Glutaminase
Glutaminase inhibitors are compounds that inhibit glutaminase, an enzyme that catalyzes the conversion of glutamine to glutamate, a critical step in cellular metabolism, especially in cancer cells. Glutaminase plays a key role in providing energy and biosynthetic precursors for rapidly proliferating cells. Inhibitors of glutaminase are important for exploring metabolic dependencies in cancer cells and developing potential therapeutic strategies. At CymitQuimica, we provide glutaminase inhibitors to support your research in cancer metabolism, cellular bioenergetics, and therapeutic discovery.
Found 44 products for "Glutaminase".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
JHU-083
CAS:JHU-083 is a glutaminase antagonist that improves cognition and normalizes aberrant hippocampal glutaminase activity in APOE4 mice.Formula:C14H24N4O4Purity:97.89% - 99.53%Color and Shape:SolidMolecular weight:312.37GLS1 Inhibitor
CAS:GLS1 inhibitor blocks glutaminase 1 (IC50=0.021 μM), hinders NCI H1703 NSCLC cell growth in vitro (GI50=0.011 μM), and suppresses tumors in mice.Formula:C19H21N7O2SColor and Shape:SolidMolecular weight:411.48NC9 TG2 inhibitor
CAS:NC9 is an irreversible inhibitor of transglutaminase 2 (TG2) and also inhibits Factor XIIIA (FXIIIA).Formula:C35H47N5O8SPurity:98%Color and Shape:SolidMolecular weight:697.84AA9 TG2 inhibitor
CAS:AA9 is a novel transglutaminase (TG2) inhibitor.Formula:C32H36N4O5Color and Shape:SolidMolecular weight:556.65AA10 TG2 inhibitor
CAS:AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).Formula:C32H36N4O5Color and Shape:SolidMolecular weight:556.65GLS1 Inhibitor-3
CAS:GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.Formula:C30H32N10O2SColor and Shape:SolidMolecular weight:596.71VA4 TG2 inhibitor
CAS:VA4 is a novel irreversible TG2 transamidase site-specific inhibitor.Formula:C33H41N5O6SColor and Shape:SolidMolecular weight:635.77α-Glucosidase-IN-5
CAS:α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM.Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27Glutaminase-IN-4
CAS:Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor (IC50: 2.3 μM).Formula:C23H22N6O2S2Color and Shape:SolidMolecular weight:478.59Duazomycin
CAS:Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.Formula:C8H11N3O4Color and Shape:SolidMolecular weight:213.19CP4d inhibitor
CAS:CP4d is a novel reversible tg2 transamidase site-specific inhibitorFormula:C18H13N5O5Color and Shape:SolidMolecular weight:379.33THDP-17
CAS:THDP-17 is a inhibitor of glutaminase. THDP-17 shows a partial uncompetitive inhibition in vitro.Formula:C12H16N2SPurity:98%Color and Shape:SolidMolecular weight:220.33TG2-IN-3h
CAS:TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitorFormula:C21H26N4O4SPurity:99.34% - 99.76%Color and Shape:SolidMolecular weight:430.52Sirpiglenastat
CAS:Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.Formula:C22H27N5O5Purity:98.01% - 98.37%Color and Shape:SolidMolecular weight:441.48IPN60090
CAS:IPN60090: potent oral GLS1 inhibitor, IC50 of 31 nM, potential for anticancer and immunomodulation.Formula:C24H27F3N8O3Purity:99.76%Color and Shape:SolidMolecular weight:532.52Ref: TM-T11412
1mg100.00€5mg236.00€1mL*10mM (DMSO)268.00€10mg371.00€25mg602.00€50mg893.00€100mg1,189.00€UPGL00004
CAS:UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.Formula:C25H26N8O2S2Purity:97.93%Color and Shape:Red SolidMolecular weight:534.66TG-2-IN-1
CAS:TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].Formula:C8H13ClN2OSPurity:98.43%Color and Shape:White SolidMolecular weight:220.72KCC009
CAS:KCC009 is a TG2 inhibitor; IC50=20 μM; blocks survival signaling; cancer chemotherapy sensitization; glioblastoma research.Formula:C21H22BrN3O5Purity:98.68%Color and Shape:White SolidMolecular weight:476.32ZED-1227
CAS:ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac DiseasFormula:C26H36N6O6Purity:99.04%Color and Shape:SolidMolecular weight:528.6Ref: TM-T17289
1mg235.00€2mg331.00€5mg482.00€1mL*10mM (DMSO)560.00€10mg735.00€25mg1,431.00€50mg2,322.00€TGase2-IN-1
CAS:TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.Formula:C23H25N3O3Color and Shape:SolidMolecular weight:391.46
