Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(123 products)
- CSF-1R(42 products)
- EGFR(591 products)
- Ephrin Receptor(23 products)
- FLT(87 products)
- Fibroblast Growth Factor Receptor (FGFR)(173 products)
- HER(4 products)
- Hck(3 products)
- IGF-1R(102 products)
- PDGFR(126 products)
- PYK2(7 products)
- Src(81 products)
- TAM Receptor(33 products)
- Tie-2(20 products)
- Trk receptor(59 products)
- Tyrosine Kinases(25 products)
- VEGFR(253 products)
- c-Fms(111 products)
- c-Kit(113 products)
- c-Met/HGFR(134 products)
- c-RET(56 products)
Show 13 more subcategories
Found 1259 products of "Tyrosine Kinase/Adaptors"
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7-Hydroxy-4H-chromen-4-one
CAS:7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).Formula:C9H6O3Purity:97.65%Color and Shape:SolidMolecular weight:162.14WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Formula:C16H15N3O2Purity:99.66% - 99.92%Color and Shape:SolidMolecular weight:281.31UNC2250
CAS:<p>UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM).</p>Formula:C24H36N6O2Purity:98.57% - 99.87%Color and Shape:SolidMolecular weight:440.58BTK IN-1
CAS:<p>BTK IN-1 (SNS062 analog) (SNS062 analog) is an effective BTK inhibitor (IC50: <100 nM).</p>Formula:C19H21ClN6OPurity:97.38%Color and Shape:SolidMolecular weight:384.86Tolebrutinib
CAS:<p>Tolebrutinib is an oral, selective BTK inhibitor, effective for MS research, with brain penetration and IC50s of 0.4/0.7 nM in cells.</p>Formula:C26H25N5O3Purity:98.4% - 98.82%Color and Shape:SolidMolecular weight:455.51Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purity:97.89% - 98.66%Color and Shape:SolidMolecular weight:491.39PHA-680632
CAS:<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Formula:C28H35N7O2Purity:98.2%Color and Shape:SolidMolecular weight:501.62EBE-A22
CAS:<p>EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.</p>Formula:C17H16BrN3O2Purity:99.087% - 99.88%Color and Shape:SolidMolecular weight:374.23CNX-2006
CAS:CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.Formula:C26H27F4N7O2Purity:98.85% - 99.16%Color and Shape:SolidMolecular weight:545.53Sapitinib
CAS:Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFormula:C23H25ClFN5O3Purity:98.89% - 99.83%Color and Shape:SolidMolecular weight:473.93WZ-3146
CAS:WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).Formula:C24H25ClN6O2Purity:97.15%Color and Shape:SolidMolecular weight:464.95CZC-8004
CAS:<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34TPX-0046
CAS:<p>TPX-0046 is a RET inhibitor designed to overcome resistance to Selpercatinib and Pralsetinib.</p>Formula:C21H21FN6O3Purity:99.95%Color and Shape:SolidMolecular weight:424.43BAY-474
CAS:BAY-474 is an inhibitor of tyrosine-protein kinase c-Met. It acts as an epigenetics probeFormula:C17H15N5Purity:98.98%Color and Shape:SolidMolecular weight:289.33Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formula:C24H23ClFN5O2Purity:98.37% - 99.84%Color and Shape:Off-White SolidMolecular weight:467.92Selpercatinib
CAS:"Selpercatinib (LOXO-292) is a RET tyrosine kinase inhibitor with IC50s of 14.0, 24.1, 530.7 nM for different RET mutations."Formula:C29H31N7O3Purity:99.89% - >99.99%Color and Shape:SolidMolecular weight:525.6GW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Formula:C20H22N4O3Purity:99.48% - >99.99%Color and Shape:SolidMolecular weight:366.41NVP-ACC789
CAS:<p>ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.</p>Formula:C21H17BrN4Purity:99.44% - 99.63%Color and Shape:SolidMolecular weight:405.29Olmutinib
CAS:<p>Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.</p>Formula:C26H26N6O2SPurity:99.63%Color and Shape:SolidMolecular weight:486.59Almonertinib mesylate
CAS:Almonertinib mesylate: EGFR tyrosine kinase inhibitor, targets EGFR-mutant non-small cell lung cancer.Formula:C31H39N7O5SPurity:99.92%Color and Shape:SolidMolecular weight:621.75
