Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
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β-catenin-IN-2
CAS:1458664-10-2
β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.
Formula:
C15H14FN3
Purity:
98.78%
Color and Shape:
Solid
Molecular weight:
255.29
Ref: TM-T9696
| 1mg | 94.00 € | ||
| 5mg | 223.00 € | ||
| 10mg | 352.00 € | ||
| 25mg | 593.00 € | ||
| 50mg | 851.00 € | ||
| 100mg | 1,142.00 € | ||
| 500mg | 2,321.00 € | ||
| 1mL*10mM (DMSO) | 263.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
exo-IWR-1
CAS:1127442-87-8
exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. …
Formula:
C25H19N3O3
Purity:
97.41%
Color and Shape:
Solid
Molecular weight:
409.44
Ref: TM-T22775
| 5mg | 34.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 168.00 € | ||
| 100mg | 269.00 € | ||
| 200mg | 392.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Wnt pathway activator 1
CAS:1360540-81-3
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.
Formula:
C18H16O4
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
296.32
Ref: TM-T17256
| 2mg | 34.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 204.00 € | ||
| 100mg | 305.00 € | ||
| 200mg | 438.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
FH535
CAS:108409-83-2
FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.
Formula:
C13H10Cl2N2O4S
Purity:
98.25% - 99.5%
Color and Shape:
Solid
Molecular weight:
361.2
Ref: TM-T2413
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 161.00 € | ||
| 100mg | 270.00 € | ||
| 200mg | 397.00 € | ||
| 500mg | 642.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
WAY 316606
CAS:915759-45-4
WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the …
Formula:
C18H19F3N2O4S2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
448.48
Ref: TM-T4468
| 5mg | 50.00 € | ||
| 10mg | 76.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 199.00 € | ||
| 100mg | 321.00 € | ||
| 200mg | 459.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
IWP-O1
CAS:2074607-48-8
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation …
Formula:
C26H20N6O
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
432.48
Ref: TM-T5342
| 2mg | 38.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 98.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 309.00 € | ||
| 200mg | 443.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tegatrabetan
CAS:1227637-23-1
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
Formula:
C28H36N4O6S2
Purity:
98.01% - 99.18%
Color and Shape:
Solid
Molecular weight:
588.74
Ref: TM-T5642
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 205.00 € | ||
| 50mg | 327.00 € | ||
| 100mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TNIK-IN-2
CAS:2754265-76-2
TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which …
Formula:
C22H19N3O3
Purity:
98.09%
Color and Shape:
Solid
Molecular weight:
373.4
Ref: TM-T9557
| 1mg | 95.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 276.00 € | ||
| 25mg | 440.00 € | ||
| 50mg | 627.00 € | ||
| 100mg | 843.00 € | ||
| 1mL*10mM (DMSO) | 201.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KYA1797K
CAS:1956356-56-1
KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash …
Formula:
C17H11N2O6S2·K
Purity:
99.33% - ≥95%
Color and Shape:
Solid
Molecular weight:
442.51
Ref: TM-T6868
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 239.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 602.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Pyrvinium pamoate
CAS:3546-41-6
Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , …
Formula:
C26H28N3C23H14O6
Purity:
100% - 98.43%
Color and Shape:
Solid
Molecular weight:
575.71
Ref: TM-T7333
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 116.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ETC-159
CAS:1638250-96-0
ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with …
Formula:
C19H17N7O3
Purity:
96.87% - 99.4%
Color and Shape:
Solid
Molecular weight:
391.38
Ref: TM-T4043
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 345.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
IQ 1
CAS:331001-62-8
IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated …
Formula:
C21H22N4O2
Purity:
98.57% - ≥95%
Color and Shape:
Solid
Molecular weight:
362.42
Ref: TM-T3635
| 5mg | 51.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 345.00 € | ||
| 200mg | 489.00 € | ||
| 500mg | 792.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
WAY-262611
CAS:1123231-07-1
WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate …
Formula:
C20H22N4
Purity:
98.09% - 99.09%
Color and Shape:
Solid
Molecular weight:
318.42
Ref: TM-T1971
| 5mg | 63.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 308.00 € | ||
| 100mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MSAB
CAS:173436-66-3
MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.
Formula:
C15H15NO4S
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
305.35
Ref: TM-T8710
| 1mg | 37.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 523.00 € | ||
| 500mg | 1,099.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Pamidronic acid
CAS:40391-99-9
Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow …
Formula:
C3H11NO7P2
Purity:
97.72%
Color and Shape:
Solid
Molecular weight:
235.07
Ref: TM-T8400
| 25mg | 40.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 87.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
IWP-4
CAS:686772-17-8
IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.
Formula:
C23H20N4O3S3
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
496.62
Ref: TM-T4245
| 1mg | 49.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 325.00 € | ||
| 50mg | 482.00 € | ||
| 100mg | 699.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Miclxin
CAS:2494198-61-5
Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant …
Formula:
C26H27N5O2
Purity:
100% - 99.57%
Color and Shape:
Liquid
Molecular weight:
441.52
Ref: TM-T73415
| 1mg | 93.00 € | ||
| 5mg | 224.00 € | ||
| 10mg | 313.00 € | ||
| 25mg | 528.00 € | ||
| 50mg | 735.00 € | ||
| 100mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 244.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
EMT inhibitor-1
CAS:1638526-21-2
EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor …
Formula:
C12H12Cl2N2O2S
Purity:
99%
Color and Shape:
Solid
Molecular weight:
319.21
Ref: TM-T11190
| 1mg | 107.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 408.00 € | ||
| 25mg | 697.00 € | ||
| 50mg | 969.00 € | ||
| 100mg | 1,326.00 € | ||
| 500mg | 2,633.00 € | ||
| 1mL*10mM (DMSO) | 272.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
DK419
CAS:2102672-22-8
DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.
Formula:
C16H8ClF6N3O
Purity:
98.15%
Color and Shape:
Solid
Molecular weight:
407.7
Ref: TM-T15137
| 1mg | 85.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 254.00 € | ||
| 25mg | 419.00 € | ||
| 50mg | 591.00 € | ||
| 100mg | 797.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
FzM1
CAS:1680196-54-6
FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive …
Formula:
C21H16N2O2S
Purity:
99.37% - 99.89%
Color and Shape:
Solid
Molecular weight:
360.43
Ref: TM-T24076
| 1mg | 41.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 522.00 € | ||
| 500mg | 1,104.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
