Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
Found 65 products for "Wnt/beta-catenin".
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Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formula:C28H36N4O6S2Purity:98.47% - 99.95%Color and Shape:SolidMolecular weight:588.74Ref: TM-T5642
1mg38.00€2mg50.00€5mg80.00€1mL*10mM (DMSO)92.00€10mg117.00€25mg198.00€50mg316.00€100mg535.00€Fz7-21
CAS:Fz7-21, a peptide antagonist of FZD7, inhibits Wnt/β-catenin signaling (IC50=50-100nM) in cells with WNT3A.Formula:C83H114N18O23S2Purity:99.8%Color and Shape:White SolidMolecular weight:1796.03KYA1797K
CAS:KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.Formula:C17H11N2O6S2·KPurity:97.57% - 99.33%Color and Shape:SolidMolecular weight:442.51Ref: TM-T6868
2mg39.00€5mg56.00€1mL*10mM (DMSO)62.00€10mg92.00€25mg178.00€50mg301.00€100mg485.00€200mg690.00€IQ 1
CAS:IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.Formula:C21H22N4O2Purity:98.57% - ≥95%Color and Shape:Orange SolidMolecular weight:362.42Ref: TM-T3635
5mg49.00€1mL*10mM (DMSO)54.00€10mg73.00€25mg133.00€50mg185.00€100mg333.00€200mg474.00€500mg767.00€BML-284 hydrochloride
CAS:BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.Formula:C19H19ClN4O3Purity:99.80%Color and Shape:SolidMolecular weight:386.84Ref: TM-T8820
1mg34.00€5mg64.00€10mg84.00€1mL*10mM (DMSO)94.00€25mg142.00€50mg253.00€100mg439.00€200mg615.00€500mg964.00€WAY-262611
CAS:WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.Formula:C20H22N4Purity:98.09% - 99.09%Color and Shape:SolidMolecular weight:318.42MSAB
CAS:MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.Formula:C15H15NO4SPurity:99.76%Color and Shape:SolidMolecular weight:305.35Ref: TM-T8710
1mg34.00€2mg47.00€5mg70.00€1mL*10mM (DMSO)78.00€10mg113.00€25mg222.00€50mg334.00€100mg507.00€500mg1,063.00€IWP-4
CAS:IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.Formula:C23H20N4O3S3Purity:98% - 99.59%Color and Shape:Yellow SolidMolecular weight:496.62PRI-724
CAS:PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.Formula:C33H35N6O7PPurity:98.25% - 98.38%Color and Shape:White SolidMolecular weight:658.64Setrusumab
CAS:Setrusumab (BPS 804) is a fully humanized monoclonal antibody targeting sclerostin, effectively enhancing bone strength.Purity:95% - >95% (SDS-PAGE); 97.8% (SEC-HPLC)Color and Shape:Liquidβ-catenin/CBP-IN-1
CAS:β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-cateninFormula:C33H35N6O7PPurity:98%Color and Shape:SolidMolecular weight:658.64ZW4864 free base
CAS:ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.Formula:C33H42N6O3Purity:99.81%Color and Shape:SolidMolecular weight:570.72Ref: TM-T9642
1mg152.00€5mg371.00€1mL*10mM (DMSO)409.00€10mg557.00€25mg887.00€50mg1,198.00€100mg1,611.00€500mg3,232.00€TNIK-IN-1
CAS:TNIK-IN-1 is a potent TNIK inhibitor (IC50 = 65 nM). It exerts antitumor effects by disrupting the Wnt signaling pathway, utilized in research for colorectal cancer and cancer stemness mechanisms.Formula:C19H17N5O3SPurity:99.01%Color and Shape:SolidMolecular weight:395.43FJ9
CAS:FJ9 is an FZD7 inhibitor that disrupts the protein interaction between Frz7 and the DVL PDZ domain and induces apoptosis in melanoma and non-small cell lung cancer cell lines.Formula:C23H27NO3Purity:99.41% - 99.60%Color and Shape:White SolidMolecular weight:365.47Wnt pathway activator 2
CAS:Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.Formula:C17H15NO4Purity:99.41%Color and Shape:White SolidMolecular weight:297.31GB1874
CAS:GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.Formula:C24H27N3O2SColor and Shape:Yellow SolidMolecular weight:421.56TNKS-IN-1
CAS:TNKS-IN-1 is a highly potent and selective inhibitor of tankyrase.Formula:C18H18N2OPurity:99.98%Color and Shape:SolidMolecular weight:278.35Wnt/β-catenin agonist 4
CAS:Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.Formula:C16H15FN4O2Purity:99.96%Color and Shape:SolidMolecular weight:314.31Ref: TM-T60803
1mg34.00€5mg66.00€1mL*10mM (DMSO)77.00€10mg98.00€25mg172.00€50mg295.00€100mg485.00€200mg682.00€FzM1.8
CAS:FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.Formula:C18H14N2O4Purity:99.89%Color and Shape:SolidMolecular weight:322.31Ref: TM-T15363
2mg38.00€5mg55.00€1mL*10mM (DMSO)60.00€10mg87.00€25mg165.00€50mg264.00€100mg411.00€200mg593.00€FzM1
CAS:FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)Formula:C21H16N2O2SPurity:99.37% - 99.89%Color and Shape:Yellow SolidMolecular weight:360.43Ref: TM-T24076
1mg39.00€1mL*10mM (DMSO)58.00€5mg60.00€10mg94.00€25mg178.00€50mg310.00€100mg500.00€500mg1,071.00€
