Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(116 products)
- CSF-1R(42 products)
- EGFR(572 products)
- Ephrin Receptor(23 products)
- FLT(91 products)
- Fibroblast Growth Factor Receptor (FGFR)(169 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(92 products)
- PDGFR(126 products)
- PYK2(7 products)
- Src(80 products)
- TAM Receptor(32 products)
- Tie-2(21 products)
- Trk receptor(59 products)
- Tyrosine Kinases(26 products)
- VEGFR(262 products)
- c-Fms(108 products)
- c-Kit(102 products)
- c-Met/HGFR(129 products)
- c-RET(51 products)
Show 13 more subcategories
Found 1342 products of "Tyrosine Kinase/Adaptors"
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c-Kit-IN-2
CAS:c-Kit-IN-2 is a c-KIT inhibitor (IC50: 82 nM), shows superior antiproliferative activities against all the three GIST cell lines, GIST430, GIST882, and GIST48 (Formula:C25H29N9O2SPurity:98%Color and Shape:SolidMolecular weight:519.62JNJ28871063 hydrochloride
CAS:<p>ErbB receptor family inhibitor</p>Formula:C24H28Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:519.42EGFR-IN-55
CAS:<p>"EGFR-IN-55 targets EGFRWT (70 nM IC50) & EGFRL858R/T790M (3.9 nM IC50), halts NCI-H1975 cell cycle in G0/G1, showing anticancer properties."</p>Formula:C25H25Cl2N7O2Color and Shape:SolidMolecular weight:526.42EGFR-IN-49
CAS:<p>EGFR-IN-49 selectively inhibits EGFR mutations T790M (IC50: 65 nM) & T790M/L858R (IC50: 13.6 nM), triggering apoptosis dose-dependently.</p>Formula:C22H15N5O2SColor and Shape:SolidMolecular weight:413.45Limertinib
CAS:<p>Limertinib (ASK120067) is a EGFR tyrosine kinase inhibitor targeting EGFR T790M, applicable for the study of non-small cell lung cancer.</p>Formula:C29H32ClN7O2Purity:97.44%Color and Shape:SolidMolecular weight:546.06RU-302
CAS:<p>RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain.</p>Formula:C24H24F3N3O2SPurity:99.84%Color and Shape:SolidMolecular weight:475.53(E/Z)-CP-724714
CAS:<p>(E/Z)-CP-724714, comprising racemic mixtures of (E)-CP-724714 and (Z)-CP-724714 isomers, is a potent, selective, and orally active inhibitor of ErbB2 (HER2)[1].</p>Formula:C27H27N5O3Purity:98%Color and Shape:SolidMolecular weight:469.54EGFR/HER2-IN-9
CAS:<p>EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR</p>Formula:C25H25ClFN5O4Color and Shape:SolidMolecular weight:513.95Tyrphostin 51
CAS:<p>Tyrphostin 51 is an effective inhibitor of EGFR kinase.</p>Formula:C13H8N4O3Purity:98%Color and Shape:SolidMolecular weight:268.23ML 315
CAS:ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.Formula:C18H13Cl2N3O2Purity:99.08%Color and Shape:SolidMolecular weight:374.22(Z)-FeCP-oxindole
CAS:<p>(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.</p>Formula:C19H15FeNOPurity:99.63% - 99.84%Color and Shape:SolidMolecular weight:329.17(±)-Zanubrutinib
CAS:<p>(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability,</p>Formula:C27H29N5O3Purity:99.09%Color and Shape:SolidMolecular weight:471.55PD 174265
CAS:<p>PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.</p>Formula:C17H15BrN4OPurity:99.51%Color and Shape:SolidMolecular weight:371.23Larotinib
CAS:<p>Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.</p>Formula:C24H26ClFN4O4Purity:98.45%Color and Shape:SolidMolecular weight:488.94(R)-Zanubrutinib
CAS:<p>(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).</p>Formula:C27H29N5O3Purity:99.55%Color and Shape:SolidMolecular weight:471.55CLK-IN-T3
CAS:CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.Formula:C28H30N6O2Purity:99.61%Color and Shape:SolidMolecular weight:482.58YK-2-69
CAS:YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.Formula:C25H27FN8OSPurity:98.61% - 99.64%Color and Shape:SolidMolecular weight:506.6INDY
CAS:<p>INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.</p>Formula:C12H13NO2SPurity:99.26%Color and Shape:SolidMolecular weight:235.3Sunvozertinib
CAS:<p>Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2.Cost-effective and quality-assured.</p>Formula:C29H35ClFN7O3Purity:98.11% - 99.63%Color and Shape:SolidMolecular weight:584.08TG-89
CAS:<p>TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian and</p>Formula:C26H34N6O3SPurity:98.68%Color and Shape:SolidMolecular weight:510.65
