IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
Found 119 products for "IGF-1R".
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Xenin 8 acetate
Xenin 8 acetate is a biologically active fragment of Xenin in the neurotensin/xenopsin family.Formula:C53H83N15O11Purity:99.98%Color and Shape:SolidMolecular weight:1106.32Insulin glulisine
CAS:Insulin glulisine (HMR 1964), a rapid-acting analogue, mimics human insulin; used in diabetes research.Formula:C258H384N64O78S6Color and Shape:SolidMolecular weight:5822.57Insulin peglispro
CAS:Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.Formula:C370H566N104O110S4Color and Shape:SolidMolecular weight:8359.32(Pro3) GIP, human
CAS:(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.Formula:C226H338N60O64SColor and Shape:SolidMolecular weight:4951.53DA-JC4
CAS:DA-JC4: dual GLP-1/GIP agonist, for neurological disease research and insulin pathway studies.Formula:C225H346N56O65Color and Shape:SolidMolecular weight:4875.49Macupatide
CAS:Macupatide is a gastric inhibitory polypeptide (GIP) receptor agonist, utilized in research related to antidiabetic applications.Color and Shape:SolidGIP (1-30) amide, porcine TFA
GIP (1-30) amide, porcine TFA: a full GIP receptor agonist, similar to natural GIP(1-42), stimulates insulin, mildly inhibits gastric acid.Color and Shape:SolidInsulin sensitizer C59
CAS:Insulin sensitizer C59 is an orally available insulin sensitizer that improves glucose uptake and can be used to study insulin-stimulated GLUT4 translocation.Formula:C16H18Cl2N2OPurity:99.84%Color and Shape:White SolidMolecular weight:325.23IGF-1R inhibitor-2
CAS:IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.Formula:C24H24FN7O2Color and Shape:SolidMolecular weight:461.501GIP (1-30) amide,human
CAS:GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.Formula:C162H240N40O47SPurity:98%Color and Shape:SolidMolecular weight:3531.94WAY-270250
CAS:WAY-270250 is an IGF-1R/SRC inhibitor.Formula:C18H16N2O2Purity:99.97%Color and Shape:Green SolidMolecular weight:292.33GIP (1-39)
CAS:Endogenous truncated form of the incretin hormone GIP. More potent at stimulating glucose-dependent insulin secretion from rat pancreatic β-cells than GIP.Formula:C210H316N56O61SPurity:98%Color and Shape:SolidMolecular weight:4633.21CPF-7
CAS:CPF-7 (Caerulein precursor fragment), an insulinotropic peptide, promotes insulin secretion and drives epithelial-mesenchymal transition via Snai1 upregulationFormula:C118H193N33O32Color and Shape:SolidMolecular weight:2586HNMPA-(AM)3
CAS:HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。 此外，HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM，在蚊子和哺乳动物中分别) 具有抑制作用。Formula:C20H23O10PPurity:97.22%Color and Shape:Transparent LiquidMolecular weight:454.36IGF1R/CD221 Protein, Mouse, Recombinant (His)
IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:> 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 90% as determined by HPLCColor and Shape:Lyophilized PowderMolecular weight:80.72+23.0 kDa (predicted); 110-140 kDa and 50-65 kDa, corresponding to the α subunit and β subunit respectively (reducing condition, due to glycosylation)IMP2-IN-1
CAS:IMP2-IN-1 effectively inhibits IMP2 (IC50: 81.3-127.5 μM), reduces IMP2 in SW480 cells, and hinders Huh7 cell activity.Formula:C21H14F3NO4Color and Shape:SolidMolecular weight:401.34IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosisColor and Shape:Lyophilized PowderMolecular weight:105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosisColor and Shape:Lyophilized PowderMolecular weight:105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result.Ersodetug
CAS:Ersodetug is a fully human anti-insulin receptor mAb that treats hypoglycemia in hyperinsulinism by allosterically modulating receptor activity.Purity:95%Picropodophyllin
CAS:Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other growth factor receptors.Formula:C22H22O8Purity:98.38% - 99.83%Color and Shape:White SolidMolecular weight:414.41
