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Wnt/beta-catenin

Wnt/beta-catenin

Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.

Found 66 products of "Wnt/beta-catenin"

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  • CCT251545
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    CCT251545

    CAS:
    <p>CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).</p>
    Formula:C23H24ClN5O
    Purity:98.2% - 98.69%
    Color and Shape:Solid
    Molecular weight:421.92

    Ref: TM-T14907

  • TNIK-IN-5
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    TNIK-IN-5

    CAS:
    <p>TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.</p>
    Formula:C22H17N3O3
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:371.39

    Ref: TM-T9810

  • JW74
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    JW74

    CAS:
    <p>JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).</p>
    Formula:C24H20N6O2S
    Purity:95.00%
    Color and Shape:Solid
    Molecular weight:456.52

    Ref: TM-T15633

  • BML-286
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    BML-286

    CAS:
    <p>BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.</p>
    Formula:C22H18N2O4
    Purity:98.44%
    Color and Shape:Solid
    Molecular weight:374.39

    Ref: TM-T200419

  • Nefopam hydrochloride
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    Nefopam hydrochloride

    CAS:
    <p>Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.</p>
    Formula:C17H20ClNO
    Purity:99.32% - 99.85%
    Color and Shape:Solid
    Molecular weight:289.8

    Ref: TM-T0470

  • KY1220
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    KY1220

    CAS:
    <p>KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.</p>
    Formula:C14H10N4O3S
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:314.32

    Ref: TM-T15677

  • CWP232228
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    CWP232228

    CAS:
    <p>CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.</p>
    Formula:C33H34N7Na2O7P
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:717.63

    Ref: TM-T10904

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    Vantictumab

    CAS:
    <p>Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.</p>
    Purity:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)
    Color and Shape:Liquid

    Ref: TM-T77450

  • CymitQuimica logo
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    Romosozumab

    CAS:
    <p>Romosozumab (AMG-785) is a humanized monoclonal antibody that binds and inhibits sclerostin, which increases bone formation and decreases bone resorption.</p>
    Purity:98.9% (SDS-PAGE); 98.2% (SEC-HPLC) - 98.9% (SDS-PAGE); 98.2% (SEC-HPLC)
    Color and Shape:Liquid

    Ref: TM-T77380

  • Wnt pathway inhibitor 3
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    Wnt pathway inhibitor 3

    CAS:
    <p>Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studies</p>
    Formula:C21H17BrN2O5
    Purity:99.69%
    Color and Shape:Soild
    Molecular weight:457.27

    Ref: TM-T77502

  • ABC99
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    ABC99

    CAS:
    <p>ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.</p>
    Formula:C22H21ClN4O5
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:456.88

    Ref: TM-T23602

  • CymitQuimica logo
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    NLS-StAx-h

    <p>Wnt inhibitor; halts cancer cell growth &amp; spread by blocking β-catenin, IC50=1.4μM, cell-permeable.</p>
    Formula:C161H275N55O29
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3445.26

    Ref: TM-TP1979

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    Tabituximab

    CAS:
    <p>BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.</p>
    Purity:98.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 98.7% (SDS-PAGE); 96.4% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:145.5 kDa

    Ref: TM-T77449

  • Carboxylesterase-IN-2
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    Carboxylesterase-IN-2

    CAS:
    <p>Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 &lt;= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.</p>
    Formula:C13H12N4OS
    Purity:99.92%
    Color and Shape:Soild
    Molecular weight:272.33

    Ref: TM-T77524

  • 1(R),2(S)-epoxy Cannabidiol
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    1(R),2(S)-epoxy Cannabidiol

    CAS:
    <p>1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.</p>
    Formula:C21H30O3
    Color and Shape:Solid
    Molecular weight:330.46

    Ref: TM-T203031

  • Foxy-5
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    Foxy-5

    CAS:
    <p>Foxy-5 is a wnt5a peptide mimetic</p>
    Formula:C26H42N6O12S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:694.77

    Ref: TM-TP1565

  • CymitQuimica logo
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    Ipafricept

    CAS:
    <p>Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.</p>
    Purity:99.2% (SDS-PAGE); 97.4% (SEC-HPLC) - 99.2% (SDS-PAGE); 97.4% (SEC-HPLC)
    Color and Shape:Liquid

    Ref: TM-T77039

  • YW2036
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    YW2036

    CAS:
    <p>YW2036 is an inhibitor of Wnt signaling pathway.</p>
    Formula:C20H16N4O
    Purity:99.94%
    Color and Shape:Soild
    Molecular weight:328.37

    Ref: TM-T67866

  • Wnt/β-catenin agonist 3
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    Wnt/β-catenin agonist 3

    CAS:
    <p>Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.</p>
    Formula:C16H15ClN4O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:330.77

    Ref: TM-T9988

  • WIC1
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    WIC1

    CAS:
    <p>2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.</p>
    Formula:C22H23N3O3
    Purity:99.82%
    Color and Shape:Soild
    Molecular weight:377.44

    Ref: TM-T67923