c-Met/HGFR
c-Met/HGFR inhibitors target the Hepatocyte Growth Factor Receptor (c-Met), a tyrosine kinase involved in cellular processes such as growth, motility, and morphogenesis. c-Met signaling is implicated in cancer progression, metastasis, and resistance to therapies. Inhibiting c-Met can disrupt tumor growth and spread, making these inhibitors valuable in cancer research. At CymitQuimica, we offer c-Met/HGFR inhibitors to support your research in oncology, metastasis, and targeted cancer therapies.
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Foretinib
CAS:849217-64-7
Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 …
Formula:
C34H34F2N4O6
Purity:
98.07% - 99.68%
Color and Shape:
Solid
Molecular weight:
632.65
Ref: TM-T3113
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 354.00 € | ||
| 500mg | 848.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Ningetinib
CAS:1394820-69-9
Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 …
Formula:
C31H29FN4O5
Purity:
99.77% - 99.95%
Color and Shape:
Solid
Molecular weight:
556.58
Ref: TM-TQ0021
| 2mg | 49.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Tivantinib
CAS:905854-02-6
Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic …
Formula:
C23H19N3O2
Purity:
98% - 99.41%
Color and Shape:
Solid
Molecular weight:
369.42
Ref: TM-T6117
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 349.00 € | ||
| 200mg | 567.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
NPS-1034
CAS:1221713-92-3
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
Formula:
C31H23F2N5O3
Purity:
98.48%
Color and Shape:
Solid
Molecular weight:
551.54
Ref: TM-T6907
| 1mg | 38.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 197.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
CEP-40783
CAS:1437321-24-8
CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It …
Formula:
C31H26F2N4O6
Purity:
99.45% - 99.64%
Color and Shape:
Solid
Molecular weight:
588.56
Ref: TM-T4426
| 5mg | 50.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 304.00 € | ||
| 200mg | 437.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Ningetinib Tosylate
CAS:1394820-77-9
Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and …
Formula:
C38H37FN4O8S
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
728.79
Ref: TM-TQ0041
| 5mg | 48.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 363.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Crizotinib
CAS:877399-52-5
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and …
Formula:
C21H22Cl2FN5O
Purity:
99% - 99.87%
Color and Shape:
Solid
Molecular weight:
450.34
Ref: TM-T1661
| 10mg | 50.00 € | ||
| 25mg | 60.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 93.00 € | ||
| 200mg | 97.00 € | ||
| 500mg | 156.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AMG-208
CAS:1002304-34-8
AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
Formula:
C22H17N5O2
Purity:
98.56%
Color and Shape:
Solid
Molecular weight:
383.4
Ref: TM-T6260
| 2mg | 39.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 369.00 € | ||
| 200mg | 525.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
S49076
CAS:1265965-22-7
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of …
Formula:
C22H22N4O4S
Purity:
95.35% - 97.4%
Color and Shape:
Solid
Molecular weight:
438.5
Ref: TM-T3274
| 1mg | 47.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 558.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
DS-1205
CAS:1855860-24-0
DS-1205: AXL kinase inhibitor (IC50=1.3 nM), also targets MER, MET, TRKA (IC50s: 63, 104, 407 …
Formula:
C41H42FN5O7
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
735.8
Ref: TM-T9123
| 1mg | 106.00 € | ||
| 5mg | 259.00 € | ||
| 10mg | 378.00 € | ||
| 25mg | 702.00 € | ||
| 50mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 283.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Capmatinib 2HCl
CAS:1197376-85-4
Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, …
Formula:
C23H19Cl2FN6O
Purity:
98.80%
Color and Shape:
Solid
Molecular weight:
485.34
Ref: TM-T4260
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 145.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 430.00 € | ||
| 500mg | 998.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SGX-523
CAS:1022150-57-7
SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38α, …
Formula:
C18H13N7S
Purity:
100% - 99.49%
Color and Shape:
Solid
Molecular weight:
359.41
Ref: TM-T2293
| 1mg | 52.00 € | ||
| 2mg | 66.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 279.00 € | ||
| 50mg | 449.00 € | ||
| 100mg | 658.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
(Z)-Semaxinib
CAS:194413-58-6
(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective …
Formula:
C15H14N2O
Purity:
96.09% - ≥95%
Color and Shape:
Solid
Molecular weight:
238.28
Ref: TM-T2496
| 1mg | 57.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 331.00 € | ||
| 50mg | 568.00 € | ||
| 100mg | 695.00 € | ||
| 200mg | 948.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Cabozantinib hydrochloride
CAS:1817759-42-4
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, …
Formula:
C28H25ClFN3O5
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
537.96
Ref: TM-T5164
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 248.00 € | ||
| 100mg | 349.00 € | ||
| 200mg | 568.00 € | ||
| 500mg | 908.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BAY-474
CAS:1033767-86-0
BAY-474 is an inhibitor of tyrosine-protein kinase c-Met. It acts as an epigenetics probe
Formula:
C17H15N5
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
289.33
Ref: TM-T7900
| 1mg | 50.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 306.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 620.00 € | ||
| 200mg | 835.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Afatinib
CAS:850140-72-6
Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and …
Formula:
C24H25ClFN5O3
Purity:
97.56% - 99.9%
Color and Shape:
Off-White Solid
Molecular weight:
485.94
Ref: TM-T21312
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 86.00 € | ||
| 50mg | 115.00 € | ||
| 100mg | 144.00 € | ||
| 200mg | 177.00 € | ||
| 500mg | 300.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AMG-458
CAS:913376-83-7
AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met …
Formula:
C30H29N5O5
Purity:
99.77% - 99.91%
Color and Shape:
Solid
Molecular weight:
539.58
Ref: TM-T6378
| 2mg | 42.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 244.00 € | ||
| 100mg | 338.00 € | ||
| 200mg | 472.00 € |
Estimated delivery in United States, on Tuesday 20 May 2025
SU11274
CAS:658084-23-2
SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects …
Formula:
C28H30ClN5O4S
Purity:
98.62% - 99.44%
Color and Shape:
Orange Powder
Molecular weight:
568.09
Ref: TM-T6154
| 1mg | 47.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 688.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Tuesday 20 May 2025
Glesatinib hydrochloride
CAS:1123838-51-6
Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO.
Formula:
C31H28ClF2N5O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
656.16
Ref: TM-T15383
| 25mg | 907.00 € | ||
| 50mg | 1,179.00 € | ||
| 100mg | 1,890.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Glesatinib
CAS:936694-12-1
Glesatinib is an orally active and potent dual inhibitor of MET/SMO.
Formula:
C31H27F2N5O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
619.7
Ref: TM-T15384
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
