c-Met/HGFR
c-Met/HGFR inhibitors target the Hepatocyte Growth Factor Receptor (c-Met), a tyrosine kinase involved in cellular processes such as growth, motility, and morphogenesis. c-Met signaling is implicated in cancer progression, metastasis, and resistance to therapies. Inhibiting c-Met can disrupt tumor growth and spread, making these inhibitors valuable in cancer research. At CymitQuimica, we offer c-Met/HGFR inhibitors to support your research in oncology, metastasis, and targeted cancer therapies.
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Foretinib
CAS:849217-64-7
Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 …
Formula:
C34H34F2N4O6
Purity:
98.07% - 99.7%
Color and Shape:
Solid
Molecular weight:
632.65
Ref: TM-T3113
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 349.00 € | ||
| 500mg | 829.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Ningetinib
CAS:1394820-69-9
Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 …
Formula:
C31H29FN4O5
Purity:
99.77% - 99.95%
Color and Shape:
Solid
Molecular weight:
556.58
Ref: TM-TQ0021
| 2mg | 49.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 548.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Tivantinib
CAS:905854-02-6
Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic …
Formula:
C23H19N3O2
Purity:
98% - 99.41%
Color and Shape:
Solid
Molecular weight:
369.42
Ref: TM-T6117
| 5mg | 51.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 341.00 € | ||
| 200mg | 555.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
NPS-1034
CAS:1221713-92-3
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
Formula:
C31H23F2N5O3
Purity:
97.86%
Color and Shape:
Solid
Molecular weight:
551.54
Ref: TM-T6907
| 1mg | 38.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 98.00 € | ||
| 25mg | 195.00 € | ||
| 50mg | 322.00 € | ||
| 100mg | 451.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
CEP-40783
CAS:1437321-24-8
CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It …
Formula:
C31H26F2N4O6
Purity:
99.45% - 99.64%
Color and Shape:
Solid
Molecular weight:
588.56
Ref: TM-T4426
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 203.00 € | ||
| 100mg | 293.00 € | ||
| 200mg | 423.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Ningetinib Tosylate
CAS:1394820-77-9
Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and …
Formula:
C38H37FN4O8S
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
728.79
Ref: TM-TQ0041
| 5mg | 47.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Crizotinib
CAS:877399-52-5
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and …
Formula:
C21H22Cl2FN5O
Purity:
99% - 99.87%
Color and Shape:
Solid
Molecular weight:
450.34
Ref: TM-T1661
| 10mg | 55.00 € | ||
| 25mg | 64.00 € | ||
| 50mg | 73.00 € | ||
| 100mg | 97.00 € | ||
| 200mg | 100.00 € | ||
| 500mg | 158.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
AMG-208
CAS:1002304-34-8
AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
Formula:
C22H17N5O2
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
383.4
Ref: TM-T6260
| 2mg | 38.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 246.00 € | ||
| 100mg | 355.00 € | ||
| 200mg | 506.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
S49076
CAS:1265965-22-7
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of …
Formula:
C22H22N4O4S
Purity:
95.35% - 97.4%
Color and Shape:
Solid
Molecular weight:
438.5
Ref: TM-T3274
| 1mg | 46.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 549.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
(Z)-Semaxinib
CAS:194413-58-6
(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective …
Formula:
C15H14N2O
Purity:
96.09% - ≥95%
Color and Shape:
Solid
Molecular weight:
238.28
Ref: TM-T2496
| 1mg | 56.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 325.00 € | ||
| 50mg | 559.00 € | ||
| 100mg | 680.00 € | ||
| 200mg | 926.00 € | ||
| 1mL*10mM (DMSO) | 143.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Cabozantinib hydrochloride
CAS:1817759-42-4
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, …
Formula:
C28H25ClFN3O5
Purity:
97.09%
Color and Shape:
Solid
Molecular weight:
537.96
Ref: TM-T5164
| 1mg | 43.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 242.00 € | ||
| 100mg | 341.00 € | ||
| 200mg | 555.00 € | ||
| 500mg | 888.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
BAY-474
CAS:1033767-86-0
BAY-474 is an inhibitor of tyrosine-protein kinase c-Met. It acts as an epigenetics probe
Formula:
C17H15N5
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
289.33
Ref: TM-T7900
| 1mg | 49.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 164.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 428.00 € | ||
| 100mg | 598.00 € | ||
| 200mg | 805.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Afatinib
CAS:850140-72-6
Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and …
Formula:
C24H25ClFN5O3
Purity:
97.56% - 99.9%
Color and Shape:
Off-White Solid
Molecular weight:
485.94
Ref: TM-T21312
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 142.00 € | ||
| 200mg | 174.00 € | ||
| 500mg | 294.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
SU11274
CAS:658084-23-2
SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects …
Formula:
C28H30ClN5O4S
Purity:
98.62% - 99.44%
Color and Shape:
Orange Powder
Molecular weight:
568.09
Ref: TM-T6154
| 1mg | 46.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 455.00 € | ||
| 100mg | 673.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
AMG-458
CAS:913376-83-7
AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met …
Formula:
C30H29N5O5
Purity:
98.39% - 99.77%
Color and Shape:
Solid
Molecular weight:
539.58
Ref: TM-T6378
| 1mg | 43.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 272.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 550.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Glesatinib hydrochloride
CAS:1123838-51-6
Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO.
Formula:
C31H28ClF2N5O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
656.16
Ref: TM-T15383
| 25mg | 885.00 € | ||
| 50mg | 1,160.00 € | ||
| 100mg | 1,861.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
Glesatinib
CAS:936694-12-1
Glesatinib is an orally active and potent dual inhibitor of MET/SMO.
Formula:
C31H27F2N5O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
619.7
Ref: TM-T15384
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
SAR125844
CAS:1116743-46-4
SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for …
Formula:
C25H23FN8O2S2
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
550.63
Ref: TM-T5467
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 224.00 € | ||
| 50mg | 356.00 € | ||
| 100mg | 580.00 € | ||
| 200mg | 822.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
Tyrosine kinase-IN-6
CAS:2377507-01-0
Tyrosine kinase-IN-6 is a potent inhibitor of RON splice variants, demonstrating significant anticancer and antineoplastic …
Formula:
C37H31F2N5O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
695.73
Ref: TM-T79612
| 25mg | 1,688.00 € | ||
| 50mg | 2,225.00 € | ||
| 100mg | 2,897.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Terevalefim
CAS:1070881-42-3
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
Formula:
C9H8N2S
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
176.24
Ref: TM-T37596
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 207.00 € | ||
| 25mg | 360.00 € | ||
| 50mg | 529.00 € | ||
| 100mg | 737.00 € | ||
| 500mg | 1,504.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
