c-Met/HGFR
c-Met/HGFR inhibitors target the Hepatocyte Growth Factor Receptor (c-Met), a tyrosine kinase involved in cellular processes such as growth, motility, and morphogenesis. c-Met signaling is implicated in cancer progression, metastasis, and resistance to therapies. Inhibiting c-Met can disrupt tumor growth and spread, making these inhibitors valuable in cancer research. At CymitQuimica, we offer c-Met/HGFR inhibitors to support your research in oncology, metastasis, and targeted cancer therapies.
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Tyrosine kinase inhibitor
CAS:1021950-26-4
Tyrosine kinase inhibitor is a tyrosine kinase inhibitor used in combination with fragmenting aromatic nitrogen …
Formula:
C31H31FN6O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
586.61
Ref: TM-T17184
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 14 Apr 2025
Fosgonimeton acetate
Fosgonimeton acetate is an agonist of hepatocyte growth factor (HGF).
Formula:
C29H49N4O10P
Purity:
97.05%
Color and Shape:
Liquid
Molecular weight:
644.69
Ref: TM-T39507L
| 1mg | 116.00 € | ||
| 2mg | 160.00 € | ||
| 5mg | 238.00 € | ||
| 10mg | 353.00 € | ||
| 25mg | 563.00 € | ||
| 50mg | 758.00 € | ||
| 100mg | 1,017.00 € | ||
| 200mg | 1,359.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
1D228
1D228, a c-Met/TRK inhibitor with antitumor properties, suppresses cyclin D1 to precipitate G0/G1 arrest, thereby …
Purity:
98%
Ref: TM-T83433
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 14 Apr 2025
MET/PDGFRA-IN-2
MET/PDGFRA-IN-2 (compound 8h) serves as an inhibitor of MET and PDGFRA proteins, promoting apoptosis in …
Formula:
C29H29N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
491.59
Ref: TM-T78844
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 14 Apr 2025
Umikibart
Umikibart is a humanized IgG4κ antibody targeting HGF, with the corresponding isotype control being HumanIgG4(S228P) …
Ref: TM-T9901A-415
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 14 Apr 2025
Antitumor agent-111
Antitumor Agent-111 (Compound 46), a c-Met kinase inhibitor (IC50 = 46 nM), exhibits both antitumor …
Formula:
C34H29ClF2N6O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
675.08
Ref: TM-T79466
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 14 Apr 2025
SYN1143
CAS:913376-84-8
SYN1143 (AMG-1) strongly inhibits RON & c-Met with IC50s: 9 & 4 nmol/L.
Formula:
C31H29FN4O5
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
556.58
Ref: TM-T8409
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 170.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
PF-04217903 methanesulfonate
CAS:956906-93-7
PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for …
Formula:
C20H20N8O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
468.49
Ref: TM-T12417
| 2mg | 54.00 € | ||
| 5mg | 85.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
BMS-794833
CAS:1174046-72-0
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.
Formula:
C23H15ClF2N4O3
Purity:
98% - 99.69%
Color and Shape:
Solid
Molecular weight:
468.84
Ref: TM-T2419
| 1mg | 42.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 772.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Tepotinib hydrochloride(1 : x)
CAS:1103508-80-0
Tepotinib hydrochloride(1 : x) is an orally bioavailable, mesenchymal-epithelial transition (MET) TKI developed mainly for …
Formula:
C29H29ClN6O2
Purity:
99.81%
Color and Shape:
Liquid
Molecular weight:
529.04
Ref: TM-T9601
| 1mg | 145.00 € | ||
| 5mg | 319.00 € | ||
| 10mg | 472.00 € | ||
| 25mg | 753.00 € | ||
| 50mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 401.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
XL092
CAS:2367004-54-2
XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and …
Formula:
C29H25FN4O5
Purity:
98.60%
Color and Shape:
Solid
Molecular weight:
528.53
Ref: TM-T9052
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 134.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 353.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SCR-1481B1
CAS:1174161-86-4
SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has …
Formula:
C32H40ClF2N6O13P
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
821.12
Ref: TM-T5349
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Amuvatinib
CAS:850879-09-3
Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.
Formula:
C23H21N5O3S
Purity:
98.48% - 99.54%
Color and Shape:
Solid
Molecular weight:
447.51
Ref: TM-T2516
| 1mg | 52.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 261.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 528.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
PHA-665752
CAS:477575-56-7
PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for …
Formula:
C32H34Cl2N4O4S
Purity:
97.01% - 99.35%
Color and Shape:
Solid
Molecular weight:
641.61
Ref: TM-T6128
| 5mg | 65.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 279.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Capmatinib
CAS:1029712-80-8
Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.
Formula:
C23H17FN6O
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
412.42
Ref: TM-T1963
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 131.00 € | ||
| 200mg | 166.00 € | ||
| 500mg | 269.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Crizotinib hydrochloride
CAS:1415560-69-8
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of …
Formula:
C21H23Cl3FN5O
Purity:
98.87%
Color and Shape:
Solid
Molecular weight:
486.8
Ref: TM-T8399
| 5mg | 37.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 99.00 € | ||
| 100mg | 138.00 € | ||
| 200mg | 171.00 € | ||
| 500mg | 227.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SAR125884 hydrochlorid (1116743-46-4(free base))
CAS:1116743-46-4
SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 …
Formula:
C25H23FN8O2S2·HCl
Purity:
97.95%
Color and Shape:
Solid
Molecular weight:
587
Ref: TM-T5677
| 1mg | 38.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 279.00 € | ||
| 100mg | 395.00 € | ||
| 200mg | 567.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
JNJ-38877605
CAS:943540-75-8
JNJ-38877605 is an ATP-competitive c-Met inhibitor (IC50: 4 nM), 600-fold selective for c-Met than 200 …
Formula:
C19H13F2N7
Purity:
97.04% - 98.27%
Color and Shape:
Solid
Molecular weight:
377.35
Ref: TM-T6095
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 145.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Merestinib
CAS:1206799-15-6
Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 …
Formula:
C30H22F2N6O3
Purity:
95% - 99.56%
Color and Shape:
Solid
Molecular weight:
552.53
Ref: TM-T3455
| 1mg | 49.00 € | ||
| 2mg | 70.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 254.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 605.00 € | ||
| 500mg | 1,264.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
MGCD-265 analog
CAS:875337-44-3
Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM …
Formula:
C26H20FN5O2S2
Purity:
98.06% - 98.68%
Color and Shape:
Solid
Molecular weight:
517.6
Ref: TM-T6351
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
