Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
Found 66 products of "Wnt/beta-catenin"
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Wnt pathway activator 1
CAS:<p>Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.</p>Formula:C18H16O4Purity:99.93%Color and Shape:SolidMolecular weight:296.32IQ 1
CAS:<p>IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.</p>Formula:C21H22N4O2Purity:98.57% - ≥95%Color and Shape:SolidMolecular weight:362.42WAY 316606
CAS:<p>WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt.</p>Formula:C18H19F3N2O4S2Purity:99.65%Color and Shape:SolidMolecular weight:448.48IWP-O1
CAS:<p>IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.</p>Formula:C26H20N6OPurity:99.12%Color and Shape:SolidMolecular weight:432.48Tegatrabetan
CAS:<p>Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.</p>Formula:C28H36N4O6S2Purity:98.01% - 99.18%Color and Shape:SolidMolecular weight:588.74KYA1797K
CAS:<p>KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.</p>Formula:C17H11N2O6S2·KPurity:97.57% - 99.33%Color and Shape:SolidMolecular weight:442.51Pyrvinium pamoate
CAS:<p>Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug</p>Formula:C26H28N3C23H14O6Purity:99.76% - >99.99%Color and Shape:SolidMolecular weight:575.71ETC-159
CAS:<p>ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM.</p>Formula:C19H17N7O3Purity:96.87% - 99.30%Color and Shape:SolidMolecular weight:391.38BML-284 hydrochloride
CAS:<p>BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.</p>Formula:C19H19ClN4O3Purity:99.80%Color and Shape:SolidMolecular weight:386.84WAY-262611
CAS:<p>WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.</p>Formula:C20H22N4Purity:98.09% - 99.09%Color and Shape:SolidMolecular weight:318.42MSAB
CAS:<p>MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.</p>Formula:C15H15NO4SPurity:99.76%Color and Shape:SolidMolecular weight:305.35IWP-4
CAS:<p>IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.</p>Formula:C23H20N4O3S3Purity:98% - 99.59%Color and Shape:SolidMolecular weight:496.62PRI-724
CAS:<p>PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.</p>Formula:C33H35N6O7PPurity:98.25% - 99.11%Color and Shape:SoildMolecular weight:658.64Wnt pathway activator 2
CAS:<p>Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.</p>Formula:C17H15NO4Purity:99.41%Color and Shape:SolidMolecular weight:297.31ZW4864 free base
CAS:<p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>Formula:C33H42N6O3Purity:99.81%Color and Shape:SolidMolecular weight:570.72β-catenin/CBP-IN-1
CAS:<p>β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-catenin</p>Formula:C33H35N6O7PPurity:98%Color and Shape:SolidMolecular weight:658.64GB1874
CAS:<p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>Formula:C24H27N3O2SColor and Shape:SolidMolecular weight:421.56Wnt/β-catenin agonist 4
CAS:<p>Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.</p>Formula:C16H15FN4O2Purity:99.61%Color and Shape:SolidMolecular weight:314.31FzM1
CAS:<p>FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)</p>Formula:C21H16N2O2SPurity:99.37% - 99.89%Color and Shape:SolidMolecular weight:360.43FzM1.8
CAS:<p>FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.</p>Formula:C18H14N2O4Purity:99.89%Color and Shape:SolidMolecular weight:322.31
