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Fibroblast Growth Factor Receptor (FGFR)

Fibroblast Growth Factor Receptor (FGFR)

FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.

Found 170 products of "Fibroblast Growth Factor Receptor (FGFR)"

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  • MAX-40279
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    MAX-40279

    CAS:
    <p>MAX-40279 is a potent, dual FLT3 kinase and FGFR kinase inhibitor. MAX-40279 has potential for acute myeloid leukemia (AML) studies.</p>
    Formula:C22H23FN6OS
    Color and Shape:Solid
    Molecular weight:438.52

    Ref: TM-T62513

  • Rogaratinib
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    Rogaratinib

    CAS:
    <p>Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR).</p>
    Formula:C23H26N6O3S
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:466.56

    Ref: TM-T16781

  • FGFR3-IN-2
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    FGFR3-IN-2

    CAS:
    <p>FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor that inhibits FGFR3 (IC50: 4.1 nM) and VEGFR2 (IC50: 570 nM).</p>
    Formula:C28H39N9O4S
    Color and Shape:Solid
    Molecular weight:597.73

    Ref: TM-T64215

  • FGFR-IN-7
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    FGFR-IN-7

    CAS:
    <p>FGFR-IN-7: Oral FGFR modulator, crosses blood-brain barrier, neuroprotective, phospholipidosis-resistant, useful for neurodegeneration study.</p>
    Formula:C16H21ClF2N4O2
    Color and Shape:Solid
    Molecular weight:374.81

    Ref: TM-T61528

  • ARQ 069
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    ARQ 069

    CAS:
    <p>ARQ 069 inhibits FGFR2 phosphorylation concentration-dependently (IC50: 9.7 µM), without affecting β-actin. Preferentially binds inactive FGFR1/2.</p>
    Formula:C18H15N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:273.33

    Ref: TM-T10372

  • TG 100801 Hydrochloride
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    TG 100801 Hydrochloride

    CAS:
    <p>TG 100801: prodrug for macular degeneration. TG 100572: inhibits kinases (VEGFRs, FGFRs, PDGFRβ, Src family), with varying IC50s.</p>
    Formula:C33H31Cl2N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:616.54

    Ref: TM-T13157L

  • FGFR2-IN-1
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    FGFR2-IN-1

    CAS:
    <p>FGFR2-IN-1 is an FGFR inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used to study FGFR2-associated cancers.</p>
    Formula:C22H19N3O2
    Purity:98.71%
    Color and Shape:Solid
    Molecular weight:357.41

    Ref: TM-T61304

  • CP-547632 hydrochloride
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    CP-547632 hydrochloride

    CAS:
    <p>CP-547632 hydrochloride: oral VEGFR-2/FGF inhibitor (IC50: 11/9 nM), well-tolerated, antitumor.</p>
    Formula:C20H25BrClF2N5O3S
    Color and Shape:Solid
    Molecular weight:568.86

    Ref: TM-T10870

  • CAY10583
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    CAY10583

    CAS:
    <p>CAY10583 is a selective BLT2 agonist that increases TGF-β1 and bFGF, promotes keratinocyte migration, accelerates wound healing in diabetic mice.</p>
    Formula:C25H25NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.47

    Ref: TM-T26958

  • MAX-40279 hemiadipate
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    MAX-40279 hemiadipate

    CAS:
    <p>MAX-40279 hemiadipate: Potent FLT3/FGFR inhibitor; potential in AML treatment. (Patent WO2021180032A1)</p>
    Formula:C50H56F2N12O6S2
    Color and Shape:Solid
    Molecular weight:1023.19

    Ref: TM-T64129

  • FGFR2-IN-2
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    FGFR2-IN-2

    CAS:
    <p>FGFR2-IN-2 is a specific FGFR2 inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used in the study of cancer and cardiovascular disease.</p>
    Formula:C23H22N4O
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:370.45

    Ref: TM-T61473

  • TG 100572
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    TG 100572

    CAS:
    <p>TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2</p>
    Formula:C26H26ClN5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:475.97

    Ref: TM-T13156

  • Infigratinib phosphate
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    Infigratinib phosphate

    CAS:
    <p>Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and</p>
    Formula:C26H34Cl2N7O7P
    Purity:99.24% - 99.6%
    Color and Shape:Solid
    Molecular weight:658.47

    Ref: TM-T16364

  • PP58
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    PP58

    CAS:
    <p>PP58 is an inhibitor of PDGFR, FGFR and Src family.</p>
    Formula:C22H19Cl2N5O2
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:456.32

    Ref: TM-T13824

  • FGFR-IN-2
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    FGFR-IN-2

    CAS:
    <p>FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).</p>
    Formula:C25H30N6O2
    Color and Shape:Solid
    Molecular weight:446.54

    Ref: TM-T62653

  • TG 100572 Hydrochloride
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    TG 100572 Hydrochloride

    CAS:
    <p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>
    Formula:C26H27Cl2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:512.43

    Ref: TM-T13156L

  • Sulfatinib
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    Sulfatinib

    CAS:
    <p>Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to</p>
    Formula:C24H28N6O3S
    Purity:99.21% - >99.99%
    Color and Shape:Solid
    Molecular weight:480.58

    Ref: TM-T4075

  • FGFR-IN-4
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    FGFR-IN-4

    CAS:
    <p>FGFR-IN-4 is a potent inhibitor of FGFR. FGFR-IN-4 has potential for cancer disease studies.</p>
    Formula:C24H21N7O2
    Color and Shape:Solid
    Molecular weight:439.47

    Ref: TM-T62522

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    SNIPER(TACC3)-11

    CAS:
    <p>SNIPER(TACC3)-11 is a powerful FGFR3-TACC3 protein degrader, reducing its amount and hindering FGFR3-TACC3+ cancer cell growth.</p>
    Formula:C51H66N10O7S2
    Color and Shape:Solid
    Molecular weight:995.26

    Ref: TM-T74462

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    CP-547632 TFA

    CAS:
    <p>CP-547632 TFA, an oral VEGFR-2 and FGF inhibitor, IC50: VEGFR-2 at 11 nM, FGF at 9 nM, shows antitumor activity.</p>
    Formula:C22H25BrF5N5O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:646.43

    Ref: TM-T74000