Fibroblast Growth Factor Receptor (FGFR)
FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.
Found 170 products of "Fibroblast Growth Factor Receptor (FGFR)"
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Roblitinib
CAS:<p>Roblitinib (FGF-401), an FGFR4 inhibitor, potentially blocks tumor growth by halting cell proliferation and survival.</p>Formula:C25H30N8O4Purity:97.27% - 99%Color and Shape:SolidMolecular weight:506.56FIIN-3
CAS:<p>FIIN-3 is an irreversible inhibitor of FGFR.</p>Formula:C34H36Cl2N8O4Purity:97.63% - 98.92%Color and Shape:SolidMolecular weight:691.61PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Formula:C17H13BrN4OPurity:99.13% - 99.83%Color and Shape:SolidMolecular weight:369.22EOC317
CAS:<p>EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).</p>Formula:C27H26F5N7O3Purity:98.00% - 99.26%Color and Shape:SolidMolecular weight:591.53Lenvatinib mesylate
CAS:<p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>Formula:C22H23ClN4O7SPurity:99.03% - 99.79%Color and Shape:SolidMolecular weight:522.96Derazantinib
CAS:<p>Derazantinib (ARQ-087) is a potent, ATP-competitive, orally active tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Formula:C29H29FN4OPurity:99.71%Color and Shape:SolidMolecular weight:468.57Zoligratinib
CAS:<p>Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.</p>Formula:C20H16N6OPurity:95.28% - 99.51%Color and Shape:SolidMolecular weight:356.38KHS 101
CAS:<p>KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.</p>Formula:C18H21N5SPurity:99.63%Color and Shape:SolidMolecular weight:339.46CHIR-98014
CAS:<p>CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.</p>Formula:C20H17Cl2N9O2Purity:97.25% - 99.59%Color and Shape:SolidMolecular weight:486.31FGFR4-IN-1
CAS:<p>FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).</p>Formula:C24H27N7O5Purity:98.96%Color and Shape:SolidMolecular weight:493.52LY2874455
CAS:<p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>Formula:C21H19Cl2N5O2Purity:97.22% - 99.46%Color and Shape:SolidMolecular weight:444.31Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35S49076
CAS:<p>S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.</p>Formula:C22H22N4O4SPurity:95.35% - 97.4%Color and Shape:SolidMolecular weight:438.5FIIN-2
CAS:<p>FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.</p>Formula:C35H38N8O4Purity:97.82% - 99.65%Color and Shape:Crystalline SolidMolecular weight:634.73Erdafitinib
CAS:<p>Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.</p>Formula:C25H30N6O2Purity:97.00% - 99.07%Color and Shape:SolidMolecular weight:446.54Heparan Sulfate
CAS:<p>Heparan sulfate is a natural product, a linear polysaccharide. Heparan sulfate occurs as a proteoglycan (HSPG). Cost effective and quality assured.</p>Formula:C12H19NO20S3(monomer)Purity:98%Color and Shape:SolidMolecular weight:593.47(monomer)KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.4Gandotinib
CAS:<p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Formula:C29H34N6O4S2Purity:97.67% - 98.44%Color and Shape:SolidMolecular weight:594.75Nintedanib esylate
CAS:<p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>Formula:C31H33N5O4·C2H6O3SPurity:99.43% - 99.96%Color and Shape:SolidMolecular weight:649.76
