p>Formula:C81H126F3N27O27S4Purity:98.81%Color and Shape:SolidMolecular weight:2095.3α-Conotoxin imi
CAS:<p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>Formula:C52H78N20O15S4Purity:98%Color and Shape:SolidMolecular weight:1351.56α-Bungarotoxin
CAS:<p>Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).</p>Formula:C338H529N97O105S11Purity:98%Color and Shape:SolidMolecular weight:7984.14Doxacurium Chloride
CAS:<p>Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.</p>Formula:C56H78ClN2O16Purity:98%Color and Shape:SolidMolecular weight:1070.69G-Protein antagonist peptide
CAS:<p>Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.</p>Formula:C57H64N12O9SPurity:98%Color and Shape:SolidMolecular weight:1093.27Heliosupine N-oxide
<p>Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.</p>Formula:C20H31NO8Color and Shape:SolidMolecular weight:413.467rac-Desethyl Oxybutynin (hydrochloride)
CAS:<p>rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.</p>Formula:C20H28ClNO3Color and Shape:SolidMolecular weight:365.89α-Conotoxin AuIB
CAS:<p>Selective antagonist of α3β4 nicotinic acetylcholine receptors.</p>Formula:C65H89N17O21S4Purity:98%Color and Shape:SolidMolecular weight:1572.76
