PAI-1
Plasminogen Activator Inhibitor-1 (PAI-1) is a serine protease inhibitor that regulates fibrinolysis by inhibiting tissue plasminogen activator (tPA) and urokinase (uPA). Elevated levels of PAI-1 are associated with an increased risk of thrombosis, cardiovascular diseases, and metabolic syndrome. PAI-1 inhibitors are being investigated for their potential to treat these conditions. At CymitQuimica, we offer PAI-1 inhibitors to support your research in hematology, cardiovascular health, and metabolic diseases.
Found 25 products of "PAI-1"
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Upamostat
CAS:<p>Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.</p>Formula:C32H47N5O6SPurity:99.41%Color and Shape:SolidMolecular weight:629.81Angstrom6
CAS:<p>Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade</p>Formula:C39H62N10O15Purity:99.36%Color and Shape:SolidMolecular weight:910.97CT140
<p>CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.</p>Color and Shape:Odour LiquidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formula:C14H26Cl2N6O5Color and Shape:SolidMolecular weight:428.13417Nattokinase
CAS:<p>Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.</p>Color and Shape:SolidUK140
<p>UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.</p>Formula:C72H105N19O25S3Color and Shape:SolidMolecular weight:1732.91Bicyclic UK18
CAS:<p>Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.</p>Formula:C77H118N26O25S3Color and Shape:SolidMolecular weight:1904.11UK-371804
CAS:<p>UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.</p>Formula:C14H16ClN5O4SPurity:95.81% - 99.77%Color and Shape:SolidMolecular weight:385.83Loureirin B
CAS:<p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Formula:C21H17ClN2O6Purity:97.62% - 99.09%Color and Shape:SolidMolecular weight:428.82TM5007
CAS:<p>TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).</p>Formula:C24H20N2O6S4Purity:96.91%Color and Shape:SolidMolecular weight:560.69Tiplaxtinin
CAS:<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Formula:C24H16F3NO4Purity:99.16% - 99.93%Color and Shape:SolidMolecular weight:439.38Toddalolactone
CAS:<p>Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.</p>Formula:C16H20O6Purity:99.06% - 99.85%Color and Shape:SolidMolecular weight:308.33TM5275 sodium
CAS:<p>TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).</p>Formula:C28H27ClN3NaO5Purity:98.8% - 99.74%Color and Shape:SolidMolecular weight:543.98MDI-2268
CAS:<p>MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.</p>Formula:C10H10F3N3O3Color and Shape:SolidMolecular weight:277.20SK-216
CAS:<p>SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.</p>Formula:C29H29NNa2O6Purity:98.29%Color and Shape:SolidMolecular weight:533.52UK-371804 HCl
CAS:<p>UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-</p>Formula:C14H17Cl2N5O4SPurity:98%Color and Shape:SolidMolecular weight:422.29Diaplasinin
CAS:<p>Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.</p>Formula:C32H31N5OPurity:99.02%Color and Shape:SolidMolecular weight:501.62Aleplasinin
CAS:<p>Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic</p>Formula:C28H27NO3Purity:99.21%Color and Shape:SolidMolecular weight:425.52AZ3976
CAS:<p>AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.</p>Formula:C15H19N5O3Purity:98.14%Color and Shape:SolidMolecular weight:317.34
