CymitQuimica logo
Tyrosine Kinase/Adaptors

Tyrosine Kinase/Adaptors

Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.

Subcategories of "Tyrosine Kinase/Adaptors"

Show 13 more subcategories

Found 1372 products of "Tyrosine Kinase/Adaptors"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • CymitQuimica logo
    Targetmol
    + Info

    IMPDH2-IN-4

    <p>IMPDH2-IN-4 (compound 2d) is a Mycophenolic acid analog and a selective IMPDH2 inhibitor with a Ki of 1.8 μM. It exhibits potent cytotoxic activity against osteosarcoma cancer cell lines. Additionally, IMPDH2-IN-4 demonstrates high affinity for VEGFR-2, CDK2, and IMPDH.</p>
    Formula:C35H34O6Si
    Color and Shape:Solid
    Molecular weight:578.73

    Ref: TM-T200851

  • CymitQuimica logo
    Targetmol
    + Info

    GIP (1-30) amide, porcine TFA

    <p>GIP (1-30) amide, porcine TFA: a full GIP receptor agonist, similar to natural GIP(1-42), stimulates insulin, mildly inhibits gastric acid.</p>
    Color and Shape:Liquid

    Ref: TM-T37601

  • Leucettine L41
    Targetmol
    + Info

    Leucettine L41

    CAS:
    <p>Leucettine L41 (LeucettineL41) is an inhibitor of DYRKs/CLKs, preferentially targeting DYRK1A, and inhibits DYRK2.</p>
    Formula:C17H13N3O3
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:307.3

    Ref: TM-T24402

  • Oritinib
    Targetmol
    + Info

    Oritinib

    CAS:
    <p>Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (</p>
    Formula:C31H37N7O2
    Purity:99.62%
    Color and Shape:Soild
    Molecular weight:539.67

    Ref: TM-T60076

  • CymitQuimica logo
    Targetmol
    + Info

    Mecbotamab vedotin

    CAS:
    <p>Mecbotamab vedotin (BA301) is an inhibitory IgG1 antibody that targets human tyrosine kinase receptor AXL and the humanized murine monoclonal BA301 γ1 chain. It can be utilized in the preparation of immunoconjugates for research into cancers expressing the Axl type.</p>
    Color and Shape:Liquid

    Ref: TM-T9901A-225

  • LCB 03-0110 dihydrochloride
    Targetmol
    + Info

    LCB 03-0110 dihydrochloride

    CAS:
    <p>LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2</p>
    Formula:C24H25Cl2N3O2S
    Purity:99.9%
    Color and Shape:Soild
    Molecular weight:490.45

    Ref: TM-T32613

  • CLK1-IN-3
    Targetmol
    + Info

    CLK1-IN-3

    CAS:
    <p>Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A.</p>
    Formula:C24H23FN6O
    Purity:98.46% - 99.76%
    Color and Shape:Soild
    Molecular weight:430.48

    Ref: TM-T72039

  • BMS-599626
    Targetmol
    + Info

    BMS-599626

    CAS:
    <p>BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.</p>
    Formula:C27H27FN8O3
    Purity:98.73%
    Color and Shape:Solid
    Molecular weight:530.55

    Ref: TM-T2610

  • Caffeic acid-pYEEIE
    Targetmol
    + Info

    Caffeic acid-pYEEIE

    CAS:
    <p>Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE,).</p>
    Formula:C39H50N5O19P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:923.82

    Ref: TM-TP2053

  • CymitQuimica logo
    Targetmol
    + Info

    Anticancer agent 271

    <p>Anticanceragent 271 (compound 5C) exhibits antiproliferative activity against lung cancer (A549), colon cancer (Caco-2) cell lines, and human lung fibroblasts (WI38), with an IC50 value of 9.18 μM for A549 cells. This compound can downregulate PI3K and mTOR gene expression and is applicable in cancer research.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206744

  • Calcineurin substrate
    Targetmol
    + Info

    Calcineurin substrate

    CAS:
    <p>Calcineurin Substrate is a Peptide from the regulatory RII subunit of cAMP-dependent protein kinase.</p>
    Formula:C92H150N28O29
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2112.35

    Ref: TM-TP1485

  • CymitQuimica logo
    Targetmol
    + Info

    Cetuximab MMAE

    <p>Cetuximab-MMAE, an antibody-drug conjugate (ADC), combines an EGFR-targeting antibody with Monomethyl auristatin E (MMAE) to investigate colorectal and head and neck cancers.</p>
    Color and Shape:Liquid
    Molecular weight:150 kDa

    Ref: TM-T9901A-219

  • ZIGIR
    Targetmol
    + Info

    ZIGIR

    <p>ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.</p>
    Formula:C39H40N6O3
    Purity:98.34% - 99.32%
    Color and Shape:Solid
    Molecular weight:640.77

    Ref: TM-T205819

  • JAK 3 inhibitor IV
    Targetmol
    + Info

    JAK 3 inhibitor IV

    CAS:
    <p>JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to</p>
    Formula:C16H19NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:241.33

    Ref: TM-T2460

  • CymitQuimica logo
    Targetmol
    + Info

    Antiproliferative agent-57

    <p>Antiproliferative agent-57 (compound M2) is a tumor angiogenesis inhibitor that suppresses VEGF secretion in SiHa cells under hypoxic conditions without inducing cytotoxicity (IC50=0.68 μM). It modulates the PI3K/AKT/mTOR and MAPK signaling pathways in tumor cells, thereby inhibiting the expression of HIF-1α and VEGF within tumor tissues.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200522

  • CymitQuimica logo
    Targetmol
    + Info

    JBJ-09-063 TFA

    <p>JBJ-09-063 TFA, an EGFR inhibitor selective for EGFR mutations, IC50s: 0.147-0.396 nM, blocks EGFR/Akt/ERK signaling, for EGFR-mutant lung cancer research.</p>
    Formula:C33H30F4N4O5S
    Color and Shape:Solid
    Molecular weight:670.67

    Ref: TM-T74561

  • KN1022
    Targetmol
    + Info

    KN1022

    CAS:
    <p>KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.</p>
    Formula:C21H22N6O5
    Purity:99.68%
    Color and Shape:Soild
    Molecular weight:438.44

    Ref: TM-T60110

  • CymitQuimica logo
    Targetmol
    + Info

    EGFR-IN-162

    <p>EGFR-IN-162 (compound 20) is an effective EGFR inhibitor that enhances both early and late apoptosis (EGFR) as well as necrosis (necrosis). It shows potential for use in breast cancer research.</p>
    Formula:C27H31N3O2
    Color and Shape:Solid
    Molecular weight:429.24163

    Ref: TM-T207511

  • CymitQuimica logo
    Targetmol
    + Info

    (Pro3) GIP, human

    CAS:
    <p>(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.</p>
    Formula:C226H338N60O64S
    Color and Shape:Solid
    Molecular weight:4951.53

    Ref: TM-T76313

  • CymitQuimica logo
    Targetmol
    + Info

    PROTAC EGFR degrader 2

    <p>Potent PROTAC EGFR degrader 2; IC50: 4.0 nM, DC50: 36.51 nM; inhibits cell growth; for NTR-responsive synthesis.</p>
    Formula:C58H72ClFN12O8S
    Color and Shape:Solid
    Molecular weight:1151.78

    Ref: TM-T74333