Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(135 products)
- CSF-1R(42 products)
- EGFR(561 products)
- Ephrin Receptor(25 products)
- FLT(89 products)
- Fibroblast Growth Factor Receptor (FGFR)(177 products)
- HER(5 products)
- Hck(3 products)
- IGF-1R(99 products)
- PDGFR(127 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(34 products)
- Tie-2(20 products)
- Trk receptor(53 products)
- Tyrosine Kinases(14 products)
- VEGFR(239 products)
- c-Fms(105 products)
- c-Kit(113 products)
- c-Met/HGFR(137 products)
- c-RET(61 products)
Show 13 more subcategories
Found 1045 products of "Tyrosine Kinase/Adaptors"
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EGFR WT/T790M/L858R-IN-1
EGFRWT/T790M/L858R-IN-1 (compound 10d) is a potent inhibitor of EGFR, demonstrating IC50 values of 0.097, 0.280, and 0.051 μM for EGFRWT, EGFRT790M, and EGFRL858R, respectively. This compound can be utilized in cancer research.Formula:C26H25Cl3N2O3Molecular weight:518.09308PKG inhibitor peptide
CAS:PKG inhibitor; mimics H2B phosphorylation site; Ki=86mM; blocks synthetic substrates, not histone phosphorylation; stops PKA activity on histones.Formula:C38H74N18O10Purity:98%Color and Shape:SolidMolecular weight:943.12EGFR-IN-95
EGFR-IN-95 is a derivative of 2,4-diaminonicotinamide. It effectively inhibits the activity of EGFRdel19/T790M/C797S and L858R/T790M/C797S.Formula:C23H28F2N8O3SMolecular weight:534.19731PROTAC EGFR degrader 2
Potent PROTAC EGFR degrader 2; IC50: 4.0 nM, DC50: 36.51 nM; inhibits cell growth; for NTR-responsive synthesis.Formula:C58H72ClFN12O8SColor and Shape:SolidMolecular weight:1151.78EP26
EP26 is an orally active and potent inhibitor of EGFR and PD-L1, with IC50 values of 48.6 nM and 1.77 µM, respectively. It reduces the protein expression of p-EGFR and induces cell cycle arrest at the G0/G1 phase. EP26 shows potential for glioblastoma research.Formula:C42H42ClFN4O5Molecular weight:736.28278Tephrosin
CAS:Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.Formula:C23H22O7Purity:98%Color and Shape:SolidMolecular weight:410.42CRB-0089
CRB-0089 is a human monoclonal antibody targeting NGF/bNGF. It is used in the study of analgesia.Color and Shape:Odour LiquidEGFR-IN-116
EGFR-IN-116 (compound 14D) is an antineoplastic agent. It exhibits an IC50 value of 0.103 μM for EGFR, 0.069 μM for VEGFR-2, and 19.74 μM for Topo II.Formula:C26H22N6O2SMolecular weight:482.1525EGFR/HER2-IN-15
EGFR/HER2-IN-15 is a dihydropyrimidine and an effective inhibitor of EGFR/HER2. It significantly suppresses EGFRwt activity with an IC50 of 37.21 nM and exhibits anticancer properties.Formula:C28H29N3O6Molecular weight:503.20564MS39N
CAS:MS39N (compound 27) serves as the negative control for MS39, capable of binding to EGFR without causing its degradation.Formula:C55H71ClFN9O7SMolecular weight:1056.73FDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Color and Shape:LiquidC-Met inhibitor D9
CAS:C-Met inhibitor D9 is a c-Met kinase inhibitor.Formula:C17H15N3O2Purity:97.45%Color and Shape:SolidMolecular weight:293.32EGFR-IN-22
CAS:EGFR-IN-22: potent for EGFR (IC50: 4.91 nM) & L858R/T790M/C797S mutation (IC50: 0.54 nM).Formula:C38H47BrFN10O2PColor and Shape:SolidMolecular weight:805.72DSPE-PEG2000-GE11
DSPE-PEG2000-GE11 is a PEG compound composed of DSPE and an EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells that overexpress EGFR. DSPE-PEG2000-GE11 is utilized in drug delivery.Color and Shape:Odour SolidCalcineurin substrate
CAS:Calcineurin Substrate is a Peptide from the regulatory RII subunit of cAMP-dependent protein kinase.Formula:C92H150N28O29Purity:98%Color and Shape:SolidMolecular weight:2112.35GNF-8625 monopyridin-N-piperazine hydrochloride
CAS:GNF-8625 monopyridin-N-piperazine hydrochloride is a protomyosin receptor kinase (TRK) inhibitor.Formula:C25H27ClFN7Purity:98.97%Color and Shape:SolidMolecular weight:479.98Kemptide Phospho-Ser5
Kemptide (Phospho-Ser5) is a phosphoreceptor peptide that is a specific substrate for camp-dependent protein kinase (PKA).Formula:C32H62N13O12PPurity:98%Color and Shape:SolidMolecular weight:851.89MS9427
CAS:MS9427: PROTAC EGFR degrader, 7.1 nM (WT), 4.3 nM (L858R); targets mutant via UPS and autophagy; inhibits NSCLC cell growth; anticancer research.Formula:C48H58ClFN8O12Color and Shape:SolidMolecular weight:993.47Anticancer agent 271
Anticanceragent 271 (compound 5C) exhibits antiproliferative activity against lung cancer (A549), colon cancer (Caco-2) cell lines, and human lung fibroblasts (WI38), with an IC50 value of 9.18 μM for A549 cells. This compound can downregulate PI3K and mTOR gene expression and is applicable in cancer research.Color and Shape:Odour SolidAG-1478 hydrochloride
CAS:AG1478 HCl is an epidermal growth factor receptor protein inhibitor.Formula:C16H15Cl2N3O2Color and Shape:SolidMolecular weight:352.21
