Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
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Subcategories of "Tyrosine Kinase/Adaptors"
ALK
CSF-1R
EGFR
Ephrin Receptor
FLT
Fibroblast Growth Factor Receptor (FGFR)
HER
Hck
IGF-1R
PDGFR
PYK2
Src
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
c-Fms
c-Kit
c-Met/HGFR
c-RET
Show 13 more subcategories
Products of "Tyrosine Kinase/Adaptors"
Ropsacitinib
CAS:2127109-84-4
Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain …
Formula:
C20H17N9
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
383.41
Ref: TM-T13237L
| 1mg | 226.00 € | ||
| 2mg | 339.00 € | ||
| 5mg | 481.00 € | ||
| 10mg | 696.00 € | ||
| 25mg | 1,077.00 € | ||
| 50mg | 1,458.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
DYRKs-IN-2
CAS:1386980-04-6
DYRKs-IN-2 has antitumor activity. DYRKs-IN-2 is a potent DYRKs inhibitor with IC50s of 30.6 nM …
Formula:
C32H38ClN9O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
632.16
Ref: TM-T11133
| 25mg | 1,967.00 € | ||
| 50mg | 2,592.00 € | ||
| 100mg | 3,450.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
BMS-935177
CAS:1231889-53-4
BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.
Formula:
C31H26N4O3
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
502.56
Ref: TM-T14681
| 1mg | 42.00 € | ||
| 2mg | 67.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
c-met-IN-1
CAS:2084836-84-8
c-met-IN-1 is a potent and selective c-Met inhibitor (IC50: 1.1 nM) with antitumor activity.
Formula:
C35H37FN6O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
640.7
Ref: TM-T10653
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
HKI-357
CAS:848133-17-5
HKI-357 irreversibly inhibits EGFR/ERBB2 (IC50: 34/33 nM), blocks EGFR Y1068 autophosphorylation, and AKT/MAPK phosphorylation.
Formula:
C31H29ClFN5O3
Purity:
95.11%
Color and Shape:
Solid
Molecular weight:
574.05
Ref: TM-T11569
| 1mg | 78.00 € | ||
| 5mg | 149.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 452.00 € | ||
| 50mg | 647.00 € | ||
| 100mg | 920.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
BMX-IN-1
CAS:1431525-23-3
BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome …
Formula:
C29H24N4O4S
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
524.59
Ref: TM-T14692
| 1mg | 52.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 388.00 € | ||
| 50mg | 543.00 € | ||
| 100mg | 744.00 € | ||
| 1mL*10mM (DMSO) | 154.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
PF-06250112
CAS:1609465-89-5
PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM.
Formula:
C22H20F2N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
438.43
Ref: TM-T12673L
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
APG-2449
CAS:2196186-84-0
APG-2449 is an orally active inhibitor targeting ALK, ROS1, and FAK, demonstrating antitumor efficacy in …
Formula:
C33H42ClN5O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
640.24
Ref: TM-T79363
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
PF-06459988
CAS:1428774-45-1
PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) …
Formula:
C19H22ClN7O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
431.88
Ref: TM-T16492
| 1mg | 143.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
AXL-IN-14
CAS:2947506-65-0
AXL-IN-14: orally active, potent AXL inhibitor (IC50=0.8 nM); hinders Gas6/AXL migration, invasion; lowers p-AXL, p-AKT; …
Formula:
C32H24F2N4O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
566.55
Ref: TM-T73310
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
CP-547632 TFA
CAS:2805804-54-8
CP-547632 TFA, an oral VEGFR-2 and FGF inhibitor, IC50: VEGFR-2 at 11 nM, FGF at …
Formula:
C22H25BrF5N5O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
646.43
Ref: TM-T74000
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
DZD1516
CAS:2387570-00-3
DZD1516, a potent and selective HER2 inhibitor (IC50 = 0.56 nM), demonstrates good blood-brain barrier …
Formula:
C28H27F2N7O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
547.56
Ref: TM-T79297
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
2′-Thioadenosine
CAS:136904-69-3
2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, …
Formula:
C10H13N5O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
283.31
Ref: TM-T78634
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Tyrosine kinase-IN-6
CAS:2377507-01-0
Tyrosine kinase-IN-6 is a potent inhibitor of RON splice variants, demonstrating significant anticancer and antineoplastic …
Formula:
C37H31F2N5O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
695.73
Ref: TM-T79612
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
YK-029A
CAS:2064269-82-3
YK-029A, an orally active EGFR mutant inhibitor, targets both EGFR T790M and EGFRex20ins mutations.
Formula:
C27H32N8O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
500.6
Ref: TM-T79461
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
ALK/EGFR-IN-1
CAS:2730430-08-5
ALK/EGFR-IN-1 (Compound 8l) is a dual inhibitor targeting both ALK and EGFR, effectively blocking their …
Formula:
C27H34ClN7O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
572.12
Ref: TM-T79392
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
EGFR/CSC-IN-1
CAS:2820447-02-5
EGFR/CSC-IN-1 is a dual inhibitor targeting both the epidermal growth factor receptor (EGFR [IC50 10.52 …
Formula:
C54H54Cl2FN7O7S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1067.08
Ref: TM-T73995
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 10 Feb 2025
ENT-C225
CAS:2919962-53-9
ENT-C225 is a potent TrkB neurotrophin receptor (TrkBR) activator with neuroprotective activity for the study …
Formula:
C26H40N4O5
Purity:
99.16% - 99.16%
Color and Shape:
Solid
Molecular weight:
488.62
Ref: TM-T73397
| 1mg | 183.00 € | ||
| 5mg | 452.00 € | ||
| 10mg | 647.00 € | ||
| 25mg | 1,009.00 € | ||
| 50mg | 1,392.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
FGFR-IN-11
CAS:2658488-68-5
FGFR-IN-11 (compound I-5) is an orally active, covalent inhibitor of FGFR, exhibiting IC50 values of …
Formula:
C28H29ClN4O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
521.01
Ref: TM-T79257
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
Type II TRK inhibitor 1
CAS:2937543-72-9
Type II TRK Inhibitor 1 is a potent inhibitor targeting multiple tropomyosin receptor kinase (TRK) …
Formula:
C35H33F3N8O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
670.68
Ref: TM-T72289
| 5mg | 1,290.00 € | ||
| 50mg | 2,618.00 € | ||
| 100mg | 3,484.00 € |
Estimated delivery in United States, on Monday 10 Feb 2025
