CymitQuimica logo
Glutaminase

Glutaminase

Glutaminase inhibitors are compounds that inhibit glutaminase, an enzyme that catalyzes the conversion of glutamine to glutamate, a critical step in cellular metabolism, especially in cancer cells. Glutaminase plays a key role in providing energy and biosynthetic precursors for rapidly proliferating cells. Inhibitors of glutaminase are important for exploring metabolic dependencies in cancer cells and developing potential therapeutic strategies. At CymitQuimica, we provide glutaminase inhibitors to support your research in cancer metabolism, cellular bioenergetics, and therapeutic discovery.

Found 40 products of "Glutaminase"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • GLS1 Inhibitor-3
    Targetmol
    + Info

    GLS1 Inhibitor-3

    CAS:
    <p>GLS1 Inhibitor-3 (compound C147) is a potent inhibitor of GLS1 (IC50: 27.98 nM) and exhibits anti-proliferative effects.</p>
    Formula:C30H32N10O2S
    Color and Shape:Solid
    Molecular weight:596.71

    Ref: TM-T64211

  • α-Glucosidase-IN-5
    Targetmol
    + Info

    α-Glucosidase-IN-5

    CAS:
    <p>α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM.</p>
    Formula:C15H13NO3
    Color and Shape:Solid
    Molecular weight:255.27

    Ref: TM-T60389

  • Glutaminase-IN-4
    Targetmol
    + Info

    Glutaminase-IN-4

    CAS:
    <p>Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor (IC50: 2.3 μM).</p>
    Formula:C23H22N6O2S2
    Color and Shape:Solid
    Molecular weight:478.59

    Ref: TM-T63137

  • AA10 TG2 inhibitor
    Targetmol
    + Info

    AA10 TG2 inhibitor

    CAS:
    <p>AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).</p>
    Formula:C32H36N4O5
    Color and Shape:Solid
    Molecular weight:556.65

    Ref: TM-T26494

  • Duazomycin
    Targetmol
    + Info

    Duazomycin

    CAS:
    <p>Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.</p>
    Formula:C8H11N3O4
    Color and Shape:Solid
    Molecular weight:213.19

    Ref: TM-T27217

  • AA9 TG2 inhibitor
    Targetmol
    + Info

    AA9 TG2 inhibitor

    CAS:
    <p>AA9 is a novel transglutaminase (TG2) inhibitor.</p>
    Formula:C32H36N4O5
    Color and Shape:Solid
    Molecular weight:556.65

    Ref: TM-T69878

  • JHU-083
    Targetmol
    + Info

    JHU-083

    CAS:
    <p>JHU-083 is a glutaminase antagonist that improves cognition and normalizes aberrant hippocampal glutaminase activity in APOE4 mice.</p>
    Formula:C14H24N4O4
    Purity:97.89% - 99.53%
    Color and Shape:Solid
    Molecular weight:312.37

    Ref: TM-T15613

  • GLS1 Inhibitor
    Targetmol
    + Info

    GLS1 Inhibitor

    CAS:
    <p>GLS1 inhibitor blocks glutaminase 1 (IC50=0.021 μM), hinders NCI H1703 NSCLC cell growth in vitro (GI50=0.011 μM), and suppresses tumors in mice.</p>
    Formula:C19H21N7O2S
    Color and Shape:Solid
    Molecular weight:411.48

    Ref: TM-T37222

  • NC9 TG2 inhibitor
    Targetmol
    + Info

    NC9 TG2 inhibitor

    CAS:
    <p>NC9 is an irreversible inhibitor of transglutaminase 2 (TG2) and also inhibits Factor XIIIA (FXIIIA).</p>
    Formula:C35H47N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:697.84

    Ref: TM-T28137

  • IPN60090
    Targetmol
    + Info

    IPN60090

    CAS:
    <p>IPN60090: potent oral GLS1 inhibitor, IC50 of 31 nM, potential for anticancer and immunomodulation.</p>
    Formula:C24H27F3N8O3
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:532.52

    Ref: TM-T11412

  • UPGL00004
    Targetmol
    + Info

    UPGL00004

    CAS:
    <p>UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.</p>
    Formula:C25H26N8O2S2
    Purity:97.93%
    Color and Shape:Solid
    Molecular weight:534.66

    Ref: TM-T17206

  • Sirpiglenastat
    Targetmol
    + Info

    Sirpiglenastat

    CAS:
    <p>Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.</p>
    Formula:C22H27N5O5
    Purity:98.01% - 98.37%
    Color and Shape:Solid
    Molecular weight:441.48

    Ref: TM-T62560

  • TG2-IN-3h
    Targetmol
    + Info

    TG2-IN-3h

    CAS:
    <p>TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitor</p>
    Formula:C21H26N4O4S
    Purity:99.34% - 99.76%
    Color and Shape:Solid
    Molecular weight:430.52

    Ref: TM-T70413

  • TG-2-IN-1
    Targetmol
    + Info

    TG-2-IN-1

    CAS:
    <p>TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].</p>
    Formula:C8H13ClN2OS
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:220.72

    Ref: TM-T60274

  • KCC009
    Targetmol
    + Info

    KCC009

    CAS:
    <p>KCC009 is a potent and selective Transglutaminase 2 Inhibitor.</p>
    Formula:C21H22BrN3O5
    Color and Shape:Solid
    Molecular weight:476.32

    Ref: TM-T27717

  • ZED-1227
    Targetmol
    + Info

    ZED-1227

    CAS:
    <p>ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Diseas</p>
    Formula:C26H36N6O6
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:528.6

    Ref: TM-T17289

  • TG-2-IN-4
    Targetmol
    + Info

    TG-2-IN-4

    CAS:
    <p>TG-2-IN-4 (compound 8), an inhibitor of transglutaminase 2 (TG2) with an IC 50 value of less than 0.5 mM, is utilized in the study of inflammatory disorders [1].</p>
    Formula:C34H40N6O5
    Color and Shape:Solid
    Molecular weight:612.72

    Ref: TM-T87508

  • TGase2-IN-1
    Targetmol
    + Info

    TGase2-IN-1

    CAS:
    <p>TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.</p>
    Formula:C23H25N3O3
    Color and Shape:Solid
    Molecular weight:391.46

    Ref: TM-T201596

  • CymitQuimica logo
    Targetmol
    + Info

    GLS-1-IN-1

    <p>GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.</p>
    Formula:C26H25FN4OS
    Color and Shape:Solid
    Molecular weight:460.57

    Ref: TM-T62905

  • IPN60090 dihydrochloride
    Targetmol
    + Info

    IPN60090 dihydrochloride

    CAS:
    <p>IPN-60090 dihydrochloride is a potent and specific inhibitor of glutaminase 1 (GLS1) with a remarkable inhibition constant (IC50) of 31 nM. It does not exhibit any inhibitory activity against GLS-2. Furthermore, IPN-60090 dihydrochloride possesses outstanding physicochemical properties and pharmacokinetic characteristics in vivo. Therefore, it is a valuable compound for researching solid tumors, including lung and ovarian cancers.</p>
    Formula:C24H29Cl2F3N8O3
    Color and Shape:Solid
    Molecular weight:605.44

    Ref: TM-T39544

    ne
    Discontinued
    Discontinued product