Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
Found 63 products of "Wnt/beta-catenin"
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JW74
CAS:JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formula:C24H20N6O2SPurity:95.00%Color and Shape:SolidMolecular weight:456.52Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formula:C17H20ClNOPurity:99.32% - 99.85%Color and Shape:SolidMolecular weight:289.8Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Purity:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Color and Shape:LiquidTNIK-IN-5
CAS:TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.Formula:C22H17N3O3Purity:99.58%Color and Shape:SolidMolecular weight:371.39CCT251545
CAS:<p>CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).</p>Formula:C23H24ClN5OPurity:98.2% - 98.69%Color and Shape:SolidMolecular weight:421.92KY1220
CAS:<p>KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.</p>Formula:C14H10N4O3SPurity:99.9%Color and Shape:SolidMolecular weight:314.32CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formula:C33H34N7Na2O7PPurity:98.87%Color and Shape:SolidMolecular weight:717.63BML-286
CAS:<p>BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.</p>Formula:C22H18N2O4Purity:98.44%Color and Shape:SolidMolecular weight:374.39Romosozumab
CAS:<p>Romosozumab (AMG-785) is a humanized monoclonal antibody that binds and inhibits sclerostin, which increases bone formation and decreases bone resorption.</p>Purity:98.9% (SDS-PAGE); 98.2% (SEC-HPLC) - 98.9% (SDS-PAGE); 98.2% (SEC-HPLC)Color and Shape:LiquidYW2036
CAS:YW2036 is an inhibitor of Wnt signaling pathway.Formula:C20H16N4OPurity:99.94%Color and Shape:SoildMolecular weight:328.37LP-922056
CAS:<p>LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.</p>Formula:C11H9ClN2O2S2Purity:99.84%Color and Shape:SolidMolecular weight:300.78Wnt/β-catenin agonist 3
CAS:<p>Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.</p>Formula:C16H15ClN4O2Purity:99.52%Color and Shape:SolidMolecular weight:330.77ABC99
CAS:ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.Formula:C22H21ClN4O5Purity:99.89%Color and Shape:SoildMolecular weight:456.88NLS-StAx-h
Wnt inhibitor; halts cancer cell growth & spread by blocking β-catenin, IC50=1.4μM, cell-permeable.Formula:C161H275N55O29Purity:98%Color and Shape:SolidMolecular weight:3445.26Ipafricept
CAS:Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.Purity:99.2% (SDS-PAGE); 97.4% (SEC-HPLC) - 99.2% (SDS-PAGE); 97.4% (SEC-HPLC)Color and Shape:Liquid1(R),2(S)-epoxy Cannabidiol
CAS:<p>1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.</p>Formula:C21H30O3Color and Shape:SolidMolecular weight:330.46Tabituximab
CAS:BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.Purity:98.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 98.7% (SDS-PAGE); 96.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5 kDaFoxy-5
CAS:Foxy-5 is a wnt5a peptide mimeticFormula:C26H42N6O12S2Purity:98%Color and Shape:SolidMolecular weight:694.77Wnt pathway inhibitor 3
CAS:Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studiesFormula:C21H17BrN2O5Purity:99.94%Color and Shape:SoildMolecular weight:457.27WIC1
CAS:<p>2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.</p>Formula:C22H23N3O3Purity:99.82%Color and Shape:SoildMolecular weight:377.44
