CymitQuimica logo
Fibroblast Growth Factor Receptor (FGFR)

Fibroblast Growth Factor Receptor (FGFR)

FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.

Found 170 products of "Fibroblast Growth Factor Receptor (FGFR)"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Infigratinib-Boc
    Targetmol
    + Info

    Infigratinib-Boc

    CAS:
    <p>Infigratinib-Boc, a derivative of the ATP-competitive pan-FGFR inhibitor Infigratinib, incorporates a Boc (t-Butyloxy carbonyl) group [1].</p>
    Formula:C29H35Cl2N7O5
    Color and Shape:Solid
    Molecular weight:632.54

    Ref: TM-T84688

  • FGFR4-IN-8
    Targetmol
    + Info

    FGFR4-IN-8

    CAS:
    <p>FGFR4-IN-8 is a selective, ATP-competitive FGFR4 inhibitor with IC50s as low as 0.25 nM, halting growth of Hep3B cells at 29 nM and showing in vivo efficacy.</p>
    Formula:C32H34Cl2FN7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:654.56

    Ref: TM-T73121

  • FGFR-IN-11
    Targetmol
    + Info

    FGFR-IN-11

    CAS:
    <p>FGFR-IN-11 (compound I-5) is an orally active, covalent inhibitor of FGFR, exhibiting IC50 values of 9.9 nM (FGFR1), 3.1 nM (FGFR2), 16 nM (FGFR3), and 1.8 nM (</p>
    Formula:C28H29ClN4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:521.01

    Ref: TM-T79257

  • Resigratinib
    Targetmol
    + Info

    Resigratinib

    CAS:
    <p>Resigratinib (KIN-3248) is an oral, irreversible pan-FGFR family protein inhibitor, covalently binds to and inhibits all four FGFR isoforms(FGFR1/2/3/4).</p>
    Formula:C26H27F2N7O3
    Purity:98.58%
    Color and Shape:Solid
    Molecular weight:523.53

    Ref: TM-T79856

  • FGFR3-IN-6
    Targetmol
    + Info

    FGFR3-IN-6

    CAS:
    <p>FGFR3-IN-6 is a potent, selective inhibitor of FGFR 3, exhibiting an IC50 value of less than 350 nM , and is utilized in cancer research [1].</p>
    Formula:C25H23FN8O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:486.5

    Ref: TM-T82405

  • FGFR3-IN-7
    Targetmol
    + Info

    FGFR3-IN-7

    CAS:
    <p>FGFR3-IN-7 is a potent, selective inhibitor of FGFR 3, demonstrating an IC50 value of less than 350 nM , and is utilized in cancer research [1].</p>
    Formula:C25H24FN9O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:485.52

    Ref: TM-T82404

  • FGFR4-IN-16
    Targetmol
    + Info

    FGFR4-IN-16

    CAS:
    <p>FGFR4-IN-16 (CY-15-2) is a covalent inhibitor targeting FGFR-4, utilized in cancer research [1].</p>
    Formula:C35H30Cl2N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:685.56

    Ref: TM-T79880

  • Irpagratinib
    Targetmol
    + Info

    Irpagratinib

    CAS:
    <p>Irpagratinib (ABSK011) is an FGFR4 antagonist with anticancer activity, inhibiting FGFR4 autophosphorylation and blocking downstream signaling pathways.</p>
    Formula:C28H32F2N6O5
    Purity:99.08% - 99.38%
    Color and Shape:Solid
    Molecular weight:570.59

    Ref: TM-T79850

  • FIIN-1
    Targetmol
    + Info

    FIIN-1

    CAS:
    <p>FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3,</p>
    Formula:C32H39Cl2N7O4
    Purity:98.75%
    Color and Shape:Solid
    Molecular weight:656.6

    Ref: TM-T37426

  • FGFR3-IN-4
    Targetmol
    + Info

    FGFR3-IN-4

    CAS:
    <p>FGFR3-IN-4 is a selective inhibitor targeting FGFR3, demonstrating an IC50 value of under 50 nM.</p>
    Formula:C26H24ClN7O
    Color and Shape:Solid
    Molecular weight:485.97

    Ref: TM-T73145

  • CymitQuimica logo
    Targetmol
    + Info

    FGFR4-IN-9

    <p>FGFR4-IN-9 is a selective inhibitor of FGFR4 (IC50: 75.3 nM) that effectively inhibits the growth and angiogenesis of hepatocellular carcinoma cells.</p>
    Formula:C24H22ClF3N4O4
    Color and Shape:Solid
    Molecular weight:522.9

    Ref: TM-T63662

  • FGFR-IN-5
    Targetmol
    + Info

    FGFR-IN-5

    CAS:
    <p>FGFR-IN-5 is a potent inhibitor of FGFR. FGFR-IN-5 has potential for research in cancer diseases.</p>
    Formula:C25H22N6O3
    Color and Shape:Solid
    Molecular weight:454.48

    Ref: TM-T62794

  • FGFR-IN-6
    Targetmol
    + Info

    FGFR-IN-6

    CAS:
    <p>FGFR-IN-6 (Compound 5) is an FGFR inhibitor.</p>
    Formula:C23H22N6O3
    Color and Shape:Solid
    Molecular weight:430.46

    Ref: TM-T62391

  • CymitQuimica logo
    Targetmol
    + Info

    FGFR4-IN-6

    <p>FGFR4-IN-6: covalent, reversible FGFR4 blocker, 5.4 nM IC50, good oral bioavailability, reduces Hep3B2.1-7 tumors in mice, low toxicity.</p>
    Formula:C31H33N7O4
    Color and Shape:Solid
    Molecular weight:567.64

    Ref: TM-T64015

  • E7090 succinate
    Targetmol
    + Info

    E7090 succinate

    CAS:
    <p>E7090 succinate inhibits FGFR1, FGFR2, and FGFR3 with IC50: 0.71, 0.50, 1.2 nM; less so FGFR4 at 120 nM.</p>
    Formula:C76H92N10O24
    Color and Shape:Solid
    Molecular weight:1529.60

    Ref: TM-T72749

  • CymitQuimica logo
    Targetmol
    + Info

    FGFR1 inhibitor-6

    <p>FGFR1 inhibitor-6, IC50: 16.31 nM, blocks cell cycle at pro-G1/G2/M and induces apoptosis.</p>
    Formula:C27H19N5O4S2
    Color and Shape:Solid
    Molecular weight:541.6

    Ref: TM-T63816

  • CEP-11981
    Targetmol
    + Info

    CEP-11981

    CAS:
    <p>CEP-11981 is an orally active TIE2/pan-VEGFR inhibitor with broad tyrosine kinase inhibitory activity, antitumour and anti-angiogenic, refractory solid tumours.</p>
    Formula:C28H27N7O
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:477.56

    Ref: TM-T68539

  • CymitQuimica logo
    Targetmol
    + Info

    FGFR4-IN-10

    <p>FGFR4-IN-10 (compound 5a) is a potent, selective FGFR4 inhibitor with IC50 of 70.7 nM, sparing FGFR1-3.</p>
    Formula:C20H19F3N6O3
    Color and Shape:Solid
    Molecular weight:448.4

    Ref: TM-T62682

  • AZ8010
    Targetmol
    + Info

    AZ8010

    CAS:
    <p>AZ8010 (AZ12908010) serves as an effective inhibitor of FGFR1-3 and exhibits antiproliferative properties, making it useful for cancer research.</p>
    Formula:C27H34N4O3
    Color and Shape:Solid
    Molecular weight:462.58

    Ref: TM-T89951

  • FGFR1 inhibitor-17
    Targetmol
    + Info

    FGFR1 inhibitor-17

    CAS:
    <p>FGFR1inhibitor-17 (Compound 92) is a potent inhibitor of FGFR1, with promising applications in cancer research.</p>
    Formula:C16H13ClN2O3
    Color and Shape:Solid
    Molecular weight:316.739

    Ref: TM-T205365