PAI-1
Plasminogen Activator Inhibitor-1 (PAI-1) is a serine protease inhibitor that regulates fibrinolysis by inhibiting tissue plasminogen activator (tPA) and urokinase (uPA). Elevated levels of PAI-1 are associated with an increased risk of thrombosis, cardiovascular diseases, and metabolic syndrome. PAI-1 inhibitors are being investigated for their potential to treat these conditions. At CymitQuimica, we offer PAI-1 inhibitors to support your research in hematology, cardiovascular health, and metabolic diseases.
Found 26 products of "PAI-1"
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Formula:C32H47N5O6SPurity:99.41%Color and Shape:SolidMolecular weight:629.81Ref: TM-T13257
1mg64.00€2mg94.00€5mg145.00€10mg226.00€25mg379.00€50mg538.00€100mg730.00€1mL*10mM (DMSO)163.00€Angstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFormula:C39H62N10O15Purity:99.36%Color and Shape:SolidMolecular weight:910.97CT140
CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.Color and Shape:Odour LiquidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formula:C14H26Cl2N6O5Color and Shape:SolidMolecular weight:428.13417Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Color and Shape:SolidUK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Formula:C72H105N19O25S3Color and Shape:SolidMolecular weight:1732.91Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Formula:C77H118N26O25S3Color and Shape:SolidMolecular weight:1904.116-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Formula:C6H13NO2Color and Shape:Fine White Crystalline Powder SolidMolecular weight:131.17TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Formula:C21H17ClN2O6Purity:97.62% - 99.09%Color and Shape:SolidMolecular weight:428.82Tiplaxtinin
CAS:<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Formula:C24H16F3NO4Purity:99.16% - 99.93%Color and Shape:SolidMolecular weight:439.38UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Formula:C14H16ClN5O4SPurity:95.81% - 99.77%Color and Shape:SolidMolecular weight:385.83Ref: TM-T3442
1mg52.00€2mg66.00€5mg108.00€10mg180.00€25mg324.00€50mg487.00€100mg705.00€500mg1,473.00€1mL*10mM (DMSO)117.00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purity:99.33% - 99.86%Color and Shape:SolidMolecular weight:316.35TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Formula:C24H20N2O6S4Purity:96.91%Color and Shape:SolidMolecular weight:560.69TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Formula:C28H27ClN3NaO5Purity:98.8% - 99.74%Color and Shape:SolidMolecular weight:543.98Ref: TM-T4255
2mg42.00€5mg65.00€10mg87.00€25mg169.00€50mg245.00€100mg353.00€200mg492.00€1mL*10mM (DMSO)71.00€Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Formula:C16H20O6Purity:99.8% - 99.85%Color and Shape:SolidMolecular weight:308.33Ref: TM-T4S0592
2mg37.00€5mg52.00€10mg73.00€25mg105.00€50mg152.00€100mg215.00€200mg320.00€1mL*10mM (DMSO)63.00€MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Formula:C10H10F3N3O3Color and Shape:SolidMolecular weight:277.20Diaplasinin
CAS:Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.Formula:C32H31N5OPurity:99.02%Color and Shape:SolidMolecular weight:501.62Ref: TM-T25915
1mg60.00€5mg127.00€10mg188.00€25mg432.00€50mg747.00€100mg1,216.00€1mL*10mM (DMSO)140.00€UK-371804 HCl
CAS:UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-Formula:C14H17Cl2N5O4SPurity:98%Color and Shape:SolidMolecular weight:422.29SK-216
CAS:SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.Formula:C29H29NNa2O6Purity:98.29%Color and Shape:SolidMolecular weight:533.52p-Aminobenzamidine dihydrochloride
CAS:4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase typeFormula:C7H11Cl2N3Purity:99.00% - 99.56%Color and Shape:SolidMolecular weight:208.088
