PAI-1

Plasminogen Activator Inhibitor-1 (PAI-1) is a serine protease inhibitor that regulates fibrinolysis by inhibiting tissue plasminogen activator (tPA) and urokinase (uPA). Elevated levels of PAI-1 are associated with an increased risk of thrombosis, cardiovascular diseases, and metabolic syndrome. PAI-1 inhibitors are being investigated for their potential to treat these conditions. At CymitQuimica, we offer PAI-1 inhibitors to support your research in hematology, cardiovascular health, and metabolic diseases.

13 products on this category.

Product data	Purity	Price range	Estimated delivery
Upamostat REF: TM-T13257CAS: 590368-25-5	99.41%	94.00 €~1,189.00 €	Thu 05 Dec 24
Angstrom6 REF: TM-T26629CAS: 220334-14-5	99.36%	53.00 €~1,374.00 €	Tue 10 Dec 24
TM5007 REF: TM-T8962CAS: 342595-05-5	96.91%	143.00 €~991.00 €	Thu 12 Dec 24
TM5441 REF: TM-T4254CAS: 1190221-43-2	97.62% - 99.09%	40.00 €~1,363.00 €	Thu 12 Dec 24
UK-371804 REF: TM-T3442CAS: 256477-09-5	95.81% - 99.26%	52.00 €~1,439.00 €	Thu 12 Dec 24
Loureirin B REF: TM-T3876CAS: 119425-90-0	99.33% - 99.86%	52.00 €~604.00 €	Thu 12 Dec 24
TM5275 sodium REF: TM-T4255CAS: 1103926-82-4	99.02% - 99.55%	41.00 €~1,187.00 €	Thu 12 Dec 24
Toddalolactone REF: TM-T4S0592CAS: 483-90-9	99.06% - 99.85%	65.00 €~97.00 €	Thu 12 Dec 24
Tiplaxtinin REF: TM-T2030CAS: 393105-53-8	98% - 99.49%	44.00 €~1,068.00 €	Thu 12 Dec 24
Aleplasinin REF: TM-T29856CAS: 481629-87-2	97.51%	56.00 €~1,012.00 €	Thu 23 Jan 25
AZ3976 REF: TM-T23764CAS: 1418747-15-5	98.01%	41.00 €~493.00 €	Thu 23 Jan 25
GW-6604 REF: TM-T9947CAS: 452342-37-9	99.26%	35.00 €~397.00 €	Thu 06 Feb 25
ZK824190 REF: TM-T13408CAS: 2254001-81-3	98.84%	256.00 €~2,129.00 €	Thu 06 Feb 25

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Upamostat

CAS:590368-25-5

Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) …

Formula:

C₃₂H₄₇N₅O₆S

Purity:

99.41%

Color and Shape:

Solid

Molecular weight:

629.81

Ref: TM-T13257

1mg		94.00 €
5mg		231.00 €
10mg		369.00 €
25mg		616.00 €
50mg		877.00 €
100mg		1,189.00 €
1mL*10mM (DMSO)		323.00 €

Estimated delivery in United States, on Thursday 5 Dec 2024

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Angstrom6

CAS:220334-14-5

Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen …

Formula:

C₃₉H₆₂N₁₀O₁₅

Purity:

99.36%

Color and Shape:

Solid

Molecular weight:

910.97

Ref: TM-T26629

1mg		53.00 €
5mg		118.00 €
10mg		184.00 €
25mg		323.00 €
50mg		479.00 €
100mg		684.00 €
500mg		1,374.00 €

Estimated delivery in United States, on Tuesday 10 Dec 2024

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TM5007

CAS:342595-05-5

TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).

Formula:

C₂₄H₂₀N₂O₆S₄

Purity:

96.91%

Color and Shape:

Solid

Molecular weight:

560.69

Ref: TM-T8962

1mg		143.00 €
5mg		282.00 €
10mg		424.00 €
25mg		700.00 €
50mg		991.00 €

Estimated delivery in United States, on Thursday 12 Dec 2024

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TM5441

CAS:1190221-43-2

TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines …

Formula:

C₂₁H₁₇ClN₂O₆

Purity:

97.62% - 99.09%

Color and Shape:

Solid

Molecular weight:

428.82

Ref: TM-T4254

1mg		40.00 €
2mg		52.00 €
5mg		85.00 €
10mg		118.00 €
25mg		246.00 €
50mg		461.00 €
100mg		655.00 €
500mg		1,363.00 €

Estimated delivery in United States, on Thursday 12 Dec 2024

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UK-371804

CAS:256477-09-5

UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.

Formula:

C₁₄H₁₆ClN₅O₄S

Purity:

95.81% - 99.26%

Color and Shape:

Solid

Molecular weight:

385.83

Ref: TM-T3442

1mg		52.00 €
2mg		66.00 €
5mg		107.00 €
10mg		178.00 €
25mg		320.00 €
50mg		481.00 €
100mg		697.00 €
500mg		1,439.00 €
1mL*10mM (DMSO)		116.00 €

Estimated delivery in United States, on Thursday 12 Dec 2024

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Loureirin B

CAS:119425-90-0

Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.

Formula:

C₁₈H₂₀O₅

Purity:

99.33% - 99.86%

Color and Shape:

Solid

Molecular weight:

316.35

Ref: TM-T3876

1mg		52.00 €
5mg		118.00 €
10mg		172.00 €
25mg		275.00 €
50mg		419.00 €
100mg		604.00 €
1mL*10mM (DMSO)		130.00 €

Estimated delivery in United States, on Thursday 12 Dec 2024

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TM5275 sodium

CAS:1103926-82-4

TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).

Formula:

C₂₈H₂₇ClN₃NaO₅

Purity:

99.02% - 99.55%

Color and Shape:

Solid

Molecular weight:

543.98

Ref: TM-T4255

2mg		41.00 €
5mg		63.00 €
10mg		95.00 €
25mg		163.00 €
50mg		236.00 €
100mg		340.00 €
200mg		474.00 €
1mL*10mM (DMSO)		69.00 €

Estimated delivery in United States, on Thursday 12 Dec 2024

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Toddalolactone

CAS:483-90-9

Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.

Formula:

C₁₆H₂₀O₆

Purity:

99.06% - 99.85%

Color and Shape:

Solid

Molecular weight:

308.33

Ref: TM-T4S0592

20mg		97.00 €
1mL*10mM (DMSO)		66.00 €

Estimated delivery in United States, on Thursday 12 Dec 2024

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Tiplaxtinin

CAS:393105-53-8

Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with …

Formula:

C₂₄H₁₆F₃NO₄

Purity:

98% - 99.49%

Color and Shape:

Solid

Molecular weight:

439.38

Ref: TM-T2030

2mg		44.00 €
5mg		64.00 €
10mg		94.00 €
25mg		151.00 €
50mg		255.00 €
100mg		503.00 €
500mg		1,068.00 €
1mL*10mM (DMSO)		72.00 €

Estimated delivery in United States, on Thursday 12 Dec 2024

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Aleplasinin

CAS:481629-87-2

Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and …

Formula:

C₂₈H₂₇NO₃

Purity:

97.51%

Color and Shape:

Solid

Molecular weight:

425.52

Ref: TM-T29856

1mg		56.00 €
5mg		119.00 €
10mg		184.00 €
25mg		423.00 €
50mg		640.00 €
100mg		1,012.00 €
1mL*10mM (DMSO)		143.00 €

Estimated delivery in United States, on Thursday 23 Jan 2025

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AZ3976

CAS:1418747-15-5

AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma …

Formula:

C₁₅H₁₉N₅O₃

Purity:

98.01%

Color and Shape:

Solid

Molecular weight:

317.34

Ref: TM-T23764

1mg		41.00 €
5mg		86.00 €
10mg		123.00 €
25mg		223.00 €
50mg		333.00 €
100mg		493.00 €
1mL*10mM (DMSO)		45.00 €

Estimated delivery in United States, on Thursday 23 Jan 2025

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GW-6604

CAS:452342-37-9

GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.

Formula:

C₁₉H₁₄N₄

Purity:

99.26%

Color and Shape:

Liquid

Molecular weight:

298.34

Ref: TM-T9947

1mg		35.00 €
5mg		79.00 €
10mg		114.00 €
25mg		182.00 €
50mg		272.00 €
100mg		397.00 €

Estimated delivery in United States, on Thursday 6 Feb 2025

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ZK824190

CAS:2254001-81-3

ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.

Formula:

C₂₂H₂₀F₂N₂O₄

Purity:

98.84%

Color and Shape:

Solid

Molecular weight:

414.4

Ref: TM-T13408

1mg		256.00 €
5mg		534.00 €
10mg		766.00 €
25mg		1,173.00 €
50mg		1,576.00 €
100mg		2,129.00 €
1mL*10mM (DMSO)		553.00 €

Estimated delivery in United States, on Thursday 6 Feb 2025

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