ALK
ALK inhibitors are compounds that specifically target and inhibit Anaplastic Lymphoma Kinase (ALK), a receptor tyrosine kinase involved in the development and progression of certain cancers, including non-small cell lung cancer and neuroblastoma. By inhibiting ALK, these compounds block signaling pathways that promote tumor cell growth and survival. At CymitQuimica, we offer ALK inhibitors to support your research in oncology, targeted cancer therapies, and signal transduction.
Found 137 products of "ALK"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Lorlatinib
CAS:Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogeneFormula:C21H19FN6O2Purity:99.77% - 99.95%Color and Shape:SolidMolecular weight:406.41Ref: TM-T3061
1mg34.00€2mg42.00€5mg60.00€10mg89.00€25mg137.00€50mg212.00€100mg374.00€1mL*10mM (DMSO)66.00€Alectinib
CAS:Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.Formula:C30H34N4O2Purity:98% - 99.38%Color and Shape:SolidMolecular weight:482.62Ref: TM-T1936
2mg47.00€5mg69.00€10mg87.00€50mg105.00€100mg168.00€200mg259.00€500mg437.00€1mL*10mM (DMSO)73.00€SM 16
CAS:SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).Formula:C25H26N4O3Purity:99.72%Color and Shape:SolidMolecular weight:430.5CEP-37440
CAS:CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).Formula:C30H38ClN7O3Purity:98.86% - 99.98%Color and Shape:SolidMolecular weight:580.12GSK1838705A
CAS:GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.Formula:C27H29FN8O3Purity:98.89% - >99.99%Color and Shape:SolidMolecular weight:532.57Crizotinib
CAS:Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formula:C21H22Cl2FN5OPurity:99% - 99.87%Color and Shape:SolidMolecular weight:450.34Ref: TM-T1661
2mgTo inquire5mg33.00€10mg49.00€25mg55.00€50mg64.00€100mg88.00€500mg147.00€1mL*10mM (DMSO)50.00€A 83-01
CAS:A 83-01 (ALK5 Inhibitor IV) is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7.Formula:C25H19N5SPurity:97% - 98.2%Color and Shape:SolidMolecular weight:421.52LDN-214117
CAS:LDN-214117 is a potent and selective ALK2 inhibitor.
Formula:C25H29N3O3Purity:98% - 99.82%Color and Shape:SolidMolecular weight:419.52DMH-1
CAS:DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.
Formula:C24H20N4OPurity:98% - 99.92%Color and Shape:SolidMolecular weight:380.44Brigatinib
CAS:Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
Formula:C29H39ClN7O2PPurity:97.18% - >99.99%Color and Shape:SolidMolecular weight:584.09LDN193189
CAS:LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.Formula:C25H22N6Purity:98% - 99.86%Color and Shape:SolidMolecular weight:406.48Crizotinib acetate
CAS:Crizotinib is an oral c-met/HGFR tyrosine kinase inhibitor with potential cancer-fighting properties.Formula:C23H26Cl2FN5O3Color and Shape:SolidMolecular weight:510.39ALK kinase inhibitor-1
CAS:SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.Formula:C28H32FN5O3SPurity:99.84%Color and Shape:SolidMolecular weight:537.65Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formula:C21H23Cl3FN5OPurity:98.73% - 98.87%Color and Shape:SolidMolecular weight:486.8Ref: TM-T8399
5mg34.00€10mg50.00€25mg78.00€50mg94.00€100mg131.00€200mg162.00€500mg215.00€1mL*10mM (DMSO)56.00€AZD-3463
CAS:AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formula:C24H25ClN6OPurity:99.13%Color and Shape:SolidMolecular weight:448.95Vactosertib
CAS:Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.Formula:C22H18FN7Purity:98.85% - 99.81%Color and Shape:SolidMolecular weight:399.42GW788388
CAS:GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
Formula:C25H23N5O2Purity:98.03% - 99.58%Color and Shape:SolidMolecular weight:425.48RepSox
CAS:RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM).Formula:C17H13N5Purity:98.8% - 99.73%Color and Shape:SolidMolecular weight:287.32Ref: TM-T6337
1mg34.00€2mg46.00€5mg63.00€10mg80.00€25mg116.00€50mg169.00€100mg241.00€500mg597.00€1mL*10mM (DMSO)69.00€CH5424802 analog
CAS:CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.Formula:C28H30N4O2Purity:98.96%Color and Shape:SolidMolecular weight:454.56Ref: TM-T9224
1mg124.00€5mg271.00€10mg408.00€25mg672.00€50mg945.00€100mg1,279.00€1mL*10mM (DMSO)324.00€A 77-01
CAS:A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.Formula:C18H14N4Purity:98.82% - ≥95%Color and Shape:SolidMolecular weight:286.33Ref: TM-T2098
1mg40.00€2mg52.00€5mg86.00€10mg118.00€25mg200.00€50mg280.00€100mg394.00€200mg580.00€1mL*10mM (DMSO)95.00€
