Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
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TNIK-IN-7
CAS:1417795-24-4
TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the …
Formula:
C23H22N4O2
Purity:
99.87%
Color and Shape:
Soild
Molecular weight:
386.45
Ref: TM-T77719
| 1mg | 134.00 € | ||
| 5mg | 322.00 € | ||
| 10mg | 491.00 € | ||
| 25mg | 827.00 € | ||
| 50mg | 1,141.00 € | ||
| 100mg | 1,474.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
F7H
CAS:897109-93-2
F7H is an FZD7 antagonist, a potent ligand for the FZD7 transmembrane domain (TMD), with …
Formula:
C24H18FN3O2S2
Purity:
99.85%
Color and Shape:
Soild
Molecular weight:
463.55
Ref: TM-T77692
| 1mg | 47.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 387.00 € | ||
| 100mg | 551.00 € | ||
| 500mg | 1,178.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
ABC99
CAS:2331255-53-7
ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.
Formula:
C22H21ClN4O5
Purity:
98.65%
Color and Shape:
Soild
Molecular weight:
456.88
Ref: TM-T23602
| 1mg | 168.00 € | ||
| 5mg | 346.00 € | ||
| 10mg | 519.00 € | ||
| 25mg | 836.00 € | ||
| 50mg | 1,132.00 € | ||
| 100mg | 1,531.00 € | ||
| 1mL*10mM (DMSO) | 352.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
IWP-3
CAS:687561-60-0
IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It …
Formula:
C22H17FN4O2S3
Purity:
98.38%
Color and Shape:
Solid
Molecular weight:
484.59
Ref: TM-T21650
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 806.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PRI-724
CAS:1422253-38-0
PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.
Formula:
C33H35N6O7P
Purity:
98.25% - 99.11%
Color and Shape:
Soild
Molecular weight:
658.64
Ref: TM-T64414
| 1mg | 49.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 414.00 € | ||
| 100mg | 614.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BML-284 hydrochloride
CAS:2095432-75-8
BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and …
Formula:
C19H19ClN4O3
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
386.84
Ref: TM-T8820
| 1mg | 35.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 147.00 € | ||
| 50mg | 261.00 € | ||
| 100mg | 455.00 € | ||
| 200mg | 638.00 € | ||
| 500mg | 994.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Cardiogenol C
CAS:671225-39-1
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
Formula:
C13H16N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
260.29
Ref: TM-T2161
| 1mg | 45.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 165.00 € | ||
| 100mg | 228.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Cardiogenol C hydrochloride
CAS:1049741-55-0
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 …
Formula:
C13H17ClN4O2
Purity:
100% - 99.92%
Color and Shape:
Solid
Molecular weight:
296.75
Ref: TM-T8005
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 263.00 € | ||
| 200mg | 377.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
IWR-1
CAS:1127442-82-3
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
Formula:
C25H19N3O3
Purity:
98.46% - 99.82%
Color and Shape:
Solid
Molecular weight:
409.44
Ref: TM-T2651
| 5mg | 54.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 286.00 € | ||
| 100mg | 407.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LF3
CAS:664969-54-4
LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin …
Formula:
C20H24N4O2S2
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
416.56
Ref: TM-T7399
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 246.00 € | ||
| 100mg | 371.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SKL2001
CAS:909089-13-0
SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.
Formula:
C14H14N4O3
Purity:
97.90% - 99.5%
Color and Shape:
Solid
Molecular weight:
286.29
Ref: TM-T6989
| 5mg | 40.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 183.00 € | ||
| 100mg | 332.00 € | ||
| 200mg | 499.00 € | ||
| 500mg | 784.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
CAS:883715-23-9
Macamide Impurity 14 promotes bone growth by activating Wnt/β-catenin, aiding osteoporosis study.
Formula:
C26H39NO2
Purity:
98.66%
Color and Shape:
Solid
Molecular weight:
397.59
Ref: TM-TN7036
| 1mg | 50.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Adavivint
CAS:1467093-03-3
Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.
Formula:
C29H24FN7O
Purity:
98.27% - ≥98%
Color and Shape:
Solid
Molecular weight:
505.55
Ref: TM-T5636
| 1mg | 47.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 193.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KY-05009
CAS:1228280-29-2
KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and …
Formula:
C18H16N4O2S
Purity:
98.06%
Color and Shape:
Solid
Molecular weight:
352.41
Ref: TM-T11793
| 5mg | 50.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 236.00 € | ||
| 200mg | 342.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Wnt-C59
CAS:1243243-89-1
Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.
Formula:
C25H21N3O
Purity:
99.56% - 99.91%
Color and Shape:
Solid
Molecular weight:
379.45
Ref: TM-T2242
| 2mg | 39.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 196.00 € | ||
| 100mg | 337.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Teplinovivint
CAS:1428064-91-8
Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential …
Formula:
C25H26N6O2
Purity:
97.21%
Color and Shape:
Solid
Molecular weight:
442.51
Ref: TM-T9151
| 1mg | 69.00 € | ||
| 5mg | 136.00 € | ||
| 10mg | 211.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 490.00 € | ||
| 100mg | 676.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
iCRT 14
CAS:677331-12-3
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays …
Formula:
C21H17N3O2S
Purity:
98.85% - 99.8%
Color and Shape:
Solid
Molecular weight:
375.44
Ref: TM-T4486
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 345.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BML-284
CAS:853220-52-7
BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.
Formula:
C19H18N4O3
Purity:
99.66% - 99.91%
Color and Shape:
Solid
Molecular weight:
350.37
Ref: TM-T3144
| 5mg | 59.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 248.00 € | ||
| 100mg | 420.00 € | ||
| 200mg | 602.00 € | ||
| 500mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KY02111
CAS:1118807-13-8
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of …
Formula:
C18H17ClN2O3S
Purity:
97.71%（96.56%） - 98.68%
Color and Shape:
Solid
Molecular weight:
376.86
Ref: TM-T2052
| 10mg | 41.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 136.00 € | ||
| 100mg | 197.00 € | ||
| 200mg | 291.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Windorphen
CAS:19881-70-0
Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.
Formula:
C17H15ClO3
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
302.75
Ref: TM-T7830
| 5mg | 47.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 152.00 € | ||
| 100mg | 212.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
