Fibroblast Growth Factor Receptor (FGFR)
FGFR inhibitors are targeted therapies that block the activity of fibroblast growth factor receptors (FGFRs), which are involved in cell proliferation, differentiation, and angiogenesis. FGFR signaling contributes to the formation of new blood vessels in tumors, promoting their growth and survival. Inhibiting FGFR can therefore reduce angiogenesis and tumor progression. At CymitQuimica, we provide a range of high-quality FGFR inhibitors to support your research in cancer, developmental biology, and angiogenesis.
Found 180 products of "Fibroblast Growth Factor Receptor (FGFR)"
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MAX-40279 hemifumarate
CAS:MAX-40279 hemifumarate inhibits FLT3 and FGFR kinases, showing promise for AML treatment.Formula:C48H50F2N12O6S2Color and Shape:SolidMolecular weight:993.12ARQ 069
CAS:ARQ 069 inhibits FGFR2 phosphorylation concentration-dependently (IC50: 9.7 µM), without affecting β-actin. Preferentially binds inactive FGFR1/2.Formula:C18H15N3Purity:98%Color and Shape:SolidMolecular weight:273.33FGFR3-IN-2
CAS:FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor that inhibits FGFR3 (IC50: 4.1 nM) and VEGFR2 (IC50: 570 nM).Formula:C28H39N9O4SColor and Shape:SolidMolecular weight:597.73Rogaratinib
CAS:Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR).Formula:C23H26N6O3SPurity:99.54%Color and Shape:SolidMolecular weight:466.56SSR128129E free acid
CAS:SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM for FGFR1).Formula:C18H16N2O4Purity:98%Color and Shape:SolidMolecular weight:324.33FGFR-IN-9
FGFR-IN-9: oral FGFR inhibitor, IC50: 17.1 nM (FGFR4 WT), 29.6 (FGFR3), 30.7 (V550L), 46.7 (FGFR2), 64.3 nM (FGFR1).Formula:C25H28N6O3SColor and Shape:SolidMolecular weight:492.59FGFR-IN-3
CAS:FGFR-IN-3: potent, oral FGFR modulator, BBB-penetrating, neuroprotective, potential in neurodegeneration study.Formula:C18H27F2N5O2Color and Shape:SolidMolecular weight:383.44Derazantinib Racemate
CAS:Derazantinib Racemate is an oral ATP competitive kinase inhibitor targeting FGFR1/2/3 (IC50s: 4.5/1.8/4.5 nM).Formula:C29H29FN4OPurity:98%Color and Shape:SolidMolecular weight:468.57SUN13837
CAS:SUN13837, an oral FGFR modulator, crosses the BBB and shows neuroprotective promise.Formula:C21H29N5O2Color and Shape:SolidMolecular weight:383.49FGFR3-IN-1
CAS:FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor that inhibits FGFR1 (IC50: 40 nM), FGFR2 (IC50: 5.1 nM) and FGFR3 (IC50: 12 nM).Formula:C28H39N9O3SColor and Shape:SolidMolecular weight:581.73FGFR-IN-7
CAS:FGFR-IN-7: Oral FGFR modulator, crosses blood-brain barrier, neuroprotective, phospholipidosis-resistant, useful for neurodegeneration study.Formula:C16H21ClF2N4O2Color and Shape:SolidMolecular weight:374.81FIIN-4
CAS:FIIN-4 is a covalent inhibitor of FGFR and can be used in studies about metastatic breast cancer.Formula:C35H38N8O4Purity:99.99%Color and Shape:SolidMolecular weight:634.73TG 100801 Hydrochloride
CAS:TG 100801: prodrug for macular degeneration. TG 100572: inhibits kinases (VEGFRs, FGFRs, PDGFRβ, Src family), with varying IC50s.Formula:C33H31Cl2N5O3Purity:98%Color and Shape:SolidMolecular weight:616.54FGFR4-IN-11
CAS:FGFR4-IN-11: selective, covalent FGFR4 inhibitor; IC50=2.1 nM; blocks FGF19 pathway; anticancer.Formula:C29H29N5O5Color and Shape:SolidMolecular weight:527.57Infigratinib phosphate
CAS:Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, andFormula:C26H34Cl2N7O7PPurity:99.24% - 99.6%Color and Shape:SolidMolecular weight:658.47MAX-40279 hydrochloride
CAS:MAX-40279 HCl: potent FLT3/FGFR inhibitor; potential in AML research.Formula:C22H24ClFN6OSColor and Shape:SolidMolecular weight:474.98FGFR3-IN-5
CAS:FGFR3-IN-5: potent, selective FGFR3 inhibitor. IC50: 3 nM FGFR3, 44 nM FGFR2, 289 nM FGFR1. For cancer research.Formula:C24H24FN7O3Color and Shape:SolidMolecular weight:477.49CAY10583
CAS:CAY10583 is a selective BLT2 agonist that increases TGF-β1 and bFGF, promotes keratinocyte migration, accelerates wound healing in diabetic mice.Formula:C25H25NO3Purity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:387.47TYRA-200
CAS:TYRA-200, Oral FGFR1/2/3 inhibitor, induces tumor regression in wild-type/mutant FGFR2 models, for intrahepatic cholangiocarcinoma.Formula:C23H24FN7O2Color and Shape:SolidMolecular weight:449.48Atrinositol
CAS:Atrinositol improves energy homeostasis in a mouse model of pancreatic cancer.Formula:C6H15O15P3Color and Shape:SolidMolecular weight:420.1
