Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(123 products)
- CSF-1R(42 products)
- EGFR(591 products)
- Ephrin Receptor(23 products)
- FLT(87 products)
- Fibroblast Growth Factor Receptor (FGFR)(173 products)
- HER(4 products)
- Hck(3 products)
- IGF-1R(102 products)
- PDGFR(126 products)
- PYK2(7 products)
- Src(81 products)
- TAM Receptor(33 products)
- Tie-2(20 products)
- Trk receptor(59 products)
- Tyrosine Kinases(25 products)
- VEGFR(253 products)
- c-Fms(111 products)
- c-Kit(113 products)
- c-Met/HGFR(134 products)
- c-RET(56 products)
Show 13 more subcategories
Found 1259 products of "Tyrosine Kinase/Adaptors"
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A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Formula:C29H37Cl3N6OPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:592EGFR-IN-99
CAS:<p>EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).</p>Formula:C25H22FN7O3Purity:97.75%Color and Shape:SolidMolecular weight:487.49TG-89
CAS:<p>TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian and</p>Formula:C26H34N6O3SPurity:98.68%Color and Shape:SolidMolecular weight:510.65A-935142
CAS:A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.Formula:C18H19F3N2O2Purity:98.97% - 99.91%Color and Shape:SolidMolecular weight:352.35EMI1
CAS:<p>EMI1 targets mutated EGFR in drug-resistant NSCLC research.</p>Formula:C20H18N2O3Purity:99.96%Color and Shape:SolidMolecular weight:334.37Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Formula:C27H21N3O3Purity:99.22%Color and Shape:SolidMolecular weight:435.47PKI-166
CAS:<p>PKI-166: oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM), halts growth & spread of many human cancers, including pancreatic.</p>Formula:C20H18N4OPurity:99.2%Color and Shape:SolidMolecular weight:330.38Rezivertinib
CAS:Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.Formula:C27H30N6O3Purity:99.26% - 99.98%Color and Shape:SolidMolecular weight:486.57RET-IN-3
CAS:<p>RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.</p>Formula:C18H21N5O2Purity:99.52%Color and Shape:SolidMolecular weight:339.39JND3229
CAS:JND3229 inhibits EGFRC797S; IC50: 5.8-30.5 nM; halts cell growth; effective in non-small cell lung cancer study.Formula:C33H41ClN8O2Purity:98.75%Color and Shape:SolidMolecular weight:617.18EGFR-IN-36
CAS:EGFR-IN-36 inhibits EGFR, HER2, & mutants with IC50s: 19.09 nM (EGFR WT), 120.01 nM (HER2 WT), 2.35 nM (HER2 mutant).Formula:C26H25ClN6O2Color and Shape:SolidMolecular weight:488.97EGFR-IN-1
CAS:<p>EGFR-IN-1: an oral, irreversible EGFR inhibitor targeting L858R/T790M mutations with high selectivity, showing potent antitumor effects.</p>Formula:C28H30N6O4Purity:98%Color and Shape:SolidMolecular weight:514.58ARRY-382
CAS:<p>ARRY-382 is a highly selective oral inhibitor of CSF-1R with an IC50 of 9 nM.</p>Formula:C32H36N8O2Purity:99.76%Color and Shape:SolidMolecular weight:564.68TRK-IN-24
CAS:TRK-IN-24 (compound 10g) is a selective inhibitor of Trk receptors, effectively targeting TRKA, TRKC, and mutant forms TRKA G595R, TRKA G667C, and TRKA F589L,Formula:C39H45N7O3Purity:98%Color and Shape:SolidMolecular weight:659.82FGFR4-IN-8
CAS:FGFR4-IN-8 is a selective, ATP-competitive FGFR4 inhibitor with IC50s as low as 0.25 nM, halting growth of Hep3B cells at 29 nM and showing in vivo efficacy.Formula:C32H34Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:654.56UniPR505
CAS:<p>UniPR505 is a potent EphA2 antagonist (IC50: 0.95 µM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.</p>Formula:C39H57N3O5Purity:98.23%Color and Shape:SolidMolecular weight:647.89Brepocitinib
CAS:Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).Formula:C18H21F2N7OPurity:99.82%Color and Shape:SolidMolecular weight:389.4EGFR-IN-71
CAS:<p>EGFR-IN-71 is a potent inhibitor of epidermal growth factor receptor (EGFR) (IC50= 3.7 μM). EGFR-IN-71 has research value in chordoma.</p>Formula:C16H9ClIN3Color and Shape:SolidMolecular weight:405.622′-Thioadenosine
CAS:<p>2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 µM against</p>Formula:C10H13N5O3SPurity:98%Color and Shape:SolidMolecular weight:283.31Cinsebrutinib
CAS:<p>Cinsebrutinib, a Bruton's tyrosine kinase inhibitor, holds potential for research in cancer treatment.</p>Formula:C22H26FN3O2Purity:98%Color and Shape:SolidMolecular weight:383.46
