Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(129 products)
- CSF-1R(42 products)
- EGFR(593 products)
- Ephrin Receptor(25 products)
- FLT(90 products)
- Fibroblast Growth Factor Receptor (FGFR)(183 products)
- HER(3 products)
- Hck(3 products)
- IGF-1R(103 products)
- PDGFR(127 products)
- PYK2(7 products)
- Src(81 products)
- TAM Receptor(33 products)
- Tie-2(20 products)
- Trk receptor(57 products)
- Tyrosine Kinases(25 products)
- VEGFR(245 products)
- c-Fms(112 products)
- c-Kit(114 products)
- c-Met/HGFR(137 products)
- c-RET(62 products)
Show 13 more subcategories
Found 1170 products of "Tyrosine Kinase/Adaptors"
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AG-1478 hydrochloride
CAS:AG1478 HCl is an epidermal growth factor receptor protein inhibitor.Formula:C16H15Cl2N3O2Color and Shape:SolidMolecular weight:352.21GIP (1-30) amide,human
CAS:GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.Formula:C162H240N40O47SPurity:98%Color and Shape:SolidMolecular weight:3531.94PKG inhibitor peptide
CAS:<p>PKG inhibitor; mimics H2B phosphorylation site; Ki=86mM; blocks synthetic substrates, not histone phosphorylation; stops PKA activity on histones.</p>Formula:C38H74N18O10Purity:98%Color and Shape:SolidMolecular weight:943.12EGFR/PI3Kα-IN-1
EGFR/PI3Kα-IN-1 (compound 30k), a dual EGFR/PI3Kα inhibitor, exhibits potent activity with IC 50 values of 3.6 nM (EGFRL858R/T790M) and 30 nM (PI3Kα). It effectively inhibits tumor cell proliferation and demonstrates significant anticancer activity.Formula:C50H49N11O5SColor and Shape:SolidMolecular weight:916.06Tephrosin
CAS:Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.Formula:C23H22O7Purity:98%Color and Shape:SolidMolecular weight:410.42Cixutumumab
CAS:Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor activation, impedingPurity:98.5% (SDS-PAGE); 97.5% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:LiquidFDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Color and Shape:LiquidHER2/neu (654-662) GP2
CAS:Phage display selected Affibody ligands for HER2/neu from a protein library based on a 58-residue Staphylococcal protein A Z domain.Formula:C42H77N9O11Purity:98%Color and Shape:SolidMolecular weight:884.11Anticancer agent 271
Anticanceragent 271 (compound 5C) exhibits antiproliferative activity against lung cancer (A549), colon cancer (Caco-2) cell lines, and human lung fibroblasts (WI38), with an IC50 value of 9.18 μM for A549 cells. This compound can downregulate PI3K and mTOR gene expression and is applicable in cancer research.Color and Shape:Odour SolidALW-II-49-7
CAS:<p>ALW-II-49-7 is a selective and potent inhibitor of EphB2 kinase with an EC50 value of 40 nM in cell.</p>Formula:C21H17F3N4O2Purity:99.72%Color and Shape:SoildMolecular weight:414.38WAY-270360
CAS:WAY-270360 (N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide) is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.Formula:C22H19N3O3Purity:98.05%Color and Shape:SolidMolecular weight:373.4DSPE-PEG2000-GE11
<p>DSPE-PEG2000-GE11 is a PEG compound composed of DSPE and an EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells that overexpress EGFR. DSPE-PEG2000-GE11 is utilized in drug delivery.</p>Color and Shape:Odour SolidMatuzumab
CAS:Matuzumab (EMD 72000) is a humanized monoclonal antibody targeting EGFR that can be used to study non-small cell lung cancer.Purity:95%Color and Shape:LiquidMolecular weight:145.9 kDaGW 583340
CAS:GW 583340 is a potent and selective dual inhibitor of EGFR/ErbB2 tyrosine kinase with the advantage of oral dosability and antitumor effects.Formula:C28H25ClFN5O3S2Purity:98.68%Color and Shape:SoildMolecular weight:598.11Ref: TM-T22827L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€200mg2,555.00€MS9427
CAS:MS9427: PROTAC EGFR degrader, 7.1 nM (WT), 4.3 nM (L858R); targets mutant via UPS and autophagy; inhibits NSCLC cell growth; anticancer research.Formula:C48H58ClFN8O12Color and Shape:SolidMolecular weight:993.47ARRY-380 (analog )
CAS:ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor.Formula:C29H27N7O4SPurity:99.82%Color and Shape:SolidMolecular weight:569.63Ref: TM-T2518
1mg35.00€2mg49.00€5mg74.00€10mg110.00€25mg180.00€50mg266.00€100mgTo inquire1mL*10mM (DMSO)96.00€PKI (5-24),amide
CAS:PKI (5-24),amide is a 20-residue peptide, a potent PKA inhibitor with a Ki of 2.3 nM, derived from a cAMP inhibitor protein.Formula:C94H149N33O30Color and Shape:SolidMolecular weight:2221.4Insulin efsitora alfa
CAS:Insulin efsitora alfa(LY-3209590) is an IR agonist and a fusion protein that binds a novel single-chain insulin variant to the structural domain of human IgG FcPurity:98.3% (SDS-PAGE); 98.1% (SEC-HPLC) - 98.3% (SDS-PAGE); 98.1% (SEC-HPLC)Color and Shape:LiquidPF-04217903 phenolsulfonate
CAS:PF-04217903 phenolsulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).Formula:C25H22N8O5SPurity:98%Color and Shape:SolidMolecular weight:546.56KYL peptide
CAS:EphA4 inhibitor, Kd 0.8 μM, blocks EphA4-EphrinA5; avoids AβO damage, preserves spines & LTP; long half-life (8-12h), neuroprotective.Formula:C74H108N14O17Purity:98%Color and Shape:SolidMolecular weight:1465.75
