Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
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CCT251545
CAS:1661839-45-7
CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).
Formula:
C23H24ClN5O
Purity:
98.2% - 98.69%
Color and Shape:
Solid
Molecular weight:
421.92
Ref: TM-T14907
| 1mg | 42.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 655.00 € |
Estimated delivery in United States, on Tuesday 8 Apr 2025
KY1220
CAS:292168-79-7
KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 …
Formula:
C14H10N4O3S
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
314.32
Ref: TM-T15677
| 2mg | 46.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 117.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 374.00 € | ||
| 100mg | 545.00 € | ||
| 200mg | 740.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 8 Apr 2025
CWP232228
CAS:1144044-02-9
CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and …
Formula:
C33H34N7Na2O7P
Purity:
96.13%
Color and Shape:
Solid
Molecular weight:
717.63
Ref: TM-T10904
| 1mg | 138.00 € | ||
| 5mg | 284.00 € | ||
| 10mg | 411.00 € | ||
| 25mg | 645.00 € | ||
| 50mg | 867.00 € | ||
| 100mg | 1,121.00 € |
Estimated delivery in United States, on Tuesday 8 Apr 2025
JW74
CAS:863405-60-1
JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).
Formula:
C24H20N6O2S
Purity:
95.00%
Color and Shape:
Solid
Molecular weight:
456.52
Ref: TM-T15633
| 5mg | 40.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 145.00 € | ||
| 100mg | 197.00 € | ||
| 200mg | 283.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Tuesday 8 Apr 2025
HLY78
CAS:854847-61-3
HLY78, a Wnt/β-catenin activator, enhances Axin-LRP6 binding by targeting Axin's DIX domain.
Formula:
C17H17NO2
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
267.32
Ref: TM-T11571
| 1mg | 40.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 243.00 € | ||
| 50mg | 390.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 8 Apr 2025
Nefopam hydrochloride
CAS:23327-57-3
Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine …
Formula:
C17H20ClNO
Purity:
99.32% - 99.85%
Color and Shape:
Solid
Molecular weight:
289.8
Ref: TM-T0470
| 1g | 64.00 € | ||
| 500mg | 44.00 € |
Estimated delivery in United States, on Tuesday 8 Apr 2025
SRI 37892
CAS:1030769-75-5
SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell …
Formula:
C26H19N5O2S
Purity:
98.92%
Color and Shape:
Liquid
Molecular weight:
465.53
Ref: TM-T9662
| 1mg | 378.00 € | ||
| 5mg | 922.00 € | ||
| 10mg | 1,225.00 € | ||
| 25mg | 1,853.00 € | ||
| 50mg | 2,490.00 € | ||
| 100mg | 3,353.00 € | ||
| 1mL*10mM (DMSO) | 1,074.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
Ipafricept
CAS:1391727-24-4
Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.
Color and Shape:
Liquid
Ref: TM-T77039
| 1mg | 487.00 € | ||
| 5mg | 1,264.00 € | ||
| 10mg | 2,023.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
Romosozumab
CAS:909395-70-6
Romosozumab (AMG-785) is a humanized monoclonal antibody that binds and inhibits sclerostin, which increases bone …
Purity:
95% - 95%
Color and Shape:
Liquid
Ref: TM-T77380
| 1mg | 239.00 € | ||
| 5mg | 588.00 € | ||
| 10mg | 941.00 € | ||
| 25mg | 1,600.00 € | ||
| 50mg | 2,323.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
TNIK-IN-5
CAS:2754265-66-0
TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.
Formula:
C22H17N3O3
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
371.39
Ref: TM-T9810
| 1mg | 127.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 455.00 € | ||
| 25mg | 777.00 € | ||
| 50mg | 1,074.00 € | ||
| 100mg | 1,454.00 € | ||
| 500mg | 2,822.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
β-catenin modulator IIa-661
CAS:1015859-04-7
β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.
Formula:
C19H23ClN2O3S
Purity:
99.53%
Color and Shape:
Soild
Molecular weight:
394.92
Ref: TM-T67884
| 1mg | 35.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 399.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
TINK-IN-1
CAS:1417795-25-5
TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell …
Formula:
C24H24N4O3
Purity:
99.4%
Color and Shape:
Soild
Molecular weight:
416.47
Ref: TM-T77660
| 1mg | 42.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 547.00 € | ||
| 500mg | 1,159.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
Carboxylesterase-IN-2
CAS:2764748-88-9
Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the …
Formula:
C13H12N4OS
Purity:
100%
Color and Shape:
Soild
Molecular weight:
272.33
Ref: TM-T77524
| 1mg | 62.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 215.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 509.00 € | ||
| 100mg | 702.00 € | ||
| 200mg | 944.00 € | ||
| 1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
Wnt pathway inhibitor 3
CAS:663213-98-7
Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 …
Formula:
C21H17BrN2O5
Purity:
99.69%
Color and Shape:
Soild
Molecular weight:
457.27
Ref: TM-T77502
| 10mg | 39.00 € | ||
| 25mg | 60.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 117.00 € | ||
| 200mg | 172.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
CCT 031374 hydrobromide
CAS:1219184-91-4
CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.
Formula:
C23H20BrN3O
Purity:
98.61%
Color and Shape:
Solid
Molecular weight:
434.33
Ref: TM-T21685
| 1mg | 38.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 329.00 € | ||
| 100mg | 472.00 € | ||
| 200mg | 620.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
Wnt/β-catenin agonist 3
CAS:912790-59-1
Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.
Formula:
C16H15ClN4O2
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
330.77
Ref: TM-T9988
| 5mg | 74.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 567.00 € | ||
| 200mg | 800.00 € | ||
| 500mg | 1,198.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
ABC99
CAS:2331255-53-7
ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.
Formula:
C22H21ClN4O5
Purity:
98.65%
Color and Shape:
Soild
Molecular weight:
456.88
Ref: TM-T23602
| 1mg | 172.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 528.00 € | ||
| 25mg | 852.00 € | ||
| 50mg | 1,159.00 € | ||
| 100mg | 1,568.00 € | ||
| 1mL*10mM (DMSO) | 354.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
TNKS-2-IN-2
CAS:2719726-91-5
TNKS-2-IN-2 is a TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the …
Formula:
C26H23N3O6
Purity:
99.45%
Color and Shape:
Soild
Molecular weight:
473.48
Ref: TM-T77733
| 1mg | 156.00 € | ||
| 5mg | 376.00 € | ||
| 10mg | 533.00 € | ||
| 25mg | 847.00 € | ||
| 50mg | 1,159.00 € | ||
| 100mg | 1,568.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
Vantictumab
CAS:1345009-45-1
Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.
Color and Shape:
Liquid
Ref: TM-T77450
| 1mg | 235.00 € | ||
| 5mg | 612.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,454.00 € | ||
| 50mg | 1,882.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
WIC1
CAS:943083-58-7
2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.
Formula:
C22H23N3O3
Purity:
99.57%
Color and Shape:
Soild
Molecular weight:
377.44
Ref: TM-T67923
| 10mg | 50.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 145.00 € | ||
| 100mg | 226.00 € | ||
| 200mg | 335.00 € |
Estimated delivery in United States, on Wednesday 9 Apr 2025
