Fibroblast Growth Factor Receptor (FGFR)
FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.
Found 180 products of "Fibroblast Growth Factor Receptor (FGFR)"
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Vosoritide
CAS:Vosoritide (BMN 111), a CNP analogue, targets NPR-B, inhibits FGFR3, aiding achondroplasia, dwarfism study.Formula:C176H290N56O51S3Color and Shape:SolidMolecular weight:4102.73ODM-203 sodium
ODM-203 sodium is an orally bioavailable selective and efficient FGFR and VEGFR inhibitor with antitumor activity, used in solid tumor research.Formula:C26H20F2N5NaO2SPurity:99.89%Color and Shape:SolidMolecular weight:527.52Recifercept
CAS:Recifercept (TA-46) is a recombinant human soluble fibroblast growth factor receptor 3, a decoy protein that competes for ligands of mutant FGFR3.Purity:98.8% (SDS-PAGE); 98.4% (SEC-HPLC) - 98.8% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:LiquidFGFR-IN-14
FGFR-IN-14 (compound 10h) is a pan-FGFR inhibitor. It effectively inhibits FGFR1, FGFR2, FGFR3, and the FGFR2V564F gatekeeper mutant, with IC50 values of 46, 41, 99, and 62 nM, respectively. Additionally, FGFR-IN-14 demonstrates strong antiproliferative effects on NCI-H520 lung cancer cells and SNU-16 and KATO III gastric cancer cells, with IC50 values of 19, 59, and 73 nM, respectively.Formula:C24H19F2N7O2Molecular weight:475.15683FGFR4-IN-20
FGFR4-IN-20 (comp 11) is an orally active and selective FGFR4 inhibitor, demonstrating IC50 values of 19 nM against Huh7 cells and 36 nM for FGFR4 kinase. It is utilized in hepatocellular carcinoma research.Formula:C26H22Cl2N4O3Molecular weight:508.1069U3-1784
U3-1784 is a humanized monoclonal antibody targeting CD334, with anti-cancer activity, used in liver cancer research.Color and Shape:LiquidMolecular weight:143.22 kDaS6K2-IN-1
S6K2-IN-1 (Compound 2) is an inhibitor of S6K2 with an IC50 of 22 nM and also exhibits inhibitory activity against FGFR4 with an IC50 of 216 nM.Formula:C24H23ClF3N9O2Purity:98%Color and Shape:SolidMolecular weight:561.95PD 173074
CAS:Formula:C28H41N7O3Purity:>95.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:523.68(Z)-Orantinib
CAS:(Z)-Orantinib ((Z)-SU6668) is an orally active ATP-competitive inhibitor of Flk-1/KDR, PDGFRβ, and FGFR1, acting as a potent anti-angiogenic and anti-tumor agent.Formula:C18H18N2O3Purity:98.05%Color and Shape:SolidMolecular weight:310.35NSC 12
CAS:NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.Formula:C24H34F6O3Purity:99.51%Color and Shape:SolidMolecular weight:484.52Nintedanib
CAS:Formula:C31H33N5O4Purity:>95.0%(T)(HPLC)Color and Shape:White to Yellow to Yellow green powder to crystalMolecular weight:539.64SM27
CAS:SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.Formula:C21H16N2O9S2Purity:98.83%Color and Shape:SolidMolecular weight:504.49PD-161570
CAS:Formula:C26H35Cl2N7OPurity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:532.51FIIN-3
CAS:FIIN-3 is an irreversible inhibitor of FGFR.Formula:C34H36Cl2N8O4Purity:97.63% - 98.92%Color and Shape:SolidMolecular weight:691.61Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:97.56% - >99.99%Color and Shape:SolidMolecular weight:498.64Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg49.00€10mg74.00€25mg122.00€50mg202.00€100mg339.00€200mg507.00€500mg800.00€1mL*10mM (DMSO)54.00€Ferulic acid sodium
CAS:Ferulic acid sodium (Sodium ferulic) is an agent used in the treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.Formula:C10H9NaO4Purity:99.58%Color and Shape:White Crystalline PowderMolecular weight:216.16PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Formula:C26H30Cl2N6O4Purity:98.65%Color and Shape:SolidMolecular weight:561.46Ref: TM-TQ0015
1mg77.00€2mg100.00€5mg166.00€10mg289.00€25mg492.00€50mg710.00€100mg973.00€1mL*10mM (DMSO)200.00€SU4984
CAS:SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).Formula:C20H19N3O2Purity:97.20%Color and Shape:SolidMolecular weight:333.38PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48
