c-Met/HGFR
c-Met/HGFR inhibitors target the Hepatocyte Growth Factor Receptor (c-Met), a tyrosine kinase involved in cellular processes such as growth, motility, and morphogenesis. c-Met signaling is implicated in cancer progression, metastasis, and resistance to therapies. Inhibiting c-Met can disrupt tumor growth and spread, making these inhibitors valuable in cancer research. At CymitQuimica, we offer c-Met/HGFR inhibitors to support your research in oncology, metastasis, and targeted cancer therapies.
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Bozitinib
CAS:1440964-89-5
Bozitinib (PLB-1001) (PLB-1001) is a highly selective inhibitor of the c-MET kinase with blood-brain barrier …
Formula:
C20H15F3N8
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
424.38
Ref: TM-T10585
| 1mg | 104.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 346.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 884.00 € | ||
| 100mg | 1,234.00 € | ||
| 1mL*10mM (DMSO) | 235.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
JNJ-38877618
CAS:943540-74-7
JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and …
Formula:
C20H12F2N6
Purity:
98.84% - 99.52%
Color and Shape:
Solid
Molecular weight:
374.35
Ref: TM-T15617
| 1mg | 63.00 € | ||
| 2mg | 88.00 € | ||
| 5mg | 137.00 € | ||
| 10mg | 211.00 € | ||
| 25mg | 424.00 € | ||
| 50mg | 625.00 € | ||
| 100mg | 891.00 € | ||
| 500mg | 1,746.00 € | ||
| 1mL*10mM (DMSO) | 153.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Pamufetinib
CAS:1190836-34-0
Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase.
Formula:
C27H23FN4O4S
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
518.56
Ref: TM-T13108
| 1mg | 50.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 251.00 € | ||
| 50mg | 368.00 € | ||
| 100mg | 524.00 € | ||
| 200mg | 713.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CSF1R-IN-2
CAS:2271119-26-5
CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and …
Formula:
C20H20FN7O2
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
409.42
Ref: TM-T13194
| 1mg | 44.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 487.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
c-Met inhibitor 1
CAS:1357072-61-7
c-Met inhibitor 1 is a c-Met receptor signaling pathway inhibitor, used for the treatment of …
Formula:
C17H14N8S
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
362.41
Ref: TM-T10655
| 1mg | 83.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 233.00 € | ||
| 25mg | 388.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 820.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MET/PDGFRA-IN-1
MET/PDGFRA-IN-1 (compound 8c) serves as an inhibitor of MET and PDGFRA proteins, displaying an IC50 …
Formula:
C26H23N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
449.51
Ref: TM-T78843
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
PF-04217903 phenolsulfonate
CAS:1159490-85-3
PF-04217903 phenolsulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for …
Formula:
C25H22N8O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
546.56
Ref: TM-T12418
| 25mg | 1,432.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Rilotumumab
CAS:872514-65-3
Rilotumumab (AMG 102) is an HGF-targeting antibody, inhibits HGF/MET signaling, and is used for CRPC …
Purity:
SDS-PAGE:95% SEC-HPLC:97.51%
Color and Shape:
Liquid
Molecular weight:
145.2 kDa
Ref: TM-T76758
| 1mg | 237.00 € | ||
| 5mg | 620.00 € | ||
| 10mg | 993.00 € | ||
| 25mg | 1,476.00 € | ||
| 50mg | 1,977.00 € | ||
| 100mg | 2,673.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Emibetuzumab
CAS:1365287-97-3
Emibetuzumab: potent humanized MET antibody, antitumor, inhibits HGF/MET pathways, for advanced prostate cancer research.
Purity:
SDS-PAGE:96.2%;SEC-HPLC:98.8%
Color and Shape:
Liquid
Molecular weight:
143.74 kDa
Ref: TM-T76743
| 1mg | 142.00 € | ||
| 5mg | 416.00 € | ||
| 10mg | 662.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
LMTK3-IN-1
CAS:2764850-23-7
Lmtk3-in-1 is a potent ATP-competitive lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM) inhibitor that degrades …
Formula:
C18H11F3N4O
Purity:
100%
Color and Shape:
Soild
Molecular weight:
356.3
Ref: TM-T77620
| 1mg | 52.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 609.00 € | ||
| 500mg | 1,263.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Onartuzumab
CAS:1133766-06-9
Onartuzumab (MetMAb) is a humanized monoclonal antibody targeting c-MET, with antitumor effects by blocking HGF …
Purity:
97.3%
Color and Shape:
Liquid
Molecular weight:
146.99 kDa
Ref: TM-T76780
| 1mg | 422.00 € | ||
| 5mg | 1,744.00 € | ||
| 10mg | 2,335.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Telisotuzumab
CAS:1781223-80-0
Telisotuzumab(ABT-700) is a humanized recombinant antibody targeting the therapeutic hepatocyte growth factor receptor (MET) with …
Purity:
SDS-PAGE:96.4%;SEC-HPLC:98.5%
Color and Shape:
Liquid
Molecular weight:
145.50 kDa
Ref: TM-T77437
| 1mg | 346.00 € | ||
| 5mg | 866.00 € | ||
| 10mg | 1,389.00 € | ||
| 25mg | 2,032.00 € | ||
| 50mg | 2,767.00 € | ||
| 100mg | 3,647.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
c-Met-IN-17
c-Met-IN-17 is a potent inhibitor of c-Met kinase, demonstrating an IC50 of 0.031 μM, and …
Formula:
C21H15FN4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
374.37
Ref: TM-T79142
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
C-Met inhibitor D9
CAS:299405-67-7
C-Met inhibitor D9 is a c-Met kinase inhibitor.
Formula:
C17H15N3O2
Purity:
97%
Color and Shape:
Liquid
Molecular weight:
293.32
Ref: TM-T67859
| 1mg | 182.00 € | ||
| 5mg | 418.00 € | ||
| 10mg | 614.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,281.00 € | ||
| 100mg | 1,754.00 € | ||
| 500mg | 3,511.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
c-Met-IN-18
C-Met-IN-18, an ATP-competitive type-III inhibitor, targets both wild-type (WT) and D1228V mutant c-MET with IC50 …
Formula:
C21H15FN4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
374.37
Ref: TM-T78934
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Antitumor agent-111
Antitumor Agent-111 (Compound 46), a c-Met kinase inhibitor (IC50 = 46 nM), exhibits both antitumor …
Formula:
C34H29ClF2N6O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
675.08
Ref: TM-T79466
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
c-Met-IN-19
c-Met-IN-19 (Compound 21j) is a potent c-Met inhibitor with an IC50 of 1.99 nM and …
Formula:
C34H37Cl2FN4O7S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
735.65
Ref: TM-T79715
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Fosgonimeton acetate
Fosgonimeton acetate is an agonist of hepatocyte growth factor (HGF).
Formula:
C29H49N4O10P
Purity:
97.05%
Color and Shape:
Liquid
Molecular weight:
644.69
Ref: TM-T39507L
| 1mg | 112.00 € | ||
| 2mg | 155.00 € | ||
| 5mg | 229.00 € | ||
| 10mg | 340.00 € | ||
| 25mg | 543.00 € | ||
| 50mg | 730.00 € | ||
| 100mg | 979.00 € | ||
| 200mg | 1,309.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
1D228
1D228, a c-Met/TRK inhibitor with antitumor properties, suppresses cyclin D1 to precipitate G0/G1 arrest, thereby …
Purity:
98%
Ref: TM-T83433
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Davutamig
CAS:2648058-48-2
Davutamig (REGN-5093) is a humanized IgG4-kappa, anti-MET monoclonal antibody that binds to two distinct, nonoverlapping …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T82608
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
