Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
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Subcategories of "Tyrosine Kinase/Adaptors"
ALK
CSF-1R
EGFR
Ephrin Receptor
FLT
Fibroblast Growth Factor Receptor (FGFR)
HER
Hck
IGF-1R
PDGFR
PYK2
Src
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
c-Fms
c-Kit
c-Met/HGFR
c-RET
Show 13 more subcategories
Products of "Tyrosine Kinase/Adaptors"
Sitravatinib
CAS:1123837-84-2
Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, …
Formula:
C33H29F2N5O4S
Purity:
98.9% - 99.74%
Color and Shape:
Solid
Molecular weight:
629.68
Ref: TM-T4349
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 134.00 € | ||
| 50mg | 206.00 € | ||
| 100mg | 330.00 € | ||
| 200mg | 523.00 € | ||
| 500mg | 829.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
4SC-203
CAS:895533-09-2
4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.
Formula:
C33H38N8O4S
Purity:
96.4% - 99.73%
Color and Shape:
Solid
Molecular weight:
642.77
Ref: TM-T9473
| 1mg | 73.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 244.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 606.00 € | ||
| 100mg | 861.00 € | ||
| 1mL*10mM (DMSO) | 214.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD153035
CAS:153436-54-5
PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in …
Formula:
C16H14BrN3O2
Purity:
98.92% - 99.31%
Color and Shape:
Solid
Molecular weight:
360.21
Ref: TM-T2041
| 10mg | 41.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 128.00 € | ||
| 100mg | 216.00 € | ||
| 200mg | 323.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KHS101 hydrochloride
CAS:1784282-12-7
KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.
Formula:
C18H22ClN5S
Purity:
99.6%
Color and Shape:
Solid
Molecular weight:
375.92
Ref: TM-T5170
| 1mg | 42.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 125.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 414.00 € | ||
| 100mg | 609.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
hVEGF-IN-1
CAS:1637443-98-1
hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.
Formula:
C34H43N7O2
Purity:
100% - 98.85%
Color and Shape:
Solid
Molecular weight:
581.75
Ref: TM-T4288
| 1mg | 62.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 173.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 588.00 € | ||
| 200mg | 794.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ENMD-2076
CAS:934353-76-1
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, …
Formula:
C21H25N7
Purity:
97.63% - ≥95%
Color and Shape:
Solid
Molecular weight:
375.47
Ref: TM-T2358
| 1mg | 51.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 156.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 638.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nazartinib
CAS:1508250-71-2
Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory …
Formula:
C26H31ClN6O2
Purity:
98% - ≥95%
Color and Shape:
Solid Powder
Molecular weight:
495.02
Ref: TM-T3506
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 500mg | 1,133.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DGY-06-116
DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value …
Formula:
C32H33ClN8O2
Purity:
97.65%
Color and Shape:
Solid
Molecular weight:
597.11
Ref: TM-T22306
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 179.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 414.00 € | ||
| 200mg | 585.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD-089828
CAS:179343-17-0
PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).
Formula:
C18H18Cl2N6O
Purity:
96.78%
Color and Shape:
Solid
Molecular weight:
405.28
Ref: TM-T8976
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 365.00 € | ||
| 100mg | 537.00 € | ||
| 500mg | 1,137.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AST 487
CAS:630124-46-8
AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of …
Formula:
C26H30F3N7O2
Purity:
98.17% - 99.56%
Color and Shape:
Solid
Molecular weight:
529.56
Ref: TM-T4053
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 500mg | 1,133.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD173955
CAS:260415-63-2
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes …
Formula:
C21H16Cl2N4OS
Purity:
98.52% - 99.28%
Color and Shape:
Solid
Molecular weight:
443.35
Ref: TM-T3063
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 640.00 € | ||
| 1mL*10mM (DMSO) | 163.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
A 419259
CAS:364042-47-7
A 419259 is a pyrrolo-pyrimidine inhibitor, designed to enhance selectivity towards the Src family (IC50s: …
Formula:
C29H34N6O
Color and Shape:
Solid
Molecular weight:
482.62
Ref: TM-T10206
| 2mg | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GluR6 antagonist-1
CAS:323176-64-3
GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.
Formula:
C15H11ClN2OS
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
302.78
Ref: TM-T9723
| 2mg | 37.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 284.00 € | ||
| 200mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Vactosertib Hydrochloride
CAS:1352610-25-3
Vactosertib HCl: oral ATP-competitive ALK5 inhibitor, IC50=12.9 nM; anticancer, antimetastatic, also targets ALK2/4.
Formula:
C22H19ClFN7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
435.89
Ref: TM-T15262
| 2mg | 84.00 € | ||
| 5mg | 99.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
A 83-01 sodium salt
CAS:2828431-89-4
A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 …
Formula:
C25H19N5NaS
Color and Shape:
Solid
Molecular weight:
444.51
Ref: TM-T10442
| 500mg | 3,969.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BMS-690514
CAS:859853-30-8
BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s …
Formula:
C19H24N6O2
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
368.43
Ref: TM-T14677
| 2mg | 136.00 € | ||
| 5mg | 222.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
BIBF 1202
CAS:894783-71-2
BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).
Formula:
C30H31N5O4
Purity:
98.04%
Color and Shape:
Solid
Molecular weight:
525.6
Ref: TM-TQ0321
| 5mg | 103.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 292.00 € | ||
| 50mg | 432.00 € | ||
| 100mg | 633.00 € | ||
| 500mg | 1,332.00 € | ||
| 1mL*10mM (DMSO) | 115.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Almonertinib hydrochloride
CAS:2134096-03-8
Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation.
Formula:
C30H36ClN7O2
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
562.1
Ref: TM-T5675
| 1mg | 90.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 525.00 € | ||
| 50mg | 740.00 € | ||
| 100mg | 981.00 € | ||
| 500mg | 1,989.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
NVP-BSK805
CAS:1092499-93-8
NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.
Formula:
C27H28F2N6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
490.55
Ref: TM-T5049
| 1mg | 61.00 € | ||
| 5mg | 129.00 € | ||
| 10mg | 209.00 € | ||
| 25mg | 402.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
(Rac)-SAR131675
CAS:1092539-44-0
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and …
Formula:
C18H22N4O4
Purity:
98.34% - 99.1%
Color and Shape:
Solid
Molecular weight:
358.39
Ref: TM-T3691
| 1mg | 35.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 329.00 € | ||
| 200mg | 459.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
