Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
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ZW4864 free base
CAS:2632259-92-6
ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein …
Formula:
C33H42N6O3
Purity:
99.54%
Color and Shape:
Solid
Molecular weight:
570.72
Ref: TM-T9642
| 1mg | 157.00 € | ||
| 5mg | 384.00 € | ||
| 10mg | 574.00 € | ||
| 25mg | 915.00 € | ||
| 50mg | 1,240.00 € | ||
| 100mg | 1,663.00 € | ||
| 500mg | 3,331.00 € | ||
| 1mL*10mM (DMSO) | 428.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Tankyrase-IN-2
CAS:1588870-36-3
Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, …
Formula:
C17H14F2N2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
316.3
Ref: TM-T13078
| 25mg | 1,299.00 € | ||
| 50mg | 1,723.00 € | ||
| 100mg | 2,367.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
FzM1.8
CAS:2204290-85-5
FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.
Formula:
C18H14N2O4
Purity:
100%
Color and Shape:
Solid
Molecular weight:
322.31
Ref: TM-T15363
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 271.00 € | ||
| 50mg | 446.00 € | ||
| 100mg | 692.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
TNIK-IN-3
CAS:2754265-25-1
TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase …
Formula:
C23H18FN3O2
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
387.41
Ref: TM-T9556
| 1mg | 104.00 € | ||
| 5mg | 253.00 € | ||
| 10mg | 397.00 € | ||
| 25mg | 638.00 € | ||
| 50mg | 916.00 € | ||
| 100mg | 1,420.00 € | ||
| 1mL*10mM (DMSO) | 277.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
β-catenin/CBP-IN-1
CAS:1198780-38-9
β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-catenin
Formula:
C33H35N6O7P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
658.64
Ref: TM-T12537
| 25mg | 1,837.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Wnt/β-catenin agonist 4
CAS:912784-79-3
Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.
Formula:
C16H15FN4O2
Purity:
99.61%
Color and Shape:
Liquid
Molecular weight:
314.31
Ref: TM-T60803
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 179.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 500.00 € | ||
| 500mg | 1,075.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Gossypolone
CAS:4547-72-2
Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces …
Formula:
C30H26O10
Purity:
96.66%
Color and Shape:
Solid
Molecular weight:
546.52
Ref: TM-T31987
| 1mg | 182.00 € | ||
| 5mg | 417.00 € | ||
| 10mg | 612.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,296.00 € | ||
| 100mg | 1,753.00 € | ||
| 500mg | 3,509.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
JW 67
CAS:442644-28-2
JW 67 is an inhibitor of canonical Wnt pathway signaling.
Formula:
C21H18N2O6
Purity:
97.02%
Color and Shape:
Solid
Molecular weight:
394.38
Ref: TM-T22884
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 430.00 € | ||
| 100mg | 634.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
Toxoflavin
CAS:84-82-2
Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex. Toxoflavin also acts as …
Formula:
C7H7N5O2
Purity:
98.24% - 99.7%
Color and Shape:
Solid
Molecular weight:
193.16
Ref: TM-T17142
| 5mg | 88.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 453.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
Carboxylesterase-IN-3
CAS:2764748-92-5
Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential …
Formula:
C11H6Cl2N4OS
Purity:
97.49% - 97.89%
Color and Shape:
Liquid
Molecular weight:
313.16
Ref: TM-T60788
| 1mg | 90.00 € | ||
| 5mg | 222.00 € | ||
| 10mg | 351.00 € | ||
| 25mg | 602.00 € | ||
| 50mg | 828.00 € | ||
| 100mg | 1,141.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
NRX-103095
CAS:2763260-38-2
NRX-103095 increases β-catenin binding to SCFβ-TrCP E3 ligase; EC50 is 163 nM for pSer33/Ser37 affinity …
Formula:
C22H16Cl2F3N3O3S
Purity:
99.16% - 99.60%
Color and Shape:
Solid
Molecular weight:
530.35
Ref: TM-T63730
| 1mg | 144.00 € | ||
| 5mg | 349.00 € | ||
| 10mg | 564.00 € | ||
| 25mg | 1,119.00 € | ||
| 50mg | 1,802.00 € | ||
| 100mg | 2,702.00 € | ||
| 1mL*10mM (DMSO) | 409.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
NRX-252114
CAS:2763260-39-3
NRX-252114 promotes mutant β-catenin degradation, binding it to E3 ligase SCFβ-TrCP (EC50: 6.5 nM; Kd: …
Formula:
C22H12Cl2F3N3O2S
Purity:
98.26%
Color and Shape:
Liquid
Molecular weight:
510.32
Ref: TM-T63516
| 1mg | 184.00 € | ||
| 5mg | 465.00 € | ||
| 10mg | 671.00 € | ||
| 25mg | 1,049.00 € | ||
| 50mg | 1,420.00 € | ||
| 100mg | 1,838.00 € | ||
| 500mg | 3,687.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
NRX-103094
CAS:2763260-36-0
NRX-103094 boosts β-catenin binding to SCFβ-TrCP ligase with EC50 62 nM and Kd 0.6 nM.
Formula:
C20H11Cl2F3N2O4S
Purity:
99.50%
Color and Shape:
Liquid
Molecular weight:
503.28
Ref: TM-T63427
| 1mg | 72.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 540.00 € | ||
| 50mg | 848.00 € | ||
| 100mg | 1,273.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
